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3161“…The paper explains also how TREC has evolved over time from its original main focus on traceability aspects to now also orchestrating several different workflows.…”
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3162“…Cytokines are potent molecules that function as growth factors and orchestrate both innate and adaptive immune responses. …”
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3163por Schnoor, Ulrike, Bührer, Felix, Fischer, Frank, Fleig, Georg, Gamel, Anton, Giffels, Manuel, Hauth, Thomas, Janczyk, Michael, Meier, Konrad, Quast, Günter, Roland, Benoît, Schumacher, Markus, von Suchodoletz, Dirk, Wiebelt, Bernd“…A cloud computing infrastructure is deployed at NEMO to orchestrate the simultaneous usage by bare metal and virtualized jobs. …”
Publicado 2018
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3164“…The heterogenous dynamics of lipids and proteins in the plasma membrane play important roles in regulating cellular activities with an intricate pathway that orchestrates reception, signal transduction and appropriate response in the plant immune system. …”
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3165por Calderon, Jhon Jairo, Prieto, Karol, Lasso, Paola, Fiorentino, Susana, Barreto, Alfonso“…One of the most important groups of cells that orchestrate immunosuppression in TME is myeloid-derived suppressor cells (MDSCs), which have multiple mechanisms to suppress the immune response mediated by T lymphocytes and thus protect the tumor. …”
Publicado 2023
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3166“…Cells/organisms trigger appropriate signal transduction pathways in order to turn on or off intracellular gene expression in response to environmental stimuli. An orchestrated regulation of different signaling pathways across different organs and tissues is the basis of many important biological functions. …”
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3167“…[Image: see text] Molecular proximity orchestrates biological function, and blocking existing proximities is an established therapeutic strategy. …”
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3168por Kannan, Subburaj“…CONCLUSION: It is suggested that the evolution of multi drug resistance is a developmentally orchestrated event. Identifying stage-specific time windows during this process would help to identify valid therapeutic targets for the effective elimination of malignancy.…”
Publicado 2005
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3169“…In addition, SNARE complex assembly is likely orchestrated by Munc13s and RIMs, active-zone proteins that function in vesicle priming and diverse forms of presynaptic plasticity. …”
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3170“…We are gaining an increasingly detailed picture of its regulation during anaphase, and of the way it orchestrates ordered progression through mitosis. Much less is known about protein dephosphorylation during mitotic exit in organisms other than budding yeast, but evidence is now mounting for crucial contributions of regulated phosphatases also in metazoan cells.…”
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3171“…Accumulating evidence indicates that antigen-specific Th2 cells and their cytokines such as IL-4, IL-5, and IL-13 orchestrate these pathognomonic features of asthma. …”
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3172“…Plasmacytoid Dendritic Cells (pDCs) are important immune orchestrators in heart and vessels. They highly produce IFN type I that promote the polarization of T cells towards a Th1 phenotype; however, pDCs can also participate to suppressive networks via the recruitment of T regulatory cells that downmodulate proinflammatory responses. pDCs populate the vessel wall layers during pathological conditions, such as atherosclerosis. …”
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3173“…Intra- and inter-species (bacteria: bacteria) and inter-kingdom (bacteria: host) communication orchestrates the complex relationship among symbiotic microbes, invading pathogens, and their mammalian host. …”
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3174“…Establishing the quiescent state while maintaining the capacity to re-enter the proliferation cycle are critical for cell survival and must be tightly orchestrated to avoid pathological proliferation. Hence, studying the biology of quiescent cells is an exciting research field. …”
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3175por Keightley, Maria-Cristina, Layton, Judith E., Hayman, John W., Heath, Joan K., Lieschke, Graham J.“…Hematopoiesis requires the spatiotemporal organization of regulatory factors to successfully orchestrate diverse lineage specificity from stem and progenitor cells. …”
Publicado 2011
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3176“…During inflammation leukocytes undergo sequential adhesive interactions with endothelial cells to migrate into the inflamed tissues, a process known as the “leukocyte recruitment cascade” which is orchestrated by precise adhesion molecule expression on the cell surface of leukocytes and the endothelium. …”
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3177por Shvedova, Anna A., Kapralov, Alexandr A., Feng, Wei Hong, Kisin, Elena R., Murray, Ashley R., Mercer, Robert R., St. Croix, Claudette M., Lang, Megan A., Watkins, Simon C., Konduru, Nagarjun V., Allen, Brett L., Conroy, Jennifer, Kotchey, Gregg P., Mohamed, Bashir M., Meade, Aidan D., Volkov, Yuri, Star, Alexander, Fadeel, Bengt, Kagan, Valerian E.“…Our results provide direct evidence for the participation of MPO – one of the key-orchestrators of inflammatory response – in the in vivo pulmonary oxidative biodegradation of SWCNT and suggest new ways to control the biopersistence of nanomaterials through genetic or pharmacological manipulations.…”
Publicado 2012
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3178“…We also discuss the action of specific miRNAs and RBPs that are direct transcriptional targets of p53 and how they act coordinately with protein-coding p53 target genes to orchestrate p53-dependent cellular responses.…”
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3179“…We recently identified the transcriptional network that orchestrates the formation of biofilms in C. albicans. …”
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3180por Boasso, Adriano“…They actively participate in antiviral immunity by inducing molecular mechanisms of viral restriction and by limiting the spread of the infection, but they also orchestrate the initial phases of the adaptive immune response and influence the quality of T cell immunity. …”
Publicado 2013
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