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  1. 3581
    “…The three signaling pathways act together in a strictly regulated chronology to orchestrate the development of the entire thalamus.…”
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    The Tale of the Three Brothers – Shh, Wnt, and Fgf during Development of the Thalamus
  2. 3582
    “…We propose that the process results from an unusual interaction between two regulatory systems: the regulatory arm of the immune system (including Bregs) and the tissue repair regulatory components orchestrated by the activated stellate cell. This interaction results in ongoing mutual activation, generating TGFbeta, IL10, and vitamin D. …”
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    IgG4-Related Fibrotic Diseases from an Immunological Perspective: Regulators out of Control?
  3. 3583
    por Sohn, Myung Hyun, Kim, Kyu-Earn
    Publicado 2012
    “…Although allergen-specific adaptive immune responses orchestrate the cockroach allergic response, recent data suggest that the innate immune system is also a critical contributor to pathogenesis. …”
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    The Cockroach and Allergic Diseases
  4. 3584
    “…Mitochondria are membrane bound organelles present in almost all eukaryotic cells. Responsible for orchestrating cellular energy production, they are central to the maintenance of life and the gatekeepers of cell death. …”
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    Cellular and molecular mechanisms of mitochondrial function
  5. 3585
    “…Voltage-gated ion channels are a class of membrane proteins that temporally orchestrate the ion flux critical for chemical and electrical signaling in excitable cells. …”
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    Function of Shaker potassium channels produced by cell-free translation upon injection into Xenopus oocytes
  6. 3586
    por Miano, Joseph M.
    Publicado 2010
    “…This cell type arises throughout the embryo body plan via poorly understood signaling cascades that direct the expression of transcription factors and microRNAs which, in turn, orchestrate the activation of contractile genes collectively defining this cell lineage. …”
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    Vascular smooth muscle cell differentiation-2010
  7. 3587
    “…Considerable attention is focused on the particular role of adaptive immune responses orchestrated by T cell subsets. Since the role of Th1/Th2 balance and Th1 cell domination in atherogenesis is already known, the involvement of regulatory T lymphocytes and recently described Th17 cells raises new concerns. …”
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    Comprehensive insight into immune regulatory mechanisms and vascular wall determinants of atherogenesis – emerging perspectives of immunomodulation
  8. 3588
    “…The transcription factor Bcl-6 orchestrates the germinal center reaction through its actions in B and T cells, and regulates inflammatory signaling in macrophages. …”
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    Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated through distinct biochemical mechanisms
  9. 3589
    “…Despite extensive structural characterisation of the usher, a number of questions about its mechanism remain, notably its oligomerisation state, and how it orchestrates the ordered assembly of pilus subunits. …”
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    Dissection of Pilus Tip Assembly by the FimD Usher Monomer
  10. 3590
    “…We discuss how PC1 may orchestrate appropriate epithelial responses to renal injury, and how this system may lead to aberrant STAT activation in ADPKD thereby causing inappropriate activation of tissue repair programs that culminate in renal cyst growth and fibrosis.…”
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    Regulation of STATs by polycystin-1 and their role in polycystic kidney disease
  11. 3591
    “…These data introduce Sox17 as a component of the complex signalling network that orchestrates arterial/venous specification.…”
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    Sox17 is indispensable for acquisition and maintenance of arterial identity
  12. 3592
    “…Thus, the discovery of xanthatin, which has ability to simultaneously orchestrate two independent signaling cascades, may have important implications for screening promising drugs in cancer therapies.…”
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    Concerted Suppression of STAT3 and GSK3β Is Involved in Growth Inhibition of Non-Small Cell Lung Cancer by Xanthatin
  13. 3593
    “…Microglia cells are the major orchestrator of the brain inflammatory response. As such, they are traditionally studied in various contexts of trauma, injury, and disease, where they are well-known for regulating a wide range of physiological processes by their release of proinflammatory cytokines, reactive oxygen species, and trophic factors, among other crucial mediators. …”
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    Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis
  14. 3594
    “…In this review we describe the proteins orchestrating mitochondrial translation initiation: bacterial-like general initiation factors mIF2 and mIF3, as well as mitochondria-specific components – mRNA-specific translational activators and mRNA-nonspecific accessory initiation factors. …”
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    Mitochondrial translation initiation machinery: Conservation and diversification()
  15. 3595
    por Rosa, Stefanie, Shaw, Peter
    Publicado 2013
    “…In recent years, it has been shown that this organization is dynamically orchestrated to regulate responses to exogenous stimuli as well as to guide complex cell-type-specific developmental programs. …”
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    Insights into Chromatin Structure and Dynamics in Plants
  16. 3596
    por Visvader, Jane E., Stingl, John
    Publicado 2014
    “…The mammary epithelium is highly responsive to local and systemic signals, which orchestrate morphogenesis of the ductal tree during puberty and pregnancy. …”
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    Mammary stem cells and the differentiation hierarchy: current status and perspectives
  17. 3597
    por DITTMER, JÜRGEN, LEYH, BENJAMIN
    Publicado 2014
    “…These paracrine mechanisms may allow stem cells to orchestrate wound healing and cancer progression. Hence, understanding these stem cell-driven paracrine effects may help to improve tissue regeneration and cancer treatment.…”
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    Paracrine effects of stem cells in wound healing and cancer progression
  18. 3598
    “…MicroRNAs orchestrate the expression of the genome and impact many, if not all, cellular processes. …”
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    The Potential of MicroRNAs in Personalized Medicine against Cancers
  19. 3599
    por Kazantseva, Jekaterina, Palm, Kaia
    Publicado 2014
    “…In the light of our recent findings, induction, control and maintenance of cell differentiation status implies diversification of the transcription initiation apparatus orchestrated by alternative splicing.…”
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    Diversity in TAF Proteomics: Consequences for Cellular Differentiation and Migration
  20. 3600
    por Bigham, Abigail W., Lee, Frank S.
    Publicado 2014
    “…In some populations, genetic signatures have been identified in the hypoxia-inducible factor (HIF) pathway, which orchestrates the transcriptional response to hypoxia. …”
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    Human high-altitude adaptation: forward genetics meets the HIF pathway
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