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2981“…Here, we review evidence regarding the possible role of the cerebellum in anxiety—ranging from clinical studies to experimental manipulation of neural activity—that collectively points toward a role for the cerebellum, and possibly a specific topographical locus within the cerebellum, as one of the orchestrators of anxiety responses.…”
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2987por Guan, Wen“…--HTML-->The intelligent Data Delivery Service (iDDS) has been developed to cope with the huge increase of computing and storage resource usage in the coming LHC data taking. iDDS has been designed to intelligently orchestrate workflow and data management systems, decoupling data pre-processing, delivery, and main processing in various workflows. …”
Publicado 2021
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2988por Bocchi, Enrico“…Sciencebox has been tested and deployed on a variety of infrastructures, ranging from tiny deployments on developers' laptops to orchestrated Kubernetes clusters on commercial cloud providers with GPU accelerators and 100s of TBs of storage.…”
Publicado 2022
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2989por Elouni, Hadhami“…This complexity arises primarily from the necessity to adeptly navigate and orchestrate a sprawling and perpetually shifting labyrinth of contacts and information. …”
Publicado 2023
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2990“…Gene expression network in cancer cells is orchestrated by a small number of master regulator transcription factors (MRTFs), which play a prominent role in regulating cancer intrinsic hallmarks, such as sustaining proliferative signaling, evading growth suppressors, resisting cell death, etc. …”
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2991por Fraser, James, Rousseau, Mathieu, Shenker, Solomon, Ferraiuolo, Maria A, Hayashizaki, Yoshihide, Blanchette, Mathieu, Dostie, Josée“…One of the major genomics challenges is to better understand how correct gene expression is orchestrated. Recent studies have shown how spatial chromatin organization is critical in the regulation of gene expression. …”
Publicado 2009
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2992por Russell, Kevin L, Rubenstein, Jennifer, Burke, Ronald L, Vest, Kelly G, Johns, Matthew C, Sanchez, Jose L, Meyer, William, Fukuda, Mark M, Blazes, David L“…This mission is accomplished by orchestrating a global portfolio of surveillance projects, capacity-building efforts, outbreak investigations and training exercises. …”
Publicado 2011
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2993“…Hematopoietic development is orchestrated by gene regulatory networks that progressively induce lineage-specific transcriptional programs. …”
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2994“…Chemokines are a large family of small cytokines that orchestrate cell migration in health and disease. Herein, we have surveyed the genomes of 18 representative vertebrate species for chemokine genes and identified a total of 553 genes. …”
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2995“…We also discuss the biological importance of robust pericentromeric cohesion and early centromere replication, as well as the mechanisms orchestrating these two functions at the microtubule attachment site.…”
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2996“…Adipo(cyto)kines are mostly produced by adipose tissue and orchestrate the adverse impact of excess adiposity on cardiovascular risk. …”
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2997“…The engagement of different Toll-like receptor (TLR) ligands leads to quantitatively and qualitatively unique cytokine production, showing that TLR pathway crosstalk enables the innate immune system to orchestrate immediate local and global responses. It is likely that multiple pathways are involved in the regulation of cytokine synergy, including many that have yet to be discovered.…”
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2998por Wu, Andrew H., He, Li, Long, Wei, Zhou, Qiuping, Zhu, Shu, Wang, Ping, Fan, Saijun, Wang, Haichao“…In response to microbial infections, HMGB1 is secreted from activated immune cells to orchestrate rigorous inflammatory responses. Here we review the distinct mechanisms by which several herbal components inhibit HMGB1 action or secretion, such as by modulating inflammasome activation, autophagic degradation, or endocytic uptake. …”
Publicado 2015
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2999por Matsumoto, Kouji, Hara, Hiroshi, Fishov, Itzhak, Mileykovskaya, Eugenia, Norris, Vic“…This heterogeneity results mainly from lipid–lipid, protein–protein, and lipid–protein associations which are orchestrated by the coupled transcription, translation and insertion of nascent proteins into and through membrane (transertion). …”
Publicado 2015
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3000“…Cardiac transcription factors orchestrate the complex cellular and molecular events required to produce a functioning heart. …”
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