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2941
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2942Oxidatively stressed extracellular microenvironment drives fibroblast activation and kidney fibrosispor Li, Li, Lu, Meizhi, Peng, Yiling, Huang, Junxin, Tang, Xiaoman, Chen, Jian, Li, Jing, Hong, Xue, He, Meizhi, Fu, Haiyan, Liu, Ruiyuan, Hou, Fan Fan, Zhou, Lili, Liu, Youhua“…These results indicate that loss of GPX3 orchestrates an oxidatively stressed extracellular microenvironment, which promotes fibroblast activation and proliferation through a cascade of signal transduction. …”
Publicado 2023
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2943por Hameroff, Stuart“…The quantum computations are “orchestrated” by synaptic inputs and memory (thus “Orch OR”). …”
Publicado 2012
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2944por Gunewardena, Sumedha S., Yoo, Byunggil, Peng, Lai, Lu, Hong, Zhong, Xiaobo, Klaassen, Curtis D., Cui, Julia Yue“…However, little is known on a transcriptome level of the genes and RNA-splicing variants that are differentially regulated with age, and which up-stream regulators orchestrate age-specific biological functions in liver. …”
Publicado 2015
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2945“…The Target of Rapamycin Complex I (TORC1) orchestrates global reprogramming of transcriptional programs in response to myriad environmental conditions, yet, despite the commonality of the TORC1 complex components, different TORC1-inhibitory conditions do not elicit a uniform transcriptional response. …”
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2946por Xu, Qilin, Zhang, Qunzhou, Ishida, Yasutaka, Hajjar, Souren, Tang, Xudong, Shi, Haoran, Dang, Chi V., Le, Anh D.“…In this study, we explored the role of epidermal growth factor (EGF) in orchestrating Warburg effect, the epithelial-mesenchymal transition (EMT) process, and the acquisition of cancer stem-like cell properties in human oral squamous cell carcinoma (OSCC) cells. …”
Publicado 2016
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2947“…Growing knowledge in gene expression modulation and emerging technologies in drug delivery may soon allow shaping macrophage populations toward orchestrating beneficial rather than detrimental inflammatory responses.…”
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2948por Brossel, Hélène, Fontaine, Alexis, Hoyos, Clotilde, Jamakhani, Majeed, Willems, Mégane, Hamaidia, Malik, Willems, Luc“…These neoantigens are potentially immunogenic and trigger immune responses orchestrated by cytotoxic cells. In malignant mesothelioma (MM), tumor development is nevertheless characterized by a low mutation rate despite major structural chromosomal rearrangements driving oncogenesis. …”
Publicado 2021
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2949“…In this study, flow and MPA have been investigated in 363 orchestral musicians in relation to a particular live music performance. …”
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2950“…They are a specialized lipid domain and orchestrate cellular signaling events, mechanoprotection, and lipid homeostasis. …”
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2951por Burkhardt, Markus, Rapp, Johanna, Menzel, Claudia, Link, Hannes, Forchhammer, Karl“…When nitrogen sources reappear, the cells resuscitate in a process that follows a highly orchestrated program. Here, we describe the essential role of sodium in the resuscitation process. …”
Publicado 2023
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2952por Golubkov, D, Kersevan, B, Klimentov, A, Minaenko, A, Nevski, P, Vaniachine, A, Walker, R“…The system provides knowledge management of configuration parameters for massive data processing tasks, reproducibility of results, scalable database access, orchestrated workflow and performance monitoring, dynamic workload sharing, automated fault tolerance and petascale data integrity control.…”
Publicado 2012
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2953por Spiga, D, Antonacci, M, Boccali, T, Ceccanti, A, Ciangottini, D, Donvito, G, Duma, C, Salomoni, D“…DODAS is built on several INDIGO-DataCloud services among which: the PaaS Orchestrator, the Infrastructure Manager, and the Identity and Access Manager are the most important. …”
Publicado 2018
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2954The Zinc Transporter SLC39A10 Plays an Essential Role in Embryonic Hematopoiesis (Adv. Sci. 17/2023)por He, Xuyan, Ge, Chaodong, Xia, Jun, Xia, Zhidan, Zhao, Lu, Huang, Sicong, Wang, Rong, Pan, Jianwei, Cheng, Tao, Xu, Peng‐Fei, Wang, Fudi, Min, Junxia“…As the most important zinc importer on the cell membrane of hematopoietic stem cells, ZIP10 functions as a gatekeeper (like a vacuum to transport zinc across a cell membrane) for orchestrating zinc acquisition and the fate of stem cells. …”
Publicado 2023
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2955“…Like the conductor of an orchestra, the fields influence each musician or neuron and orchestrate the output, the symphony. Our results use the theory of synergetics, machine learning, and data from a spatial delayed saccade task and provide evidence for in vivo ephaptic coupling in memory representations.…”
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2956“…Cancer immunotherapy, alone or in combination with conventional therapies, has revolutionized the landscape of antineoplastic treatments, with dendritic cells (DC) emerging as key orchestrators of anti-tumor immune responses. Among the distinct DC subsets, conventional type 1 dendritic cells (cDC1) have gained prominence due to their unique ability to cross-present antigens and activate cytotoxic T lymphocytes. …”
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2957“…However, in complex multicellular organisms, the core molecular machinery of autophagy — the 'autophagy proteins' — orchestrates diverse aspects of cellular and organismal responses to other dangerous stimuli such as infection. …”
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2958“…Application of next-generation sequencing technology in the skeletal muscle differentiation field is rapidly extending our knowledge on how chromatin modifications, transcription factors and chromatin regulators orchestrate gene expression pathways guiding myogenesis. …”
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2959por van Dam, Teunis JP, Wheway, Gabrielle, Slaats, Gisela G, Huynen, Martijn A, Giles, Rachel H“…It is therefore essential to orchestrate a well-annotated and high-confidence dataset to be able to assess the quality of any HTP dataset. …”
Publicado 2013
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2960“…Both processes are orchestrated by inflammatory cytokines, including the macrophage migration inhibitory factor (MIF). …”
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