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1821“…Furthermore, the importance of a crosstalk between MDSCs and natural killer T cells to induce tolerance has been reported. Thus, orchestration between MDSCs, myeloid regulators, T/Bregs and other lymphoid/myeloid regulators can shed light on achieving allogeneic tolerance. …”
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1822Interactions Between Nanoparticles and Dendritic Cells: From the Perspective of Cancer Immunotherapy“…Dendritic cells (DCs) are the primary antigen-presenting cells and play key roles in the orchestration of the innate and adaptive immune system. …”
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1823“…While extensive research is being undertaken to determine the function of the molecular aberrations in DIPG, there are significant gaps in understanding the biology and the influence of the tumour microenvironment on DIPG growth, specifically in regards to the developing pons. The precise orchestration and co-ordination of the development of the brain, the most complex organ in the body, is still not fully understood. …”
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1824por Sato, Keisaku, Kennedy, Lindsey, Liangpunsakul, Suthat, Kusumanchi, Praveen, Yang, Zhihong, Meng, Fanyin, Glaser, Shannon, Francis, Heather, Alpini, Gianfranco“…Liver diseases are perpetuated by the orchestration of hepatocytes and other hepatic non-parenchymal cells. …”
Publicado 2019
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1825“…In this context, cell-free synthetic biology (CFSB) has been developed and recognized as a robust testing and biomanufacturing platform for highly efficient UNAA incorporation. It enables the orchestration of unnatural biological machinery toward an exclusive user-defined objective of unnatural protein synthesis. …”
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1826por Huilgol, Dhananjay, Venkataramani, Prabhadevi, Nandi, Saikat, Bhattacharjee, Sonali“…Development requires the careful orchestration of several biological events in order to create any structure and, eventually, to build an entire organism. …”
Publicado 2019
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1827“…To avoid this situation, cells have developed an arsenal of molecular complexes involving helicases, resolvases, and dissolvases that recognize and eliminate chromosome links. The correct orchestration of these enzymes promotes the timely removal of chromosomal connections ensuring the efficient segregation of the genome during cell division. …”
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1828por Egger, Andjela N., Rajabi‐Estarabadi, Ali, Williams, Natalie M., Resnik, Sydney R., Fox, Joshua D., Wong, Lulu L., Jozic, Ivan“…Caveolae are flask‐shaped invaginations of the cell membrane rich in cholesterol and sphingomyelin, with caveolin proteins acting as their primary structural components that allow compartmentalization and orchestration of various signalling molecules. In this review, we discuss how pleiotropic functions of caveolin‐1 (Cav1) and its intricate roles in numerous cellular functions including lipid trafficking, signalling, cell migration and proliferation, as well as cellular senescence, infection and inflammation, are integral for normal development and functioning of skin and its appendages. …”
Publicado 2020
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1829por Tanaka, Motomu“…This review sheds light on how the structure and function of soft and biological matter in aquatic environments are modulated by the orchestration of various interfacial forces.…”
Publicado 2020
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1830“…Three variants of the architecture have been proposed, which incorporate: individual MEP/MEPM for each slice, shared ones for multiple network slices and Distributed Autonomous Slice Management and Orchestration (DASMO) approach. Each variant is focused on efficient integration of 5G Core and MEC solutions and utilizing additional functionalities of both components, including MEC APIs and 5G Control Plane exposure capabilities. …”
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1831“…Previous work was limited to multi-core parallelism or relied on manual orchestration of the solving process. Our approach uses one master per problem to initialize the solving process and automatically discovers and releases compute nodes through elastic resource usage. …”
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1832“…The mechanism of DA closure is a complex process involving an orchestration of cell–matrix interaction between smooth muscle cells (SMC), endothelial cells, and extracellular matrix (ECM). …”
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1833por Baggiani, Matteo, Dell’Anno, Maria Teresa, Pistello, Mauro, Conti, Luciano, Onorati, Marco“…Building and functioning of the human brain requires the precise orchestration and execution of myriad molecular and cellular processes, across a multitude of cell types and over an extended period of time. …”
Publicado 2020
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1834“…In conclusion, the brain is an endocrine organ through secretion and nuclear transfer of PTMS, and the hypothalamus–brain orchestration of this function is protective in physiology and counteractive against aging-related disorders.…”
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1835“…New findings by Sinturel and colleagues (pp. 329–334) in this issue of Genes & Development now show the requirement of the SCN for temporal orchestration of the periphery in living animals. Surprisingly, this study also found that even in the absence of SCN or extra-SCN clocks, peripheral clocks remain rhythmic, indicating previously controversial circadian oscillator coupling within peripheral tissues.…”
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1836por Graney, Pamela L., Tavakol, Daniel Naveed, Chramiec, Alan, Ronaldson-Bouchard, Kacey, Vunjak-Novakovic, Gordana“…Metastasis is a highly complex and dynamic process that requires orchestration of signaling between the tumor, its local environment, distant tissue sites, and immune system. …”
Publicado 2021
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1837por Capuccini, Marco, Larsson, Anders, Carone, Matteo, Novella, Jon Ander, Sadawi, Noureddin, Gao, Jianliang, Toor, Salman, Spjuth, Ola“…Here we present a microservice-oriented methodology, where scientific applications run in a distributed orchestration platform as software containers, referred to as on-demand, virtual research environments. …”
Publicado 2019
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1838por Caputo, Marina, Pigni, Stella, Agosti, Emanuela, Daffara, Tommaso, Ferrero, Alice, Filigheddu, Nicoletta, Prodam, Flavia“…Indeed, nutrients are crucial modifiers of the GH/IGF-I axis, and these hormones also regulate the complex orchestration of utilization of nutrients in cell and tissues. …”
Publicado 2021
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1839por Garcia, A. Denise R.“…Astrocytes play central roles in a broad array of nervous system functions, including synapse formation and function as well as coordination and orchestration of CNS inflammatory responses in pathological states. …”
Publicado 2021
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1840“…Specificity and accuracy of the autophagic process is maintained via the precision of interaction of autophagy receptors or adaptors and substrates by the intricate, stepwise orchestration of specialized integrating stimuli. Polymorphisms in genes regulating selective autophagy have been linked to aging and age-associated disorders. …”
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