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2081por Fathima, Afifa Salsabil, Basha, Syed Muzamil, Ahmed, Syed Thouheed, Mathivanan, Sandeep Kumar, Rajendran, Sukumar, Mallik, Saurav, Zhao, Zhongming“…Central to this endeavor are multi-objective optimal datasets (MooM), characterized by attribute-driven feature cartography and cluster categorization through the conduit of federated learning models. The orchestration of feature synchronization and parameter extraction transpires across multiple tiers of neural networking, culminating in the provisioning of a steadfast remedy through dataset standardization and labeling. …”
Publicado 2023
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2082por Sainz, Ricardo M., Rodriguez-Quintero, Jorge Humberto, Maldifassi, Maria Constanza, Stiles, Brendon M., Wennerberg, Erik“…While P2X7 receptor expression on tumour cells has been characterized as a promotor of cancer growth and metastasis, its expression by the host immune system is central for orchestration of both innate and adaptive immune responses against cancer. …”
Publicado 2023
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2083por Ng, Lai Guan, Hsu, Alice, Mandell, Michael A., Roediger, Ben, Hoeller, Christoph, Mrass, Paulus, Iparraguirre, Amaya, Cavanagh, Lois L., Triccas, James A., Beverley, Stephen M., Scott, Phillip, Weninger, Wolfgang“…The spatio-temporal orchestration of antigen encounter by dermal DC (DDC) is not known. …”
Publicado 2008
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2084por Bernstein, N. K., Hammel, M., Mani, R. S., Weinfeld, M., Pelikan, M., Tainer, J. A., Glover, J. N. M.“…The flexible attachment of the FHA domain to the catalytic segment, elucidated by SAXS, enables the interactions of mPNK with diverse DNA substrates and protein partners required for effective orchestration of DNA end repair. Point mutations surrounding the kinase active site identified two substrate recognition surfaces positioned to contact distinct regions on either side of the phosphorylated 5′-hydroxyl. …”
Publicado 2009
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2085por Fuchikami, Manabu, Yamamoto, Shigeto, Morinobu, Shigeru, Takei, Shiro, Yamawaki, Shigeto“…It is suggested that these plastic changes are due to orchestration of alterations in gene expression in the brain. …”
Publicado 2010
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2086“…We propose that Mad2 is an important meiotic cell cycle regulator that ensures the timely degradation of APC/C substrates and the proper orchestration of the meiotic divisions.…”
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2087por da Silva, Maria Fernanda Laranjeira, Zampieri, Ricardo Andrade, Muxel, Sandra M., Beverley, Stephen M., Floeter-Winter, Lucile M.“…Our conjecture is that parasite arginase participates in a complex equilibrium that defines the fate of L-arginine and that its proper subcellular location may be essential for this physiological orchestration.…”
Publicado 2012
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2088“…CONCLUSION: These findings suggest that while the orchestration of multiple scales of visual content is required for normal eye-guidance during reading, a broad range of visual content can activate processes of word identification independently. …”
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2089“…In plants, the intercellular communication through the membranous channels called plasmodesmata (PD; singular plasmodesma) plays pivotal roles in the orchestration of development, defence responses, and viral propagation. …”
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2090“…Chemokines play a key role in the orchestration of immune responses, acting both as chemoattractants and activators of leukocyte subsets. …”
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2091“…Together, our results reveal that EBs are obligatory dimers, a conclusion that has implications for the mechanistic understanding of these key proteins involved in the orchestration of dynamic protein networks at growing microtubule ends.…”
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2092por Vidi, Pierre-Alexandre, Liu, Jing, Salles, Daniela, Jayaraman, Swaathi, Dorfman, George, Gray, Matthew, Abad, Patricia, Moghe, Prabhas V., Irudayaraj, Joseph M., Wiesmüller, Lisa, Lelièvre, Sophie A.“…These findings reveal a structural basis for the orchestration of chromatin remodeling whereby a scaffold protein promotes genome maintenance by directing a remodeler to DNA breaks.…”
Publicado 2014
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2093“…Finding optimal rehabilitation paradigms requires an optimal orchestration of the internal processes of re-organization and the therapeutic interventions in accordance with defined plastic time windows. …”
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2094por Uddin, Mohammad Nazim, Dunoyer, Patrice, Schott, Gregory, Akhter, Salina, Shi, Chunlin, Lucas, William J., Voinnet, Olivier, Kim, Jae-Yean“…Gene regulations by RNA silencing have fundamental implications in a large number of biological processes that include antiviral defense, maintenance of genome integrity and the orchestration of cell fates. Although most generic or core components of the various plant small RNA pathways have been likely identified over the past 15 years, factors involved in RNAi regulation through post-translational modifications are just starting to emerge, mostly through forward genetic studies. …”
Publicado 2014
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2095“…We tentatively hypothesize that the resolution of recalibration in complex scenarios involves the orchestration of top-down selection mechanisms and stimulus-driven processes.…”
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2096por Matsoukas, Ianis G.“…This includes interactions with phytohormones that are also important for the orchestration of developmental phase transitions, including gibberellins, abscisic acid, ethylene, and brassinosteroids. …”
Publicado 2014
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2097“…Optimal metabolic health is thus the orchestration of all mechanisms and processes that maintain this flexibility in an organism as a phenotype. …”
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2098por Sanulli, Serena, Justin, Neil, Teissandier, Aurélie, Ancelin, Katia, Portoso, Manuela, Caron, Matthieu, Michaud, Audrey, Lombard, Berangère, da Rocha, Simao T., Offer, John, Loew, Damarys, Servant, Nicolas, Wassef, Michel, Burlina, Fabienne, Gamblin, Steve J., Heard, Edith, Margueron, Raphaël“…Deletion of Jarid2 leads to impaired orchestration of gene expression during cell lineage commitment. …”
Publicado 2015
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2099“…Plant mitochondria constitute a major source of ROS and are proposed to act as signaling organelles in the orchestration of defense response. At present, the signals generated and then integrated by mitochondria are still limited. …”
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2100por Hadjipanayi, Ektoras, Kuhn, Peer-Hendrik, Moog, Philipp, Bauer, Anna-Theresa, Kuekrek, Haydar, Mirzoyan, Lilit, Hummel, Anja, Kirchhoff, Katharina, Salgin, Burak, Isenburg, Sarah, Dornseifer, Ulf, Ninkovic, Milomir, Machens, Hans-Günther, Schilling, Arndt F.“…The mechanisms facilitating orchestration of these events remain poorly understood, however, likely due to limitations in discerning the individual contribution of cells and extracellular matrix. …”
Publicado 2015
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