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  1. 3181
    por Lillington, James, Waksman, Gabriel
    Publicado 2013
    “…Pilus formation and secretion are orchestrated by two accessory proteins, a chaperone, which catalyses pilus subunit folding and maintains them in a polymerization-competent state, and an outer membrane-spanning nanomachine, the usher, which choreographs their assembly into a pilus and drives their secretion through the membrane. …”
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    Ordered and Ushered; the Assembly and Translocation of the Adhesive Type I and P Pili
  2. 3182
    “…Hence, pyruvate modulates E. coli glycogen metabolism by orchestrating a functional network of allosteric regulators. …”
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    A Novel Dual Allosteric Activation Mechanism of Escherichia coli ADP-Glucose Pyrophosphorylase: The Role of Pyruvate
  3. 3183
    por Mollereau, Bertrand, Ma, Dali
    Publicado 2014
    “…In the presence of acute DNA-damage, oncogene deregulation and other forms of cellular stress, p53 orchestrates a myriad of pleiotropic processes to repair cellular damages and maintain homeostasis. …”
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    The p53 control of apoptosis and proliferation: lessons from Drosophila
  4. 3184
    “…MicroRNAs (miRNAs) have emerged as potent modulators of mammalian gene expression, thereby broadening the spectrum of molecular mechanisms orchestrating human physiological and pathological cellular functions. …”
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    MicroRNAs in heart failure: Small molecules with major impact
  5. 3185
    por Shu, Jian, Deng, Hongkui
    Publicado 2013
    “…Recently, lineage specifiers have been identified to play important roles in orchestrating the process of restoring pluripotency. …”
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    Lineage Specifiers: New Players in the Induction of Pluripotency
  6. 3186
    “…As in other organs, macrophages and dendritic cells (DCs) orchestrate in addition the immune defense against pathogens, both in lymph nodes and mucosa-associated lymphoid tissue. …”
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    Guardians of the Gut – Murine Intestinal Macrophages and Dendritic Cells
  7. 3187
    “…Recent advances in the understanding of the molecular, cellular and epigenetic mechanisms that orchestrate plant responses to abiotic stress will serve as the platform to engineer improved crop plants with better designed root system architecture and optimized metabolism to enhance water and nutrients uptake and use efficiency and/or soil penetration. …”
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    Engineering food crops to grow in harsh environments
  8. 3188
    por Shakhar, Keren, Shakhar, Guy
    Publicado 2015
    “…SB affects species spanning from arthropods to vertebrates, is triggered nonspecifically by viruses, bacteria, and parasites, and is orchestrated by a complex network of cytokines and neuroendocrine pathways; clearly, it has been naturally selected. …”
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    Why Do We Feel Sick When Infected—Can Altruism Play a Role?
  9. 3189
    por Shin, Jung Eun, Cho, Yongcheol
    Publicado 2017
    “…In this article, we review recent studies on the epigenetic mechanisms orchestrating changes in gene expression in response to nerve injury. …”
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    Epigenetic Regulation of Axon Regeneration after Neural Injury
  10. 3190
    “…After providing a general overview of the mechanisms controlling autophagosome biogenesis and cell migration, we discuss how chemotactic G protein-coupled receptors, through the repression of autophagy, may orchestrate membrane trafficking and compartmentation of specific proteins at the cell front in order to support the critical steps of directional migration.…”
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    The Autophagy Machinery: A New Player in Chemotactic Cell Migration
  11. 3191
    “…These advancements in preclinical and clinical studies suggest that LDR-mediated immune modulation is a well-orchestrated phenomenon with clinical potential. We summarize recent developments in the understanding of LDR-mediated immune modulation, with an emphasis on its potential clinical applications.…”
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    Hormetic Response to Low-Dose Radiation: Focus on the Immune System and Its Clinical Implications
  12. 3192
    por Moran-Salvador, Eva, Mann, Jelena
    Publicado 2017
    “…Although genetic influences are important, it is epigenetic mechanisms that have been shown to orchestrate many aspects of fibrogenesis in the liver. …”
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    Epigenetics and Liver Fibrosis
  13. 3193
    por Yang, Wenjun, Hu, Ping
    Publicado 2018
    “…Skeletal muscle regeneration is a complex process orchestrated by multiple steps. Recent findings indicate that inflammatory responses could play central roles in bridging initial muscle injury responses and timely muscle injury reparation. …”
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    Skeletal muscle regeneration is modulated by inflammation
  14. 3194
    por Bastide, Amandine, David, Alexandre
    Publicado 2018
    “…Recent findings have shifted this obsolete view, revealing a remarkably complex and multifaceted machinery whose role is to orchestrate spatiotemporal control of gene expression. …”
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    The ribosome, (slow) beating heart of cancer (stem) cell
  15. 3195
    “…We show that nuclear factor κB orchestrates a multi-faceted metabolic program necessary for the maturation of neural progenitor cells during neurogenesis.…”
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    NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program
  16. 3196
    “…Recent studies have identified critical roles of metabolic pathways, including glycolysis, oxidative phosphorylation, and fatty acid metabolism, in orchestrating DC function. In this review, we discuss the shared and distinct metabolic programs shaping the functional specification of different DC subsets, including conventional DCs, bone marrow-derived DCs, and plasmacytoid DCs. …”
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    Emerging Roles of Cellular Metabolism in Regulating Dendritic Cell Subsets and Function
  17. 3197
    “…This paper focuses on the molecular mechanisms and signaling pathways responsible for the transactivation of genes encoding for these proteins, as orchestrated by a series of transcription factors and related signaling components.…”
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    Transactivation of Genes Encoding for Phase II Enzymes and Phase III Transporters by Phytochemical Antioxidants
  18. 3198
    por Wong, David CS, O’Neill, John S
    Publicado 2018
    “…‘Biological clocks’ orchestrate mammalian biology to a daily rhythm. Whilst ‘clock gene’ transcriptional circuits impart rhythmic regulation to myriad cellular systems, our picture of the biochemical mechanisms that determine their circadian (∼24 hour) period is incomplete. …”
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    Non-transcriptional processes in circadian rhythm generation
  19. 3199
    “…Like many developmental processes, a large number of transcription factors, such as homeobox genes, have been shown to orchestrate this complicated but highly organized physiological process during implantation. …”
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    Homeobox genes for embryo implantation: From mouse to human
  20. 3200
    “…The extracellular matrix (ECM) of endothelial cells, also known as the perivascular matrix, forms an organ specific vascular niche that orchestrates mechano‐, growth factor, and angiocrine signaling required for tissue homeostasis and organ repair. …”
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    Concise Review: The Endothelial Cell Extracellular Matrix Regulates Tissue Homeostasis and Repair
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