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3281por Singh, Navjot, Gallagher, Heather C., Song, Renjie, Dhinsa, Jaskiran K., Ostroff, Gary R., De Jesus, Magdia“…Sampling and immune surveillance within gut-associated lymphoid tissues such as the intestinal Peyer’s patch (PP) occurs by an elegantly orchestrated effort that involves the epithelial barrier, B and T lymphocytes, and an extensive network of mononuclear phagocytes. …”
Publicado 2018
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3282“…As dendritic cells (DCs) orchestrate antiviral immune responses, they are in the focus of research analysing hantavirus-induced immunopathogenesis. …”
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3283“…Mitochondria are cellular organelles that orchestrate a vast range of biological processes, from energy production and metabolism to cell death and inflammation. …”
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3284“…Due to their bacterial origin, mitochondria possess their own genome and carry unique lipid components that endow these organelles with specialized properties to help orchestrate multiple signaling cascades. Mitochondrial signaling modulates diverse pathways ranging from metabolism to redox homeostasis to cell fate determination. …”
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3285“…The mammalian hair follicle undergoes repeated bouts of regeneration orchestrated by a variety of hair follicle stem cells. …”
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3286por Sim, Fiona“…Early, rapid, nationally orchestrated vaccine rollout has been a feature in the response to the global coronavirus pandemic in Israel and the UK, two countries with long established, universal socialised health care systems. …”
Publicado 2021
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3287“…Axonal trajectories and neural circuit activities strongly rely on a complex system of molecular cues that finely orchestrate the patterning of neural commissures. Several of these axon guidance molecules undergo continuous recycling during brain development, according to incompletely understood intracellular mechanisms, that in part rely on endocytic and autophagic cascades. …”
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3288por Dlugosz, Paula, Teufl, Magdalena, Schwab, Maximilian, Kohl, Katharina Eva, Nimpf, Johannes“…Disabled 1 (Dab1) is an adapter protein for very low density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2) and an integral component of the Reelin pathway which orchestrates neuronal layering during embryonic brain development. …”
Publicado 2021
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3289“…These surveillance mechanisms are particularly crucial during meiotic prophase, when cells execute a highly orchestrated program of chromosome morphogenesis and recombination, which must be integrated with the meiotic cell division machinery to ensure the safe execution of meiosis. …”
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3290“…Combinatorial action and crosstalk of external and internal signals is the key to cellular heterogeneity, often converging on transcription factors that orchestrate gene expression programs.…”
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3291“…However, evolving evidences suggest that neutrophils also contribute to tissue repair and actively orchestrate resolution of inflammation. Here, we addressed the complex roles in APAP‐induced liver injury on the basis of brief introduction of neutrophil's activation, recruitment and migration.…”
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3292“…Among various molecules in perineural niche, microRNA (miRNA) as an emerging modulator of PNI through generating RNA-induced silencing complex (RISC) to orchestrate oncogene and anti-oncogene has aroused a wide attention. …”
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3293“…Though T cells are believed to orchestrate disease, the type of T cell and the location and mechanism of T cell activation remain unknown. …”
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3294“…In addition, EMT is increasingly understood to orchestrate a large variety of complementary cancer features, such as tumor cell stemness, tumorigenicity, resistance to therapy and adaptation to changes in the microenvironment. …”
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3295por Cen, Xiao, Pan, Xuefeng, Zhang, Bo, Huang, Wei, Xiong, Xiner, Huang, Xinqi, Liu, Jun, Zhao, Zhihe“…Mechanosensitive ncRNAs could convert various physical forces into biochemical signals, and orchestrate signaling networks that regulate the osteogenic differentiation of MSCs in their unique microenvironment. …”
Publicado 2021
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3296“…Gene splicing is a fine-tuned process orchestrated by splice factors including RNA-binding motif 20 (RBM20), and their mutations are linked to the development of cardiac diseases. …”
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3297“…The decellularized scaffold preserves the original orchestral structure and bioactive chemicals of the liver, and has the potential to create a de novo liver that is fit for transplantation after recellularization. …”
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3298por Pulcu, Erdem, Guinea, Calum, Cowen, Philip J., Murphy, Susannah E., Harmer, Catherine J.“…In this Perspective article, we synthesise the recent evidence from rodent, monkey and human neuroimaging literature to highlight how the habenula, a small evolutionarily conserved subcortical structure located in the midbrain, may orchestrate the behavioural expression of anhedonia across fronto-mesolimbic networks. …”
Publicado 2021
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3299“…Initial research has described their critical role in tissue homeostasis and in orchestrating cellular communication to allow respiration. …”
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3300“…B-cell development is a very orchestrated pathway that involves several molecules, such as transcription factors, cytokines, microRNAs, and also different cells. …”
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