“…Recent advance in glycoproteomics, glycomics and other chemical biology techniques have been employed to better understand the complex mechanism of glycosylation events and how they orchestrate molecular activities in genomics, proteomics and metabolomics implicated in pancreatic adenocarcinoma. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this review, we aim to highlight how these kinases cooperate to orchestrate diverse processes during cellular reproduction, focusing on meiosis-specific adaptions of their regulation and functions in DNA metabolism.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The wound healing process is a highly orchestrated series of mechanisms where a multitude of cells and biological cascades are involved. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We review here the latest breakthroughs in our understanding of the post-transcriptional processes of mitochondrial gene expression, focusing on advances in analyzing the mitochondrial epitranscriptome, the role of mitochondrial RNA granules (MRGs), the benefits of recently obtained structures of the mitochondrial ribosome, and the coordination of mitochondrial and cytosolic translation to orchestrate the biogenesis of OxPhos complexes.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The suprachiasmatic nucleus (SCN), in the ventral part of the anterior hypothalamus, orchestrates physiological and behavioral circadian rhythms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recent discoveries are revealing that these same ATGs orchestrate processes that are related to, and yet clearly distinct from, classic autophagy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore it is now well appreciated that a novel group of autacoids termed as specialized proresolving mediators, which are enzymatically produced from essential fatty acids, orchestrate the immune response promoting the termination of inflammation as well as tissue repair and regeneration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mesoderm derived cells gives rise to 700 unique muscles in humans as a result of well-orchestrated signaling and transcriptional networks in specific time and space. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Chromatin loops and topological domains form the basic structural units of this multiscale organization and are essential to orchestrate complex regulatory networks and transcription mechanisms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recent research has uncovered key mechanisms of translational control that are orchestrated by circadian rhythmicity and in turn feed back to the clock machinery to maintain robustness and accuracy of circadian timekeeping. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recent studies on the underlying biology of AD in cellular and animal models have indicated that p38 MAPK is capable of orchestrating diverse events related to AD, such as tau phosphorylation, neurotoxicity, neuroinflammation and synaptic dysfunction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The evolutionarily conserved family of proteins called caspases are the main factors mediating the orchestrated programme of cell suicide known as apoptosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We conclude that MYC proteins orchestrate a rewiring of somatic cell metabolism early in cell reprogramming, whereby somatic cells acquire the phenotypic plasticity necessary for their transition to pluripotency in response to either intrinsic or external cues.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Rac proteins function downstream of receptor tyrosine kinases, chemokine receptors, and integrins, orchestrating a multitude of signals arising from the microenvironment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In Gram‐negative bacteria, the process of conjugation is mediated by a large membrane‐embedded machinery termed “conjugative type IV secretion (T4S) system”, a large injection nanomachine, which together with a DNA‐processing machinery termed “the relaxosome” and a large extracellular tube termed “pilus” orchestrates directional DNA transfer. Here, the focus is on past and latest research in the field of conjugation and T4S systems in Gram‐negative bacteria, with an emphasis on the various questions and debates that permeate the field from a mechanistic perspective.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Herein, we describe recent insights into the biology of ADP-ribose erasers and discuss the intricately orchestrated cellular processes to switch off ADP-ribose-dependent mechanisms.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Beyond fuel metabolism, adipocytes communicate with the immune system and other tissues by releasing diverse paracrine and endocrine factors to orchestrate adipose tissue remodeling and maintain systemic homeostasis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we report the crystal structure of NuMA:LGN hetero-hexamers, and unveil their role in promoting the assembly of active cortical dynein/dynactin motors that are required in orchestrating oriented divisions in polarized cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Monopolar spindle 1 (Mps1) is a dual‐specificity protein kinase, orchestrating faithful chromosome segregation during mitosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This is workflow is a case study on how to use the CAGEfightR package to orchestrate analysis of CAGE data within the Bioconductor project. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso