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  1. 3301
    “…Hypoxia and hypoxia-inducible factors (HIFs) are essential in regulating several cellular processes, such as survival, differentiation, and the cell cycle; this adaptation is orchestrated in a complex way. In this review, we focused on the impact of hypoxia in the physiopathology of idiopathic pulmonary fibrosis (IPF) related to lung development, regeneration, and repair. …”
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    Functional Repercussions of Hypoxia-Inducible Factor-2α in Idiopathic Pulmonary Fibrosis
  2. 3302
    “…Circadian clocks orchestrate daily rhythms in many organisms and are essential for optimal health. …”
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    Online Artículo Texto
    A broken circadian clock: The emerging neuro-immune link connecting depression to cancer
  3. 3303
    “…Innate and adaptive immune cells are found in distinct tissue niches where they orchestrate immune responses. This requires intrinsic and temporal metabolic adaptability to coordinately activate the immune response cascade. …”
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    Metabolic features of innate lymphoid cells
  4. 3304
    “…SETD2-induced methylation blocks Trim21-mediated ubiquitination and degradation, preserving autophagy activity. SETD2 and Trim21 orchestrate FIP200 protein stability to achieve dynamic and precise control of autophagy flux.…”
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    FIP200 Methylation by SETD2 Prevents Trim21-Induced Degradation and Preserves Autophagy Initiation
  5. 3305
    “…Adipogenesis is a tightly orchestrated multistep process wherein preadipocytes differentiate into adipocytes. …”
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    Chaperone-mediated autophagy regulates adipocyte differentiation
  6. 3306
    “…Thousands of RNA-binding proteins orchestrate RNA processing and altered protein-RNA interactions frequently lead to disease. …”
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    Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq
  7. 3307
    “…Mitofusin 2 is an essential large GTPase protein that orchestrates fusion of outer mitochondria membranes, and mutations in the encoding gene are causative for Charcot-Marie-Tooth disease. …”
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    Novel putative interactors of FZO-1/mitofusin 2 identified using large-scale yeast two-hybrid screening in C. elegans
  8. 3308
    por Nevalainen, Susanna
    Publicado 2018
    “…Post Mortem Framework orchestrates the analysis flow and provides all necessary infrastructure to the analysis modules. …”
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    Post Mortem Web UI Report
  9. 3309
    “…Remarkably, the molecular docking studies demonstrated a prominent affinity score of all these agents together with PI3K, implying the potency of the extract to orchestrate PI3K, which is the predominant signal for lessening the level of blood glucose. …”
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    The Synergistic Influence of Polyflavonoids from Citrus aurantifolia on Diabetes Treatment and Their Modulation of the PI3K/AKT/FOXO1 Signaling Pathways: Molecular Docking Analyses and In Vivo Investigations
  10. 3310
    “…However, the mechanistic role and functional significance of this pathway in orchestrating cellular inflammatory responses to the virus in vivo remain unclear. …”
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    IL-1α and Complement Cooperate in Triggering Local Neutrophilic Inflammation in Response to Adenovirus and Eliminating Virus-Containing Cells
  11. 3311
    “…Dendritic cells (DCs) are endowed with a unique potency to prime T cells, as well as to orchestrate their expansion, functional polarization and effector activity in non-lymphoid tissues or in their draining lymph nodes. …”
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    Are Conventional Type 1 Dendritic Cells Critical for Protective Antitumor Immunity and How?
  12. 3312
    “…CONCLUSIONS: Well-orchestrated assaults on science continue unabated and must now be met head-on. …”
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    Online Artículo Texto
    How can the integrity of occupational and environmental health research be maintained in the presence of conflicting interests?
  13. 3313
    “…These findings suggest that romantic love, and its maintenance, are orchestrated by dopamine-, vasopressin- and oxytocin-rich brain regions, as seen in humans and other monogamous animals. …”
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    After the Honeymoon: Neural and Genetic Correlates of Romantic Love in Newlywed Marriages
  14. 3314
    “…The hypothalamic–pituitary–thyroid (HPT) axis in birds can crosstalk with the hypothalamic–pituitary–gonadal (HPG) axis, thus orchestrating both the reproduction and metabolism. However, until now, how the free-living birds timely optimize both the energy metabolism and reproduction via HPT-axis is not understood. …”
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    Hypothalamic–Pituitary–Thyroid Axis Crosstalk With the Hypothalamic–Pituitary–Gonadal Axis and Metabolic Regulation in the Eurasian Tree Sparrow During Mating and Non-mating Periods
  15. 3315
    “…A typical process orchestrated by miRNAs is the normal B-cell development. …”
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    MicroRNAs: Tiny Regulators of Gene Expression with Pivotal Roles in Normal B-Cell Development and B-Cell Chronic Lymphocytic Leukemia
  16. 3316
    “…These novel aspects suggest that HMOX1 can influence transcriptional and epigenetic modulations to orchestrate OSR affecting cell fate decisions.…”
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    Online Artículo Texto
    Heme Oxygenase-1 at the Nexus of Endothelial Cell Fate Decision Under Oxidative Stress
  17. 3317
    “…SIMPLE SUMMARY: Cell-to-cell communication in the tumor microenvironment is a crucial process to orchestrate the different components of the tumoral infrastructure. …”
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    Online Artículo Texto
    RalGPS2 Interacts with Akt and PDK1 Promoting Tunneling Nanotubes Formation in Bladder Cancer and Kidney Cells Microenvironment
  18. 3318
    “…ABSTRACT: The oncogenic transcription factor ZNF217 orchestrates several molecular signaling networks to reprogram integrated circuits governing hallmark capabilities within cancer cells. …”
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    The Intricate Interplay between the ZNF217 Oncogene and Epigenetic Processes Shapes Tumor Progression
  19. 3319
    “…The capability in predicting the patients without OSAS or with severe OSAS was strong, especially the latter, and the weighted ESS orchestrated manifest improvement in screening the patients with simple snoring. …”
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    Weighted Epworth sleepiness scale predicted the apnea-hypopnea index better
  20. 3320
    “…The ATLAS data acquisition (DAQ) system is controlled and configured via a software infrastructure that takes care of coherently orchestrating the data taking. While the overall architecture, established at the end of the 90’s, has proven to be solid and flexible, many software components have undergone a complete redesign or re-implementation in 2013/2014 in order to fold-in the additional requirements that appeared in the course of LHC’s Run 1, to profit from new technologies and to re-factorise and cleanup software. …”
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    Upgrade of the ATLAS Control and Configuration Software for Run 2
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