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  1. 3121
    “…In the face of an assault, host cells mount an immediate response orchestrated by innate immunity. Two of the best described innate immune signaling networks are the Toll- and the Nod-like receptor pathways. …”
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    Deviant Behavior: Tick-Borne Pathogens and Inflammasome Signaling
  2. 3122
    “…Hypoxia-inducible factor 1 alpha (HIF-1α) orchestrates cellular adaptation to low oxygen and nutrient-deprived environment and drives progression to malignancy in human solid cancers. …”
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    Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer
  3. 3123
    “…HSP90 and its co-chaperones orchestrate crucial physiological processes such as cell survival, cell cycle control, hormone signaling, and apoptosis. …”
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    The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease
  4. 3124
    “…Cell migration is a highly orchestrated cellular event that involves physical interactions of diverse subcellular components. …”
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    Recapitulation of molecular regulators of nuclear motion during cell migration
  5. 3125
    por Xu, Tao, Guo, Yu, Qi, Xiaopeng
    Publicado 2019
    “…Ubiquitination is an important post-translational modification for orchestrating inflammatory immune responses during pathogenic infection, and a major target hijacked by pathogenic bacteria for promoting their survival and proliferation. …”
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    Ubiquitination-Mediated Inflammasome Activation during Bacterial Infection
  6. 3126
    “…The environment surrounding stem cells has the ability to elicit profound, heritable epigenetic changes orchestrated by multiple epigenetic mechanisms, which can be modulated by the level of specific metabolites. …”
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    Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance
  7. 3127
    “…The catalytic generation of hypervalent iodine(III) reagents by anodic electrooxidation was orchestrated towards an unprecedented electrocatalytic C−H oxygenation of weakly coordinating aromatic amides and ketones. …”
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    C−H Oxygenation Reactions Enabled by Dual Catalysis with Electrogenerated Hypervalent Iodine Species and Ruthenium Complexes
  8. 3128
    por Detrick, Barbara, Hooks, John J.
    Publicado 2019
    “…In fact, the RPE cell orchestrates both innate and adaptive immunity and contains a plethora of factors to regulate the immune response. …”
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    The RPE Cell and the Immune System
  9. 3129
    por Garcia, Esther, Ismail, Shehab
    Publicado 2020
    “…In a signaling network, not only the functions of molecules are important but when (temporal) and where (spatial) those functions are exerted and orchestrated is what defines the signaling output. To temporally and spatially modulate signaling events, cells generate specialized functional domains with variable lifetime and size that concentrate signaling molecules, enhancing their transduction potential. …”
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    Spatiotemporal Regulation of Signaling: Focus on T Cell Activation and the Immunological Synapse
  10. 3130
    “…Through the careful review of records, a well-orchestrated inpatient evaluation, genomic sequencing and testing, and with the use of emerging strategies such as matchmaking programs, the UDP succeeds nearly 30 percent of the time for these highly selective cases. …”
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    The undiagnosed diseases program: Approach to diagnosis
  11. 3131
    “…Glial cells play a central role in orchestrating these neuroinflammation processes in both deleterious and beneficial ways. …”
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    Glia Crosstalk in Neuroinflammatory Diseases
  12. 3132
    “…Mitochondria are dynamic organelles that have essential metabolic activity and are regarded as signalling hubs with biosynthetic, bioenergetics and signalling functions that orchestrate key biological pathways. However, mitochondria can influence all processes linked to oncogenesis, starting from malignant transformation to metastatic dissemination. …”
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    Cancer metabolism and mitochondria: Finding novel mechanisms to fight tumours
  13. 3133
    “…Strikingly, they illustrated that catalysis is orchestrated by a negatively charged radical, α-FAD, that inhibits further reductions and features an atypical inverted kinetic isotope effect. …”
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    A lonely electron blocks incoming pairs
  14. 3134
    por Mo, Fan-E
    Publicado 2021
    “…Here, we discuss how hemodynamic changes orchestrate the remodeling of extracellular microenvironments and the expression profile of the integrin receptors in endothelial cells leading to oxidative stress and inflammation. …”
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    Shear-Regulated Extracellular Microenvironments and Endothelial Cell Surface Integrin Receptors Intertwine in Atherosclerosis
  15. 3135
    por Lee, Jinyoung, Cho, Yongcheol
    Publicado 2021
    “…Axon regeneration is orchestrated by many genes that are differentially expressed in response to injury. …”
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    Potential roles of stem cell marker genes in axon regeneration
  16. 3136
    “…Ocular morphogenesis in vertebrates is a highly organized process, orchestrated largely by intrinsic genetic programs that exhibit stringent spatiotemporal control. …”
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    Genetics and therapy for pediatric eye diseases
  17. 3137
    “…In the human embryo, the genetic program that orchestrates germ cell specification involves the activation of epigenetic and transcriptional mechanisms that make the germline a unique cell population continuously poised between germness and pluripotency. …”
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    To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm
  18. 3138
    “…The hormone abscisic acid (ABA) orchestrates the plant stress response and regulates sophisticated metabolic and physiological mechanisms essential for survival in a changing environment. …”
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    An Update on Crop ABA Receptors
  19. 3139
    “…While their eponymous ATP-binding cassette in the nucleotide-binding domains (NBDs) is highly conserved, their transmembrane domains (TMDs) forming the translocation pathway exhibit distinct folds and topologies, suggesting that during evolution the ancient motor domains were combined with different transmembrane mechanical systems to orchestrate a variety of cellular processes. In recent years, it has become increasingly evident that the distinct TMD folds are best suited to categorize the multitude of ABC transporters. …”
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    Structural and functional diversity calls for a new classification of ABC transporters
  20. 3140
    por Huang, Wanqiu, Wang, Danni, Yao, Yu-Feng
    Publicado 2021
    “…Infections are highly orchestrated and dynamic processes, which involve both pathogen and host. …”
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    Understanding the pathogenesis of infectious diseases by single-cell RNA sequencing
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