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2864“…Taspase 1 (TASP1) cleaves the mixed-lineage leukemia (MLL) and transcription factor (TF) IIA families of nuclear proteins to orchestrate various biological processes. TASP1 is not a classical oncogene, but assists in cell proliferation and permits oncogenic initiation through cleavage of MLL and TFIIA. …”
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2865“…Abnormally excessive growth results from perturbation of a complex interplay of genetic, epigenetic, and hormonal factors that orchestrate human growth. Overgrowth syndromes generally present with inherent health concerns and, in some instances, an increased risk of tumor predisposition that necessitate prompt diagnosis and appropriate referral. …”
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2866por Ding, Hongxu, Yang, Ying, Xue, Yuanqing, Seninge, Lucas, Gong, Henry, Safavi, Rojin, Califano, Andrea, Stuart, Joshua M.“…Biological states are controlled by orchestrated transcriptional factors (TFs) within gene regulatory networks. …”
Publicado 2020
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2867por Taylor, Seth R, Kobayashi, Mariko, Vilella, Antonietta, Tiwari, Durgesh, Zolboot, Norjin, Du, Jessica X, Spencer, Kathryn R, Hartzell, Andrea, Girgiss, Carol, Abaci, Yusuf T, Shao, Yufeng, De Sanctis, Claudia, Bellenchi, Gian Carlo, Darnell, Robert B, Gross, Christina, Zoli, Michele, Berg, Darwin K, Lippi, Giordano“…The assembly of the mammalian brain is orchestrated by temporally coordinated waves of gene expression. …”
Publicado 2023
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2868“…Here, we tested the hypothesis that caspase-2 (CASP2) orchestrates apoptosis of axotomised DRGN both in vivo and in vitro by disrupting the local neurotrophic supply to DRGN. …”
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2869por Farahani, Rahim, Sherkat, Roya, Hakemi, Mazdak Ganjalikhani, Eskandari, Nahid, Yazdani, Reza“…It was believed that airway inflammation is orchestrated by allergen specific T helper (Th) 2 cells, which recruit and accumulate in the lungs and produce a range of different effector cytokines. …”
Publicado 2014
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2870por Li, Hai-yan, Guo, Qi, Song, Wei-dong, Zhou, Yi-ping, Li, Ming, Chen, Xiao-ke, Liu, Hui, Peng, Hong-lin, Yu, Hai-qiong, Chen, Xia, Liu, Nian, Lü, Zhong-dong, Liang, Li-hua, Zhao, Qing-zhou, Jiang, Mei“…The IDSA/ATS minor criteria could be simplified to 5 variables and then be modified to orchestrate improvements in predicting mortality in CAP patients. …”
Publicado 2015
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2871“…Drugs that disrupt the components of this highly orchestrated multi-organ process can lead to life-threatening hyperthermia. …”
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2872por Grandl, Gerald, Müller, Sebastian, Moest, Hansjörg, Moser, Caroline, Wollscheid, Bernd, Wolfrum, Christian“…Different adipose depots respond differently to an increased demand for lipid storage. Orchestrating cellular expansion in vivo requires extracellular matrix (ECM) remodeling and a high degree of interaction between cells and ECM. …”
Publicado 2016
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2873“…Scaffold proteins such as the multidomain protein CNK1 orchestrate the signalling network by integrating and controlling the underlying pathways. …”
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2874“…The final ripe fruit is the result of a process under multiple levels of regulation, including mechanisms orchestrated by microRNAs and lncRNAs. Most of the studies we discuss involve work on tomato and Arabidopsis. …”
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2875por Spracklen, Andrew J., Thornton-Kolbe, Emma M., Bonner, Alison N., Florea, Alexandru, Compton, Peter J., Fernandez-Gonzalez, Rodrigo, Peifer, Mark“…Thus, Crk regulates diverse events in embryogenesis that require orchestrated cytoskeletal dynamics.…”
Publicado 2019
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2876por Saurav, Kumar, Borbone, Nicola, Burgsdorf, Ilia, Teta, Roberta, Caso, Alessia, Bar-Shalom, Rinat, Esposito, Germana, Britstein, Maya, Steindler, Laura, Costantino, Valeria“…The obtained results show the coexistence of QS and QSI in S. spinosulus, a complex signal network that may mediate the orchestrated function of the microbiome within the sponge holobiont.…”
Publicado 2020
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2877“…Interestingly, calcium signaling, HCN channel expression and ACh signaling, crucial for orchestrating the alpha rhythm, are also known to be aberrational in AD. …”
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2878por Zhuang, Tongtian, Yi, Xiuli, Chen, Jianru, Kang, Pan, Chen, Xuguang, Chen, Jiaxi, Cui, Tingting, Chang, Yuqian, Ye, Zhubiao, Ni, Qingrong, Wang, Yinghan, Du, Pengran, Li, Baizhang, Liu, Ling, Jian, Zhe, Li, Kai, Gao, Tianwen, Li, Shuli, Li, Chunying“…More importantly, IFN-β mediated by the MDA5-MAVS-NF-κB/IRF3 signaling pathway orchestrated the secretion of CXCL10 via the JAK1-STAT1 pathway and MDA5-meidiated IRF3 transcriptionally induced the production of CXCL16 in keratinocytes under virus invasion. …”
Publicado 2020
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2879“…The cellular and subcellular changes that drive color change and how they are orchestrated have been barely understood, but a deeper knowledge of the underlying processes is important to our understanding of how such plastic changes develop and evolve. …”
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2880por Rodrigues, Armanda V., Alexandre-Pires, Graça, Valério-Bolas, Ana, Santos-Mateus, David, Rafael-Fernandes, Mariana, Pereira, Maria A., Ligeiro, Dário, Nunes, Telmo, Alves-Azevedo, Raquel, Santos, Marcos, Pereira da Fonseca, Isabel, Santos-Gomes, Gabriela“…It is therefore suggested that hepatocytes are key effector cells and can activate and orchestrate the immune response to L. infantum parasites.…”
Publicado 2020
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