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  1. 2561
    “…CONCLUSION: These results confirm profound in situ EBV deregulation and suggest orchestration of local antiviral function in the MS brain, lending support to a model of MS pathogenesis that involves EBV as possible antigenic stimulus of the persistent immune response in the central nervous system. …”
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    Transcriptional profile and Epstein-Barr virus infection status of laser-cut immune infiltrates from the brain of patients with progressive multiple sclerosis
  2. 2562
    por Peters, Kristian, Bradbury, James, Bergmann, Sven, Capuccini, Marco, Cascante, Marta, de Atauri, Pedro, Ebbels, Timothy M D, Foguet, Carles, Glen, Robert, Gonzalez-Beltran, Alejandra, Günther, Ulrich L, Handakas, Evangelos, Hankemeier, Thomas, Haug, Kenneth, Herman, Stephanie, Holub, Petr, Izzo, Massimiliano, Jacob, Daniel, Johnson, David, Jourdan, Fabien, Kale, Namrata, Karaman, Ibrahim, Khalili, Bita, Emami Khonsari, Payam, Kultima, Kim, Lampa, Samuel, Larsson, Anders, Ludwig, Christian, Moreno, Pablo, Neumann, Steffen, Novella, Jon Ander, O'Donovan, Claire, Pearce, Jake T M, Peluso, Alina, Piras, Marco Enrico, Pireddu, Luca, Reed, Michelle A C, Rocca-Serra, Philippe, Roger, Pierrick, Rosato, Antonio, Rueedi, Rico, Ruttkies, Christoph, Sadawi, Noureddin, Salek, Reza M, Sansone, Susanna-Assunta, Selivanov, Vitaly, Spjuth, Ola, Schober, Daniel, Thévenot, Etienne A, Tomasoni, Mattia, van Rijswijk, Merlijn, van Vliet, Michael, Viant, Mark R, Weber, Ralf J M, Zanetti, Gianluigi, Steinbeck, Christoph
    Publicado 2018
    “…PhenoMeNal seamlessly integrates a wide array of existing open-source tools that are tested and packaged as Docker containers through the project's continuous integration process and deployed based on a kubernetes orchestration framework. It also provides a number of standardized, automated, and published analysis workflows in the user interfaces Galaxy, Jupyter, Luigi, and Pachyderm. …”
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    PhenoMeNal: processing and analysis of metabolomics data in the cloud
  3. 2563
    “…Due to irregular oncogenes orchestration, tumor cells exhibit distinct fatty acid metabolic features from non-tumor cells. …”
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    MYCN and PRC1 cooperatively repress docosahexaenoic acid synthesis in neuroblastoma via ELOVL2
  4. 2564
    “…The proposed digital health platform was designed to support hypertension care coordination and continuity through clinical workflow orchestration, decision support, and patient-mediated data sharing with privacy preservation, auditability, and trust enabled by blockchain technology. …”
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    Addressing Care Continuity and Quality Challenges in the Management of Hypertension: Case Study of the Private Health Care Sector in Kenya
  5. 2565
    “…From a total of about forty mitosomes, a small, privileged population is harnessed to the flagellar apparatus, and their life cycle is coordinated with the maturation cycle of G. intestinalis flagella. The orchestration of mitosomal inheritance with the flagellar maturation cycle is mediated by a microtubular connecting fiber, which physically links the privileged mitosomes to both axonemes of the oldest flagella pair and guarantees faithful segregation of the mitosomes into the daughter cells. …”
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    Inheritance of the reduced mitochondria of Giardia intestinalis is coupled to the flagellar maturation cycle
  6. 2566
    “…WO reaction, that is, the production of molecular oxygen and protons from water, requires the formation of an O–O bond through the orchestration of multiple proton and electron transfers. …”
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    The Impact of Ligand Carboxylates on Electrocatalyzed Water Oxidation
  7. 2567
    por Fredericks, Robert S
    Publicado 2022
    “…This Warburg effect, recognized in proliferating malignant cells, was observed at the systemic level in humans and, modeled as mediated by hypoxia inducible factors regulating glucose uptake and suppression of beta-oxidation. Higher order orchestration is governed by a signaling structure including PTH, PTHrP, FGF23, Klotho, prolactin, growth hormone, IGFs, insulin, SGLT2, thyroid, adrenal and vit D while salt inducible kinase contributes to understanding of terrestrial adaptation. …”
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    LBSUN152 The Warburg Effect And Complex Thermomics Inform Phenotypic Expression
  8. 2568
    “…In this study, the authors present MOdality Mapping and Orchestration (MOMO), a Deep Learning–based approach to automate this mapping process by combining metadata analysis and a neural network ensemble. …”
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    Deep Learning–driven classification of external DICOM studies for PACS archiving
  9. 2569
    por Liszt, Franz, 1811-1886
    Publicado 1998
    Tabla de Contenidos: “…Concerto no. 2 in A major, S125 (21:04) ; De profundis : psaume instrumental pour orchestre et piano principal, S691 (36:13) ; Grosse Fantasie "Wanderer" / Schubert ; arranged for piano and orchestra by Liszt, S366 (21:55) -- Disc 2. …”
    CD Audiom
    Music for piano and orchestra.
  10. 2570
    Publicado 1995
    Tabla de Contenidos: “…Divertissement / Ibert -- Danse macabre, op. 40 ; Le rouet d'Omphale, op. 31 / Saint-Saëns -- Jeux d'enfants: petite suite d'orchestre, op. 22 / Bizet -- Overture: Le carnaval romain ; Hungarian March from La damnation de Faust ; Overture: Le corsaire / Berlioz.…”
    CD Audiom
    Ibert, Saint-Sains, Bizet, Berlioz
  11. 2571
    por Wagner, Siegfried, 1869-1930
    Publicado 1996
    Tabla de Contenidos: “…Concerto for violin with orchestral accompaniment (24:28) -- Der Kobold : op. 3. …”
    CD Audiom
    Violin concerto Flute concertino ; Das Märchen /
  12. 2572
    “…While however, little is known about the orchestration of all BVDV in the context of viral virulence and immunogenicity. …”
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    Immunoinformatic prediction of the pathogenicity of bovine viral diarrhea virus genotypes: implications for viral virulence determinants, designing novel diagnostic assays and vaccines development
  13. 2573
    “…RESULTS: Development of fruit from flower involves orchestration of myriad molecular switches. We did comparative transcriptome sequencing on leaf, flower and fruit tissues of cv. …”
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    RNA-sequencing based gene expression landscape of guava cv. Allahabad Safeda and comparative analysis to colored cultivars
  14. 2574
    “…CONCLUSION: This Drosophila embryonic atlas broadly informs the orchestration of cellular states during the most dynamic stages in the life cycle of metazoan organisms. …”
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    The continuum of Drosophila embryonic development at single-cell resolution
  15. 2575
    “…Colorectal cancer is the third most diagnosed cancer and the second leading cause of cancer mortality worldwide, highlighting an urgent need for new therapeutic options and combination strategies for patients. The orchestration of potent T cell responses against human cancers is necessary for effective antitumour immunity. …”
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    Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer
  16. 2576
    “…RESULTS: Nine randomized controlled trials were obtained comprising six treatment regimens, including 1912 patients with pathogenic variants of BRCA1 and BRCA2. The orchestration of PARP inhibitors with platinum-based chemotherapy was found to be the most effective with a pooled odds ratio (OR) of 3.52 (95% CI 2.14, 5.78) for ORR; 1.53 (1.34,1.76), 3.05 (1.79, 5.19), and 5.80 (1.42, 23.77) for 3-, 12-, and 24-month PFS, respectively, and 1.04 (1.00, 1.07), 1.76 (1.25, 2.49) and 2.31 (1.41, 3.77) for 3-, 12-, and 36-month OS, respectively compared to those receiving non-platinum-based chemotherapy. …”
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    Efficacy and safety of treatment regimens for patients with metastatic, locally advanced, or recurrent breast cancer carrying BRCA1/BRCA2 pathogenic variants: A network meta-analysis
  17. 2577
    por Lekeu, Guillaume, 1870-1894
    Publicado 1990
    Tabla de Contenidos: “…Chant de triumphale délivrance (9:22) -- Seconde étude symphonique. 1re partie : Hamlet (13:24) ; 2re partie : Ophélie (6:56) -- Fantaisie sur deux Airs populaires angevins (13:00) -- Adagio pour quatuor d'orchestre (12:28).…”
    CD Audiom
    Oeuvres symphoniques
  18. 2578
    por Buchmann, Kurt
    Publicado 2014
    “…Cytokines take part in this orchestration of responses even in lower invertebrates, which eventually may result in elimination or inactivation of the intruder. …”
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    Evolution of Innate Immunity: Clues from Invertebrates via Fish to Mammals
  19. 2579
    “…CONCLUSIONS: Our observations provide evidence that the orchestration of the MSC-secreted Wnts could promote the survival and improve the endothelial function of the injured islet endothelium via activating the β-catenin-dependent Wnt signaling in target endothelial cells. …”
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    Mesenchymal stromal cells ameliorate oxidative stress-induced islet endothelium apoptosis and functional impairment via Wnt4-β-catenin signaling
  20. 2580
    “…The secretomes were digested and analyzed by nanoLC-MS/MS to unravel the orchestration of proteins. RESULTS: The inflammatory proteins IL6, CXCL1, CXCL6, CCL7, SEMA7A, SAA, and haptoglobin were identified in the secretome after 48 h from all cells stimulated with IL-1β. …”
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    Mass spectrometric analysis of the in vitro secretome from equine bone marrow-derived mesenchymal stromal cells to assess the effect of chondrogenic differentiation on response to interleukin-1β treatment
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