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2061
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2062por Sanfins, Milaine Dominici, Gielow, Ingrid, Madazio, Glaucya, Honorio, Francine, Bordin, Tatiana, Skarzynski, Piotr Henryk, Skarzynska, Magdalena Beata, Behlau, Mara“…These sounds can originate in different ways, such as a musical instrument, orchestra, or the human voice. Objective The objective of the present work is to study frequency-following responses (FFRs) in individuals who can sing in-tune and those who sing off-tune. …”
Publicado 2023
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2063“…Within the TME, epithelial cancer cells control the function of surrounding stromal cells and the non-cellular ECM components in an intricate orchestra of signaling networks specifically designed for cancer cells to exploit surrounding cells for their own benefit. …”
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2064por Rozwadowska, Natalia, Kolanowski, Tomasz, Wiland, Ewa, Siatkowski, Marcin, Pawlak, Piotr, Malcher, Agnieszka, Mietkiewski, Tomasz, Olszewska, Marta, Kurpisz, Maciej“…Cell differentiation is based on a synchronised orchestra of complex pathways of intrinsic and extrinsic signals that manifest in the induced expression of specific transcription factors and pivotal genes within the nucleus. …”
Publicado 2013
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2065“…The ORCHESTRA online questionnaire on “benefits and barriers to the use of QSAR methods” addressed the academic, consultant, regulatory and industry communities potentially interested by QSAR methods in the context of REACH. …”
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2066por Sziksz, Erna, Pap, Domonkos, Lippai, Rita, Béres, Nóra Judit, Fekete, Andrea, Szabó, Attila J., Vannay, Ádám“…Infiltrating immune cells, endothelial, epithelial, and other resident cells of the injured organ release an orchestra of inflammatory mediators, which stimulate the proliferation and excessive extracellular matrix (ECM) production of myofibroblasts, the effector cells of organ fibrosis. …”
Publicado 2015
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2067“…The acoustic analysis revealed that the dynamic range of samples from popular genres, such as rock or rap, was generally smaller than the dynamic range of samples from classical genres, such as opera and orchestra. By comparison, the dynamic range of speech, based on recordings of monologues in quiet, was larger than the dynamic range of all music genres tested. …”
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2068por Alsereihi, Reem, Schulten, Hans-Juergen, Bakhashab, Sherin, Saini, Kulvinder, Al-Hejin, Ahmed M., Hussein, Deema“…Based on experiments in various biological models, this review shows an orchestra of multiple molecules that regulate AGR2 expression, including a feedback loop with p53. …”
Publicado 2019
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2069por Calabrò, Rocco S., Cacciola, Alberto, Bruschetta, Daniele, Milardi, Demetrio, Quattrini, Fabrizio, Sciarrone, Francesca, la Rosa, Gianluca, Bramanti, Placido, Anastasi, Giuseppe“…RESULTS: Sexual behavior is regulated by both subcortical structures, such as the hypothalamus, brainstem, and spinal cord, and several cortical brain areas acting as an orchestra to finely adjust this primitive, complex, and versatile behavior. …”
Publicado 2019
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2070“…Metagenome-Assembled Genomes Orchestra (MAGO) is a computational framework that integrates and simplifies metagenome assembly, binning, bin improvement, bin quality (completeness and contamination), bin annotation, and evolutionary placement of bins via detailed maximum-likelihood phylogeny based on multiple marker genes using different amino acid substitution models, next to average nucleotide identity analysis of genomes for delineation of species boundaries and operational taxonomic units. …”
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2071“…Moreover, lncRNAs regulate orchestra of diverse functions including chromatin organization and transcriptional and post-transcriptional regulation. …”
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2072por Moing, Annick, Allwood, J. William, Aharoni, Asaph, Baker, John, Beale, Michael H., Ben-Dor, Shifra, Biais, Benoît, Brigante, Federico, Burger, Yosef, Deborde, Catherine, Erban, Alexander, Faigenboim, Adi, Gur, Amit, Goodacre, Royston, Hansen, Thomas H., Jacob, Daniel, Katzir, Nurit, Kopka, Joachim, Lewinsohn, Efraim, Maucourt, Mickael, Meir, Sagit, Miller, Sonia, Mumm, Roland, Oren, Elad, Paris, Harry S., Rogachev, Ilana, Rolin, Dominique, Saar, Uzi, Schjoerring, Jan K., Tadmor, Yaakov, Tzuri, Galil, de Vos, Ric C.H., Ward, Jane L., Yeselson, Elena, Hall, Robert D., Schaffer, Arthur A.“…Metabolomics data of the mature fruit flesh and rind provided over 80,000 metabolomic and elemental features via an orchestra of six complementary metabolomic platforms. …”
Publicado 2020
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2073por Vita, Gian Marco, De Simone, Giovanna, Leboffe, Loris, Montagnani, Francesca, Mariotti, Davide, Di Bella, Stefano, Luzzati, Roberto, Gori, Andrea, Ascenzi, Paolo, di Masi, Alessandra“…Recent evidence suggests that human serum albumin (HSA), the most abundant protein in plasma, is a player in the innate immunity “orchestra.” We previously demonstrated that HSA acts as a physiological buffer, partially neutralizing Clostridioides difficile toxins that reach the bloodstream after being produced in the colon. …”
Publicado 2020
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2074por Semyachkina-Glushkovskaya, O., Esmat, A., Bragin, D., Bragina, O., Shirokov, A. A., Navolokin, N., Yang, Y., Abdurashitov, A., Khorovodov, A., Terskov, A., Klimova, M., Mamedova, A., Fedosov, I., Tuchin, V., Kurths, J.“…However, the unsafe listening of loud music triggers hearing loss in millions of young people and professional musicians (rock, jazz and symphony orchestra) owing to exposure to damaging sound levels using personal audio devices or at noisy entertainment venues including nightclubs, discotheques, bars and concerts. …”
Publicado 2020
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2075por Khalid, Subaina Naeem, Khan, Zeest Ali, Ali, Muhammad Hamza, Almas, Talal, Khedro, Tarek, Raj Nagarajan, Vikneswaran“…In recent times, more complex elements of the underlying inflammatory orchestra have been elucidated and are being used to develop targeted immunotherapies. …”
Publicado 2021
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2076por Musumeci, Teresa, Di Benedetto, Giulia, Carbone, Claudia, Bonaccorso, Angela, Amato, Giovanni, Lo Faro, Maria Josè, Burgaletto, Chiara, Puglisi, Giovanni, Bernardini, Renato, Cantarella, Giuseppina“…Tumor necrosis factor (TNF)-Related Apoptosis Inducing Ligand (TRAIL), a proinflammatory cytokine belonging to the TNF superfamily, appears to be a key player in the inflammatory/immune orchestra of the AD brain. Despite the ability of an anti-TRAIL monoclonal antibody to reach the brain producing beneficial effects in AD mice, we attempted to develop such a TRAIL-neutralizing monoclonal antibody adsorbed on lipid and polymeric nanocarriers, for intranasal administration, in a valid approach to overcome issues related to both high dose and drug transport across the blood–brain barrier. …”
Publicado 2022
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2077“…Several small molecules generate daily circadian fluctuations ensuring inter-organ communication and coordination between external stimuli, i.e., light, food, and exercise, and body metabolism. As an orchestra, this complex network can be out of tone. …”
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2078por Kurbatov, Ilya, Dolgalev, Georgii, Arzumanian, Viktoriia, Kiseleva, Olga, Poverennaya, Ekaterina“…Increasing attention has been focused on the study of protein–metabolite interactions (PMI), which play a key role in regulating protein functions and directing an orchestra of cellular processes. The investigation of PMIs is complicated by the fact that many such interactions are extremely short-lived, which requires very high resolution in order to detect them. …”
Publicado 2023
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2079
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2080