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  1. 3341
    por Yu, Michael C.
    Publicado 2011
    “…This process requires a well-orchestrated and dynamic sequence of molecular recognition events by specific RNA-binding proteins. …”
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    The Role of Protein Arginine Methylation in mRNP Dynamics
  2. 3342
    por Esmon, Charles T.
    Publicado 2011
    “…In addition to EPCR orchestrating these changes, CD11b is also capable of supporting APC signaling. …”
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    Protein C anticoagulant system—anti-inflammatory effects
  3. 3343
    “…However, the spectrum of these enzymes orchestrating connective tissue turnover and general biology is much larger than anticipated. …”
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    Matrix metalloproteinases in arthritic disease
  4. 3344
    “…Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis has not been addressed. …”
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    Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response
  5. 3345
    por Zhang, Nu, Bevan, Michael J.
    Publicado 2011
    “…The initial interaction with antigen-presenting cells in the central lymphoid organs drives an orchestrated program of differentiation aimed at producing sufficient numbers of effectors to get the job done without resulting in clonal exhaustion. …”
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    CD8(+) T Cells: Foot Soldiers of the Immune System
  6. 3346
    “…Plaque macrophages orchestrate many of the inflammatory processes that occur throughout atherogenesis. …”
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    Molecular Pathways Regulating Macrophage Polarization: Implications for Atherosclerosis
  7. 3347
    por Millarte, Valentina, Farhan, Hesso
    Publicado 2012
    “…Uncovering the regulatory network that orchestrates cell migration is of fundamental importance for the development of new therapeutic strategies against cancer cell metastasis.…”
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    The Golgi in Cell Migration: Regulation by Signal Transduction and Its Implications for Cancer Cell Metastasis
  8. 3348
    “…Like other enteroendocrine hormones they help to orchestrate the bodies' response to the availability of newly absorbable nutrients and are noteworthy as they stimulate postprandial insulin secretion, underlying what is known as the incretin effect. …”
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    Nutrient detection by incretin hormone secreting cells
  9. 3349
    “…Several inflammatory mediators (including cytokines, chemokines and matrix metalloproteases) have been shown to orchestrate common pathophysiological mechanisms regulating both plaque vulnerability and myocardial injury. …”
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    Update on the Pathophysiological Role of Intracellular Signaling Pathways in Atherosclerotic Plaques and Ischemic Myocardium
  10. 3350
    “…Here, examining both the secretory and the endocytic pathways, we review recent findings illustrating the surprising virtuosity of the KCNE proteins in orchestrating not just the function, but also the composition, diaspora and retrieval of channels formed by their Kv α subunit partners.…”
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    KCNE Regulation of K(+) Channel Trafficking – a Sisyphean Task?
  11. 3351
    “…Sirtuins are one group of environment sensors of a cell interpreting external information and orchestrating internal responses at the sub-cellular level, through participation in gene regulation mechanisms. …”
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    Sirtuins of parasitic protozoa: In search of function(s)
  12. 3352
    “…Stimulation of TLRs by mycobacteria and their antigenic components rapidly induces intracellular signaling cascades involved in the activation of nuclear factor-κB and mitogen-activated protein kinase pathways, which play important roles in orchestrating proinflammatory responses and innate defense through generation of a variety of antimicrobial effector molecules. …”
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    Mycobacterial signaling through toll-like receptors
  13. 3353
    por Shapiro, Rebecca S., Cowen, Leah E.
    Publicado 2012
    “…The myriad of molecular mechanisms by which microbes sense and respond to temperature reveals an elegant repertoire of strategies to orchestrate cellular signaling, developmental programs, and virulence with spatial and temporal environmental cues.…”
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    Thermal Control of Microbial Development and Virulence: Molecular Mechanisms of Microbial Temperature Sensing
  14. 3354
    “…Rhythmic circadian expression of clock-controlled genes is orchestrated by a molecular clock that relies on interconnected negative feedback loops of transcription regulators. …”
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    The Circadian Clock Coordinates Ribosome Biogenesis
  15. 3355
    “…Directional movement of cells in the human body is orchestrated via chemokines. This migration was initially identified in pathological and immunological processes but quickly extended to homeostatic cell trafficking. …”
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    Involvement of CXCR4/CXCR7/CXCL12 Interactions in Inflammatory Bowel Disease
  16. 3356
    por Heidemann, Martin, Eick, Dirk
    Publicado 2012
    “…Dynamic phosphorylation of Ser2, Ser5 and Ser7 residues orchestrates the binding of transcription and RNA processing factors to the transcription machinery. …”
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    Tyrosine-1 and threonine-4 phosphorylation marks complete the RNA polymerase II CTD phospho-code
  17. 3357
    “…In Saccharomyces cerevisiae, the telomeric G-overhang bound Cdc13 acts as a platform for the recruitment of several factors that orchestrate timely transitions between these steps. …”
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    Cdc13 at a crossroads of telomerase action
  18. 3358
    “…Macrophages are professional phagocytic cells that orchestrate innate immune responses and display remarkable phenotypic diversity at different anatomical locations. …”
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    The Nuclear Receptor LXRα controls the functional specialization of splenic macrophages
  19. 3359
    “…Amongst the chemokine signalling axes involved in cancer, chemokine CXCL12 acting on chemokine receptor CXCR4 is particularly significant since it orchestrates migration of cancer cells in a tissue-specific metastatic process. …”
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    Discovery and Computer Aided Potency Optimization of a Novel Class of Small Molecule CXCR4 Antagonists
  20. 3360
    por Wang, Jun, Al-Lamki, Rafia S.
    Publicado 2013
    “…Tumor necrosis factor receptor 2 (TNFR2) is a type I transmembrane glycoprotein and one of the two receptors that orchestrate the complex biological functions of tumor necrosis factor (TNF, also designed TNF-α). …”
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    Tumor Necrosis Factor Receptor 2: Its Contribution to Acute Cellular Rejection and Clear Cell Renal Carcinoma
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