“…Modeling the spatial distribution of pyrethroid resistance and the mechanisms (e.g., kdr mutations) provoking it could enhance current national and departmental vector control programs by classifying areas according to the insecticide resistance status of Ae. aegypti populations and orient strategies such as rotations in endangered areas. …”
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“…The crystal structures were different with [Cu(L(1))(2)(NO(3))(2)] (CuL(1)) crystallizing in the monoclinic space group P2(1)/c, while the 4-methyl derivative CuL(2) was solved and refined in triclinic P [Formula: see text]. The orientation of the Br substituents in the molecular structure (anti (CuL(1)) vs. syn (CuL(2)) conformations) and the geometry around Cu(II) in an overall 4 + 2 distorted coordination was very different with two secondary (axially elongated) Cu–O bonds on each side of the CuN(2)O(2) basal plane in CuL(1) or both on one side in CuL(2). …”
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“…BACKGROUND: Tele-emergency physicians (TEPs) take an increasingly important role in the need-oriented provision of emergency patient care. To improve emergency medicine in rural areas, we set up the project ‘Rural|Rescue’, which uses TEPs to restructure professional rescue services using information and communication technologies (ICTs) in order to reduce the therapy-free interval. …”
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“…In the decoder module, a disease-oriented module is used to extract the most relevant disease representation features. …”
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“…Disorganization is quantified as variations in the orientation of bone components in relation to a target reference point. …”
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“…In parallel, it induced an increase in gap junction connexin-43 plaque size; (ii) NMO-IgG altered the orientation of ciliary basal bodies and functionally impaired cilia motility; (iii) NMO-IgG activated the proliferation of sub-ventricular neural stem cells; (iv) treatment with NMO-IgG up-regulated the expression of pro-inflammatory cytokines and chemokines in the transcriptomic analysis. …”
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“…Leveraging aptamer-tethered VEGF's dynamic affinity interactions with CS that upon hybridization facilitates triggered VEGF release, co-culture studies revealed unique characteristics of aptamer-tethered VEGF to form spatially defined luminal vascular networks covered with filopodia-like structures in vitro (spatial control) and highlights their ability to control network properties including orientation over time using CS as an external trigger (temporal control). …”
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“…Molecular dynamics simulations suggest that the P868L substitution weakens the DNA interaction with the winged-helix domain of BLM and alters the orientation of one lobe of the ATPase domain. Because BLM(core) P868L and G1120R retain helicase function in vitro, it is likely that the increased genome instability is caused by specific impacts of the mutant proteins in vivo. …”
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“…Compared with patients without adverse remodeling, they had lower FA (0.23 ± 0.03 vs 0.27 ± 0.04; P < 0.001), lower E2A (37 ± 6° vs 51 ± 7°; P < 0.001), and, on HA maps, a lower proportion of myocytes with right-handed orientation (RHM) (8% ± 5% vs 17% ± 9%; P < 0.001) in their acutely infarcted myocardium. …”
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“…Subsequently, immature dendritic cells adjacent to dying cancer cells will become mature, further inducing a host-oriented anti-cancer immune response, complicatedly and comprehensively. …”
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“…METHODS: The Aesthetic Perspective Space (APS) is a two-dimensional model that bridges utilitarian-oriented sonification and music. We started with a review of 395 sonification projects, from which a corpus of 32 that target climate change was chosen; a subset of 18 also integrate visualization of the data. …”
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“…Provision of screening services in an organized and strategic people-oriented manner may yield better and sustained outcomes in resource-poor settings than either opportunistic screening or screening offered only as part of routine hospital services.…”
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“…In this study, according to the principle of random matching, the nearest matching method with a matching tolerance of 0.2 and a matching ratio of 1:2 was used for orientation score matching. After the covariant such as age, BMI, and duration of education were balanced, the effects of the duration of endocrine therapy on the overall cognitive function and the functions of each cognitive domain were analyzed. …”
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“…A total of 36 configurations with various loop lengths (8, 10, and 12 mm); loop widths (2.0, 2.5, 3.0, and 3.5 mm); and support structures (open, transverse, and axial) of the VDCD prototypes were designed, fabricated, and tested. Device handling orientations (horizontal and vertical holding angles prior to and during freezing) were also investigated. …”
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“…The aim was to explore the combined use of both information elements for goal-oriented purposes. Fish were trained over time, under operant conditioning, to distinguish a target corner position from its symmetric one (i.e., rotational), thanks to the simultaneous use of surface metrics (long/short, close/far; left-right sense) and a landmark (one surface different in color). …”
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“…Here, we employed G-banding, fluorescence plus Giemsa (FPG), and chromosome orientation fluorescence in situ hybridization (CO-FISH) methodologies to characterize both chromosome-specific frequencies of spontaneously occurring SCE throughout the genome (G-SCE) and telomere-specific SCE (T-SCE). …”
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“…Evidence is presented that OM fortification in the shape mutants restores the ability of MreB cytoskeletal filaments to properly orient the synthesis of new cell wall material by the Rod system. …”
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“…The probes were designed as oriented planar microarrays of 4526 peptide sequences (as overlapping 15-mers) derived from 24 tumor-associated antigens and 209 cancer-related B cell epitopes from 30 viral antigens. …”
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“…Iran's approach both prior to and during the pandemic is strongly aligned with those regional priorities, which are “primary health care-oriented models; enhancing health workforce; promoting equity; enabling environment for research; improving access to countermeasures; and fostering health system resilience.”…”
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“…METHODS: We trained ferrets to localize broadband noise bursts in quiet conditions and measured their initial head orienting responses and approach-to-target behavior. …”
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