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  1. 3441
    por Wei, Hua-Xing, Wang, Baolong, Li, Bofeng
    Publicado 2020
    “…The barrier surfaces of the gastrointestinal tract are in constant contact with various microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the defense against pathogens. …”
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    IL-10 and IL-22 in Mucosal Immunity: Driving Protection and Pathology
  2. 3442
    “…We revealed that specific localization of auxin transporters at the different membranes of these young cells changes during the course of lobe formation, suggesting that these fluctuating auxin response gradients are orchestrated via auxin transport to control lobe formation and determine pavement cell shape.…”
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    Fluctuating auxin response gradients determine pavement cell-shape acquisition
  3. 3443
    “…In the present review, an effort has been made to orchestrate the fundamental information related to structure, depolymerization characteristics, and classification of pectin as well as the types and biochemical properties of pectinase. …”
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    Biochemical Prospects of Various Microbial Pectinase and Pectin: An Approachable Concept in Pharmaceutical Bioprocessing
  4. 3444
    “…T cell discrimination of self and non-self is the foundation of the adaptive immune response, and is orchestrated by the interaction between T cell receptors (TCRs) and their cognate ligands presented by major histocompatibility (MHC) molecules. …”
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    Genetic and environmental determinants of human TCR repertoire diversity
  5. 3445
    “…Mitigation of risk to frontline providers requires airway management to be an orchestrated exercise based on training and purposeful simulation. …”
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    MIST (Modified Intubating Sequence for Transmissibility) Bundle for Infectious Diseases with Aerosol Hazard
  6. 3446
    “…This is observed in the axons of neurons, where mRNA localization is involved in regulating neuronal development and function by orchestrating rapid adaptive responses to extracellular cues and the maintenance of axonal homeostasis through local translation. …”
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    Molecular mechanisms behind mRNA localization in axons
  7. 3447
    por Li, Jianhua, Bao, Guoqiang, Wang, Haichao
    Publicado 2020
    “…A ubiquitous nuclear protein, HMGB1, is secreted by activated leukocytes to orchestrate inflammatory responses during early stages of sepsis. …”
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    Time to Develop Therapeutic Antibodies Against Harmless Proteins Colluding with Sepsis Mediators?
  8. 3448
    por Wang, Ping, Jia, Jidong, Zhang, Dong
    Publicado 2020
    “…The nucleotide/nucleoside balance orchestrates liver homeostasis, tissue repair, and functional restoration by regulating the crosstalk between liver-resident cells and recruited immune cells. …”
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    Purinergic signalling in liver diseases: Pathological functions and therapeutic opportunities
  9. 3449
    “…Stromal cells (SCs) are strategically positioned in both lymphoid and nonlymphoid organs to provide a scaffold and orchestrate immunity by modulating immune cell maturation, migration and activation. …”
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    Lymph Node Stromal Cells: Mapmakers of T Cell Immunity
  10. 3450
    “…However, there are a few proteins among these groups which impede deleterious effects by orchestrating the pro-apoptotic phenomenon and paving a therapeutic pathway. …”
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    Endogenous Anti-Cancer Candidates in GPCR, ER Stress, and EMT
  11. 3451
    “…Therefore, we discuss approaches to mitigate hyperinflammatory reactions initiated by SARS-CoV2 but orchestrated by immune mediators.…”
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    Perspective: Reducing SARS-CoV2 Infectivity and Its Associated Immunopathology
  12. 3452
    “…Cell–cell interactions orchestrate organismal development, homeostasis and single-cell functions. …”
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    Deciphering cell–cell interactions and communication from gene expression
  13. 3453
    “…It plays a significant role in orchestrating the cytokine cascade, accelerates atherosclerosis and influences plaque vulnerability. …”
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    A Stochastic Petri Net-Based Model of the Involvement of Interleukin 18 in Atherosclerosis
  14. 3454
    por Cai, Chunmei, Hu, Zhiqiang, Yu, Xiao
    Publicado 2020
    “…Here, we summarize our current understanding of host immune responses against Plasmodium-derived components infection and mainly focus on the various regulatory mechanisms mediated by recent identified immune regulators orchestrating anti-malaria immunity.…”
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    Accelerator or Brake: Immune Regulators in Malaria
  15. 3455
    “…In this review, we provide a summary of recent findings that explain how MCs act as a link between the innate and adaptive immunity, all the way from sensing inflammatory insult to orchestrating the final outcome of the immune response.…”
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    Mast Cell Functions Linking Innate Sensing to Adaptive Immunity
  16. 3456
    por Kim, Jungsun
    Publicado 2020
    “…Although genetic mutations are required for cancer development, reversible non-genetic alterations also play a pivotal role in cancer progression. Failure of well-orchestrated gene regulation by chromatin states and master transcription factors can be one such non-genetic etiology for cancer development. …”
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    Cellular reprogramming to model and study epigenetic alterations in cancer
  17. 3457
    “…Remarkably, we showed for the first time the presence of a developmentally regulated network orchestrating glycosylation changes and identified polycomb repressive complex 2 (PRC2) as a key component involved in this process. …”
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    A defined glycosylation regulatory network modulates total glycome dynamics during pluripotency state transition
  18. 3458
    “…Neural communication orchestrates a variety of behaviors, yet despite impressive effort, delineating transmission properties of neuromodulatory communication remains a daunting task due to limitations of available monitoring tools. …”
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    Genetically encoded sensors enable micro- and nano-scopic decoding of transmission in healthy and diseased brains
  19. 3459
    “…This work reveals a direct interaction of gp41 CT with chol and indicates that this interaction is an important orchestrator of Env clustering.…”
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    Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV‐1 Env Clustering
  20. 3460
    “…The expression of pro and anti-inflammatory cytokines and chemokines is crucial in orchestrating the delicate balance that exists between host resistance and tissue pathology. …”
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    Cytokines and splenic remodelling during Leishmania donovani infection
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