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  1. 11481
    “…Therefore, this study explored the targets and molecular mechanisms of kaempferol against COVID-19/PF co-occurrence by bioinformatics and network pharmacology. Methods: Various open-source databases and Venn Diagram tool were applied to confirm the targets of kaempferol against COVID-19/PF co-occurrence. …”
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    Online Artículo Texto
    Modeling Kaempferol as a Potential Pharmacological Agent for COVID-19/PF Co-Occurrence Based on Bioinformatics and System Pharmacological Tools
  2. 11482
    “…The Malakit information system was developed as a patchwork of existing open-source software, commercial services, and tools developed in-house. …”
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    Online Artículo Texto
    Tailoring Mobile Data Collection for Intervention Research in a Challenging Context: Development and Implementation in the Malakit Study
  3. 11483
    “…CONCLUSION: We developed a series of numerical 4D lung phantoms based on real imaging and motion data, which give realistic representations of both anatomy and motion scenarios and the accessible “ground truth” deformation vector fields of each 4DCT(MRI). The open‐source code and motion data allow foreseen users to generate further 4D data by themselves. …”
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    Online Artículo Texto
    Synthetic 4DCT(MRI) lung phantom generation for 4D radiotherapy and image guidance investigations
  4. 11484
    “…Here, we describe the Brain Imaging Analysis Kit (BrainIAK), an open-source, free Python package that provides computationally optimized solutions to key problems in advanced fMRI analysis. …”
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    BrainIAK: The Brain Imaging Analysis Kit
  5. 11485
    “…Anonymized daily data on the RT-PCR tests conducted in public laboratories belonging to the state-wide network from March 1, 2020 to June 5, 2021 were extracted from the Sao Paulo State open-source database, while the data on the genomic sequences were obtained from GISAID. …”
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    Online Artículo Texto
    Evaluation of the effectiveness of surveillance policies to control the COVID-19 pandemic in São Paulo, Brazil
  6. 11486
    “…OBJECTIVE: To increase the accessibility of Bayesian methods among health surveillance researchers, we introduce a Bayesian methodology and open source software package, surveil, for time-series modeling of disease incidence and mortality. …”
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    Colorectal Cancer Incidence, Inequalities, and Prevention Priorities in Urban Texas: Surveillance Study With the “surveil” Software Package
  7. 11487
    por Acs, Balazs, Leung, Samuel C. Y., Kidwell, Kelley M., Arun, Indu, Augulis, Renaldas, Badve, Sunil S., Bai, Yalai, Bane, Anita L., Bartlett, John M. S., Bayani, Jane, Bigras, Gilbert, Blank, Annika, Buikema, Henk, Chang, Martin C., Dietz, Robin L., Dodson, Andrew, Fineberg, Susan, Focke, Cornelia M., Gao, Dongxia, Gown, Allen M., Gutierrez, Carolina, Hartman, Johan, Kos, Zuzana, Lænkholm, Anne-Vibeke, Laurinavicius, Arvydas, Levenson, Richard M., Mahboubi-Ardakani, Rustin, Mastropasqua, Mauro G., Nofech-Mozes, Sharon, Osborne, C. Kent, Penault-Llorca, Frédérique M., Piper, Tammy, Quintayo, Mary Anne, Rau, Tilman T., Reinhard, Stefan, Robertson, Stephanie, Salgado, Roberto, Sugie, Tomoharu, van der Vegt, Bert, Viale, Giuseppe, Zabaglo, Lila A., Hayes, Daniel F., Dowsett, Mitch, Nielsen, Torsten O., Rimm, David L.
    Publicado 2022
    “…Ki67 has potential clinical importance in breast cancer but has yet to see broad acceptance due to inter-laboratory variability. Here we tested an open source and calibrated automated digital image analysis (DIA) platform to: (i) investigate the comparability of Ki67 measurement across corresponding core biopsy and resection specimen cases, and (ii) assess section to section differences in Ki67 scoring. …”
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    Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study
  8. 11488
    “…METHODS: We conducted a study using Bengali text-based data from blogs and open source platforms. We constructed a procedure for annotated corpus generation and extraction of textual information from Bengali literature for predictive analysis. …”
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    Detection of Depression Severity Using Bengali Social Media Posts on Mental Health: Study Using Natural Language Processing Techniques
  9. 11489
    “…METHODS: Data collection was undertaken based on geospatial open-source technologies and the collaborative mapping platform OpenStreetMap using a systematic approach involving three phases: remote mapping, ground-truthing, and food-outlet survey. …”
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    Type, density, and healthiness of food-outlets in a university foodscape: a geographical mapping and characterisation of food resources in a Ghanaian university campus
  10. 11490
    “…Cases of COVID-19 mirrored national trends derived from open source data, while the dearth of influenza cases mirrored national and global Flunet figures. …”
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    Dearth of influenza among older adults admitted with respiratory symptoms in Malaysia during the coronavirus disease 2019 pandemic in 2021
  11. 11491
    “…CONCLUSIONS: We successfully developed high-performance algorithms that identified whether a citation was a CRT report with high sensitivity and moderately high specificity. We provide open-source software to facilitate the use of our algorithms in practice. …”
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    Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE
  12. 11492
    “…Molecular docking was done by AutoDock Vina 4.2 open-source program. DFT calculations were performed using the Gaussian 16 program package. …”
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    Antibacterial and Antioxidant Activities, in silico Molecular Docking, ADMET and DFT Analysis of Compounds from Roots of Cyphostemma cyphopetalum
  13. 11493
    “…In 2015, Apple launched an open-source software framework called ResearchKit. ResearchKit provides an infrastructure for conducting remote, smartphone-based research trials through the means of Apple's App Store. …”
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    The feasibility of using Apple's ResearchKit for recruitment and data collection: Considerations for mental health research
  14. 11494
    “…Active compounds and potential targets of CP, as well as the potential targets related to HUA, were retrieved from multiple open-source databases. The drug-disease overlapping targets were obtained by Venn diagram analysis and used to construct the herb-component-target (HCT), protein-protein-interaction (PPI), and component-target-pathway (CTP) networks. …”
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    Integrating network pharmacology and experimental validation to clarify the anti-hyperuricemia mechanism of cortex phellodendri in mice
  15. 11495
    “…The intervention design is based on the transtheoretical model and is implemented in a mobile app using the MobileCoach open-source platform. The effectiveness of the intervention will be elucidated by a 9-week, 2-armed, parallel-designed trial. …”
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    Mobile Digital Health Intervention to Promote Nutrition and Physical Activity Behaviors Among Long-term Unemployed in Rural Areas: Protocol for a Randomized Controlled Trial
  16. 11496
    “…CONCLUSIONS: T3E is a novel open-source computational tool (available for use at: https://github.com/michelleapaz/T3E) that overcomes some of the pitfalls associated with the analysis of ChIP-seq data arising from the repetitive mammalian genome and provides a framework to shed light on the epigenetics of entire TE families/subfamilies. …”
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    T3E: a tool for characterising the epigenetic profile of transposable elements using ChIP-seq data
  17. 11497
    “…RESULTS: To overcome these barriers, we have developed the tool EasySMPC, which is implemented in Java as a cross-platform, stand-alone desktop application provided as open-source software. The tool makes use of the SMPC method Arithmetic Secret Sharing, which allows to securely sum up pre-defined sets of variables among different parties in two rounds of communication (input sharing and output reconstruction) and integrates this method into a graphical user interface. …”
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    Online Artículo Texto
    EasySMPC: a simple but powerful no-code tool for practical secure multiparty computation
  18. 11498
    “…This model, widely used in North America, is not open source and therefore cannot be applied to patient populations in other settings. …”
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    Development and internal validation of a model for postoperative morbidity in adults undergoing major elective colorectal surgery: the peri‐operative quality improvement programme (PQIP) colorectal risk model
  19. 11499
    “…METHODS: For longitudinal studies of health outcomes from environmental exposures, we show how to [1] conduct a power analysis that aligns with the planned mixed model data analysis, [2] gather the inputs required for the power analysis, and [3] conduct repeated measures power analysis with a highly-cited, validated, free, point-and-click, web-based, open source software platform which was developed specifically for scientists. …”
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    Power and sample size analysis for longitudinal mixed models of health in populations exposed to environmental contaminants: a tutorial
  20. 11500
    “…IMPORTANCE: Lung cancer screening with chest computed tomography (CT) prevents lung cancer death; however, fewer than 5% of eligible Americans are screened. CXR-LC, an open-source deep learning tool that estimates lung cancer risk from existing chest radiograph images and commonly available electronic medical record (EMR) data, may enable automated identification of high-risk patients as a step toward improving lung cancer screening participation. …”
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    Validation of a Deep Learning–Based Model to Predict Lung Cancer Risk Using Chest Radiographs and Electronic Medical Record Data
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