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1941por Huerta, Mario, Casanova, Oriol, Barchino, Roberto, Flores, Jose, Querol, Enrique, Cedano, Juan“…Organisms simplify the orchestration of gene expression by coregulating genes whose products function together in the cell. …”
Publicado 2014
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1942“…Brain development requires precise orchestration of cellular events through the coordinate exchange of information between distally located cells. …”
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1943“…We describe how the particular morphology of these cells is related to their roles in the orchestration of cortical development and their influence on other progenitor types and post-mitotic neurons. …”
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1944“…Dendritic cells (DCs) play a pivotal role in the orchestration of immune responses, and are thus key targets in cancer vaccine design. …”
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1945“…The three-dimensional (3D) structure of the genome is important for orchestration of gene expression and cell differentiation. …”
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1946por Fylaktopoulos, G., Goumas, G., Skolarikis, M., Sotiropoulos, A., Maglogiannis, I.“…The surveyed systems cover the whole spectrum of cloud-based development including integrated programming environments, code repositories, software modeling, composition and documentation tools, and application management and orchestration. In this work we evaluate the existing cloud development ecosystem based on a wide number of characteristics like applicability (e.g. programming and database technologies supported), productivity enhancement (e.g. editor capabilities, debugging tools), support for collaboration (e.g. repository functionality, version control) and post-development application hosting and we compare the surveyed systems. …”
Publicado 2016
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1947“…We confirm that PINK1 mutations causing Parkinson disease interfere with the orchestration of selective fission and mitophagy by PINK1.…”
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1948por Yokouchi, Mariko, Atsugi, Toru, van Logtestijn, Mark, Tanaka, Reiko J, Kajimura, Mayumi, Suematsu, Makoto, Furuse, Mikio, Amagai, Masayuki, Kubo, Akiharu“…We propose a spatiotemporal orchestration model of f-TKD cell turnover, where in the classic context of 'form follows function', cell shape provides a fundamental basis for the barrier homeostasis and physical strength of cornified stratified epithelia. …”
Publicado 2016
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1949por Dyer, Douglas P., Pallas, Kenneth, Ruiz, Laura Medina, Schuette, Fabian, Wilson, Gillian J., Graham, Gerard J.“…Our data therefore reveal novel and previously unanticipated roles for CXCR2 in the orchestration of the inflammatory response.…”
Publicado 2017
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1950“…Understanding these phenomena may even help us to dissect part of the rather complex molecular orchestration happening in our synapses. When exposed unsuccessfully to mating pheromone, i.e. when mating does not happen, budding yeast cells become refractory to the mating signal. …”
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1951“…We design a security service orchestration center in the control plane of SDN, and this center physically decouples from the SDN controller and constructs SDN security services. …”
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1952por Galas, Ludovic, Bénard, Magalie, Lebon, Alexis, Komuro, Yutaro, Schapman, Damien, Vaudry, Hubert, Vaudry, David, Komuro, Hitoshi“…Due to its continuing development after birth, the cerebellum represents a unique model for studying the postnatal orchestration of interneuron migration. The combination of fluorescent labeling and ex/in vivo imaging revealed a cellular highway network within cerebellar cortical layers (the external granular layer, the molecular layer, the Purkinje cell layer, and the internal granular layer). …”
Publicado 2017
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1953“…In this review, we describe what the autophagy–measles virus interplay has taught us about both the biology of the virus and the mechanistic orchestration of autophagy.…”
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1954por Colbey, Candice, Cox, Amanda J., Pyne, David B., Zhang, Ping, Cripps, Allan W., West, Nicholas P.“…Balancing protection of the respiratory tract with normal physiological functioning requires dynamic orchestration between a wide array of immune parameters. …”
Publicado 2018
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1955“…Development of the neocortex requires an orchestration of a series of processes including the appropriate determination, migration and positioning of the neurons, acquisition of layer-specific transcriptional hallmarks, and formation of precise axonal projections and networks. …”
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1956por Álvarez-Mercado, Ana Isabel, Bujaldon, Esther, Gracia-Sancho, Jordi, Peralta, Carmen“…Regeneration involves multiple events and pathways in which several adipokines contribute to their orchestration and drive hepatocytes to proliferate. In addition, ischemia-reperfusion injury is a critical factor in hepatic resection and liver transplantation associated with liver failure or graft dysfunction post-surgery. …”
Publicado 2018
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1957“…In particular, this review describes (i) the mechanisms of viral protein translocation to and from the lipid droplet surface and the orchestration of an interface between replication and assembly complexes, (ii) the importance of the triglyceride mobilization from the lipid droplets for HCV assembly, (iii) the interplay between HCV and the lipoprotein synthesis pathway including the role played by apolipoproteins in virion assembly, and finally (iv) the consequences of these complex virus–host interactions on the virion composition and its biophysical properties. …”
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1958“…There is now ample evidence showing that neutrophils can migrate into different compartments of the lymphoid system where they contribute to the orchestration of the activation and/or suppression of lymphocyte effector functions in homeostasis and during chronic inflammation, such as autoimmune disorders and cancer. …”
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1959“…Several cell populations have been proposed to be involved but it is becoming increasingly evident that group 2 innate lymphoid cells (ILC2s) play a key role in the initiation and orchestration of respiratory allergic inflammation. ILC2s are important mediators of inflammation but also tissue remodeling by secreting large amounts of signature cytokines within a short time period. …”
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1960“…In this article, a Fog architecture based on Kubernetes, an open source container orchestration platform, is proposed to solve this challenge. …”
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