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  1. 2961
    por van Amerongen, Renée
    Publicado 2014
    “…Delineating the mammary stem and progenitor cell hierarchy will provide fundamental knowledge of how cell proliferation and differentiation are orchestrated to build, maintain and regenerate a complex mammalian tissue. …”
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    Bipotent mammary stem cells: now in amazing 3D
  2. 2962
    “…A finely tuned regulatory network orchestrates the biogenesis, maintenance, and turnover of mitochondria. …”
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    Mitochondrial biogenesis and dynamics in the developing and diseased heart
  3. 2963
    “…Terpene cyclization is orchestrated by terpene cyclases, which are involved in the biosynthesis of various cyclic natural products, but understanding the origin and mechanism of the selectivity of terpene cyclization is challenging. …”
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    “Cation-Stitching Cascade”: exquisite control of terpene cyclization in cyclooctatin biosynthesis
  4. 2964
    “…The interplay between oncogenic transformation-driven metabolic re-programming and modulation of aberrant miRNAs further established their critical role in the initiation, promotion and progression of cancer by creating a tumorigenesis-prone microenvironment, thus orchestrating processes of evasion to apoptosis, angiogenesis and invasion/migration, as well metastasis. …”
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    MicroRNA in Metabolic Re-Programming and Their Role in Tumorigenesis
  5. 2965
    por Barra, V., Fachinetti, D.
    Publicado 2018
    “…They have a central role in preventing aneuploidy, by orchestrating the assembly of several components required for chromosome separation. …”
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    The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA
  6. 2966
    por Blume, Martin, Seeber, Frank
    Publicado 2018
    “…T. gondii can replicate in every nucleated host cell by orchestrating metabolic interactions to derive crucial nutrients. …”
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    Metabolic interactions between Toxoplasma gondii and its host
  7. 2967
    “…Calmodulin (CaM) is the principal Ca(2+) sensor in eukaryotic cells, orchestrating the activity of hundreds of proteins. Disease causing mutations at any of the three genes that encode identical CaM proteins lead to major cardiac dysfunction, revealing the importance in the regulation of excitability. …”
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    The Crossroad of Ion Channels and Calmodulin in Disease
  8. 2968
    por Shin, Chong Hyun, Choi, Doo-Sup
    Publicado 2019
    “…In this review, we summarize current data on the functions and molecular mechanisms of TBK1 and IKKε in orchestrating inflammation to cancer, obesity, and diabetes.…”
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    Essential Roles for the Non-Canonical IκB Kinases in Linking Inflammation to Cancer, Obesity, and Diabetes
  9. 2969
    por De Filippo, Katia, Rankin, Sara M.
    Publicado 2018
    “…BACKGROUND: Chemokines play a critical role in orchestrating the distribution and trafficking of neutrophils in homeostasis and disease. …”
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    CXCR4, the master regulator of neutrophil trafficking in homeostasis and disease
  10. 2970
    “…Intimate interactions between photosynthetic and non-photosynthetic organisms require the orchestrated transfer of ions and metabolites between species. …”
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    Understanding transport processes in lichen, Azolla–cyanobacteria, ectomycorrhiza, endomycorrhiza, and rhizobia–legume symbiotic interactions
  11. 2971
    por Lewinski, Martin, Köster, Tino
    Publicado 2018
    “…Proteins that specifically interact with mRNAs orchestrate mRNA processing steps all the way from transcription to decay. …”
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    Systems Approaches to Map In Vivo RNA–Protein Interactions in Arabidopsis thaliana
  12. 2972
    por Reggiori, F., Mauthe, M.
    Publicado 2016
    “…They are formed by the orchestrated interplay of the AuTophaGy-related (ATG) proteins. …”
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    At the Center of Autophagy: Autophagosomes
  13. 2973
    “…It receives information about the environmental light/dark conditions through the eyes and orchestrates peripheral oscillators. Purinergic signaling is mediated by extracellular purines and pyrimidines that bind to purinergic receptors and regulate multiple body functions. …”
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    The Role of Purinergic Receptors in the Circadian System
  14. 2974
    “…Coordination of these cytoskeletal and nuclear events occurs through biochemical regulatory pathways, orchestrated by Cyclin-CDK activity. However, recent studies provide evidence that physical forces are also involved in the early steps of spindle assembly. …”
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    Nucleus-Cytoskeleton Crosstalk During Mitotic Entry
  15. 2975
    “…Protective high affinity antibody responses emerge through an orchestrated developmental process that occurs in germinal centers (GCs). …”
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    Compartments and Connections Within the Germinal Center
  16. 2976
    por Ren, Jie, Miao, Danxiu, Li, Yanshu, Gao, Rui
    Publicado 2021
    “…Cardiac transcription factors orchestrate a regulatory network controlling cardiovascular development. …”
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    Spotlight on Isl1: A Key Player in Cardiovascular Development and Diseases
  17. 2977
    “…The developed algorithms allow identification of interactions between key proteins and predict new actors orchestrating fibroblast activation linked to fibrosis in mouse and human tissues. …”
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    Fibrosis Protein-Protein Interactions from Google Matrix Analysis of MetaCore Network
  18. 2978
    “…This review will focus on innate cell populations involved in the initial phase of this orchestrated process, including innate cells from both the skin and the immune system.…”
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    Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
  19. 2979
    por Kalo, Eric, Read, Scott, Ahlenstiel, Golo
    Publicado 2022
    “…We focus on small molecules and key transcriptional regulators that orchestrate phenotypic conversion and maintenance of engineered cells.…”
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    Reprogramming—Evolving Path to Functional Surrogate β-Cells
  20. 2980
    “…The progression from these underlying liver disease to cancer is accompanied by chronic inflammatory conditions in which liver macrophages play important roles in orchestrating the inflammatory response. During this process, bioactive lipids produced by hepatocytes and macrophages mediate the inflammatory responses by acting as pro-inflammatory factors, as well as, playing roles in the resolution of inflammation conditions. …”
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    Eicosanoids and other oxylipins in liver injury, inflammation and liver cancer development
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