“…Moreover, recent studies have uncovered a crucial role for bacterial post-biotics (metabolites) in the orchestration of the host immune response, as they could be messengers between the GM and the immune system. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…From protein interactions to signal transduction, from metabolism to the nervous system: Virtually all processes in health and disease rely on the careful orchestration of a large number of diverse individual components ranging from molecules to cells and entire organs. …”
Enlace del recurso
Enlace del recurso

“…Organs and tissues, such as cartilage and limbs, are formed during development through an orchestration of growth factors that function as morphogens. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The first is the traditional one: the ‘global orchestration’ of resources and markets. We argue that it exacerbates local disconnectedness. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Bioinformatic analysis of the data revealed a coherent orchestration of biological processes underlying T‐cell activation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we set out to elucidate the spatiotemporal orchestration of late adenovirus nuclear remodeling in living cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recently, the role of mitochondrial activity in high-energy demand organs and in the orchestration of whole-body metabolism has received renewed attention. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the telencephalic neuroepithelium, this is controlled in part by cell adhesion molecules and regulators of progenitor cell lineage, but the specific orchestration of these processes remains unknown. Here, we studied the role of microRNAs in the embryonic telencephalon as key regulators of gene expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The impact of helminths on the pulmonary immune response involves a sophisticated orchestration and activation of the host innate and adaptive immune cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We propose a novel model of how individual pDCs are endowed to exert different functions in vivo during a viral infection in a manner tightly orchestrated in time and space.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Both pharmacological approaches and diets with a low carbohydrate content are under evaluation in order to limit glucose availability in metabolic processes for a future application as co-adjuvant strategies to improve cancer immunotherapies. ABSTRACT: The orchestration of T cell responses is intimately linked to the execution of metabolic processes, both in homeostasis and disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In particular, we focus on, how potential is the fog computing orchestration framework? How it can be customized to the next generation of cellular communication systems? …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Innate lymphoid cells (ILCs) represent the most recently identified subset of effector lymphocytes, with key roles in the orchestration of early immune responses. Despite their established involvement in the pathogenesis of many inflammatory disorders, the role of ILCs in cancer remains poorly defined. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The workflow is written by using Nextflow, a workflow orchestration software, to achieve high reproducibility and fast and straightforward use. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Exciting new reagents which induce TLS in preclinical cancer models provide mechanistic insights into the exquisite stromal orchestration of TLS formation, a process often associated with a more functional or “normalized” tumor vasculature and fueled by LIGHT/LTα/LTβ, TNFα and CC/CXC chemokine signaling. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cyclins and CDKs (Cyclin Dependent Kinases) are key players in the biology of eukaryotic cells, representing hubs for the orchestration of physiological conditions with cell cycle progression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…IL-6 was first recognized as a B-cell stimulating factor but we now know that the cytokine plays a pivotal role in the orchestration of inflammatory processes as well as in inflammation associated cancer. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This review will cover lactate secretion and sensing in humans and microbes, and will discuss the existing evidence supporting a role for lactate in pathogen growth and persistence, together with lactate's ability to impact the orchestration of effective immune responses. The ubiquitous presence of lactate in the context of infection and the ability of both host cells and pathogens to sense and respond to it, makes manipulation of lactate a potential novel therapeutic strategy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this paper, we present FISHY as a preliminary architecture that is designed to orchestrate existing and beyond state-of-the-art security appliances in composed ICT scenarios. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…But the pivotal challenge for 5G & B5G connectivity solutions is to ensure flexible and agile service orchestration with acknowledged Quality of Experience (QoE). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso