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501por Mills, Kimberly I., Kaza, Aditya K., Walsh, Brian K., Bond, Hilary C., Ford, Mackenzie, Wypij, David, Thiagarajan, Ravi R., Almodovar, Melvin C., Quinonez, Luis G., Baird, Christopher W., Emani, Sitaram E., Pigula, Frank A., DiNardo, James A., Kheir, John N.“…DO (2) was closely associated with SVR (r(2)=0.78) but correlated poorly with arterial (SaO(2)) and venous (SvO(2)) oxyhemoglobin concentrations, the Sa‐vO (2) difference, and blood pressure. …”
Publicado 2016
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502por Wu, Jie, Sun, Liang, Li, Haiying, Shen, Haitao, Zhai, Weiwei, Yu, Zhengquan, Chen, Gang“…METHODS: An autologous blood intracerebral hemorrhage model was established in Sprague Dawley rats (weighing 250–300 g), and primary cultured microglia was exposed to oxyhemoglobin to mimic intracerebral hemorrhage in vitro. …”
Publicado 2017
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503por Zhang, Xiangsheng, Wu, Qi, Zhang, Qingrong, Lu, Yue, Liu, Jingpeng, Li, Wei, Lv, Shengyin, Zhou, Mengliang, Zhang, Xin, Hang, Chunhua“…A prechiasmatic cistern injection model was established in rats, and the primary cultured cortical neurons were stimulated with oxyhemoglobin (oxyHb) to induce SAH in vitro. It showed that the NLRP3 inflammasome components, including NLRP3, apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), caspase-1, mature interleukin-1β (IL-1β), and interleukin-18 (IL-18) were upregulated after SAH, and the enhanced NLRP3 after SAH was mainly located in microglia. …”
Publicado 2017
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504por Lu, Yue, Zhang, Xiang-Sheng, Zhang, Zi-Huan, Zhou, Xiao-Ming, Gao, Yong-Yue, Liu, Guang-Jie, Wang, Han, Wu, Ling-Yun, Li, Wei, Hang, Chun-Hua“…Prx2 was added to culture medium with oxyhemoglobin (OxyHb) to mimic SAH in vitro. Neuronal cell viability was assessed by lactate dehydrogenase (LDH) assay, and neuronal apoptosis was determined by TUNEL staining. …”
Publicado 2018
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505por Pervaiz, Farhan, Chavez, Miguel A., Ellington, Laura E., Grigsby, Matthew, Gilman, Robert H., Miele, Catherine H., Figueroa-Quintanilla, Dante, Compen-Chang, Patricia, Marin-Concha, Julio, McCollum, Eric D., Checkley, William“…The ability to predict radiographically confirmed clinical pneumonia was assessed using logistic regression under four additive scenarios: clinical signs and symptoms only, addition of lung auscultation, addition of oxyhemoglobin saturation (Spo(2)), and addition of lung ultrasound. …”
Publicado 2018
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506por Kaynezhad, Pardis, Mitra, Subhabrata, Bale, Gemma, Bauer, Cornelius, Lingam, Ingran, Meehan, Christopher, Avdic-Belltheus, Adnan, Martinello, Kathryn A., Bainbridge, Alan, Robertson, Nicola J., Tachtsidis, Ilias“…We describe the development of a miniaturized broadband near-infrared spectroscopy system (bNIRS), which measures changes in cerebral tissue oxyhemoglobin ([Formula: see text]) and deoxyhemoglobin ([HHb]) plus tissue metabolism via changes in the oxidation state of cytochrome-c-oxidase ([oxCCO]). …”
Publicado 2019
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507por Yang, Le, Yan, Jian, Zhang, Jin-An, Zhou, Xin-Hui, Fang, Chao, Zeng, Er-Ming, Tang, Bin, Duan, Jian, Lu, Guo-Hui, Hong, Tao“…The aim of this study was to investigate the importance of connexin 43 (Cx43) in CVS and determine whether Cx43 alterations are modulated via the protein kinase C (PKC) signaling transduction pathway. METHODS: Oxyhemoglobin (OxyHb)-induced smooth muscle cells of basilar arterial and second-injection model in rat were used as CVS models in vitro and in vivo. …”
Publicado 2019
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508por Duan, Kai, Liu, Bende, Li, Cesheng, Zhang, Huajun, Yu, Ting, Qu, Jieming, Zhou, Min, Chen, Li, Meng, Shengli, Hu, Yong, Peng, Cheng, Yuan, Mingchao, Huang, Jinyan, Wang, Zejun, Yu, Jianhong, Gao, Xiaoxiao, Wang, Dan, Yu, Xiaoqi, Li, Li, Zhang, Jiayou, Wu, Xiao, Li, Bei, Xu, Yanping, Chen, Wei, Peng, Yan, Hu, Yeqin, Lin, Lianzhen, Liu, Xuefei, Huang, Shihe, Zhou, Zhijun, Zhang, Lianghao, Wang, Yue, Zhang, Zhi, Deng, Kun, Xia, Zhiwu, Gong, Qin, Zhang, Wei, Zheng, Xiaobei, Liu, Ying, Yang, Huichuan, Zhou, Dongbo, Yu, Ding, Hou, Jifeng, Shi, Zhengli, Chen, Saijuan, Chen, Zhu, Zhang, Xinxin, Yang, Xiaoming“…The clinical symptoms were significantly improved along with increase of oxyhemoglobin saturation within 3 d. Several parameters tended to improve as compared to pretransfusion, including increased lymphocyte counts (0.65 × 10(9)/L vs. 0.76 × 10(9)/L) and decreased C-reactive protein (55.98 mg/L vs. 18.13 mg/L). …”
Publicado 2020
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509por Peebles, E.D., Elliott, K.E.C., Branton, S.L., Evans, J.D., Leigh, S.A., Kim, E.J., Olanrewaju, H.A., Pharr, G.T., Pavlidis, H.O., Gerard, P.D.“…The R(low)MG challenge significantly increased blood carbon dioxide partial pressure, calcium, sodium, anion gap, osmolality, glucose, and corticosterone levels but significantly decreased blood oxygen partial pressure, oxyhemoglobin concentration, concentration of oxygen dissolved in the blood, chloride, and pH levels. …”
Publicado 2020
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510por Webb, Jeffrey B., Bray, Aaron, Asare, Philip K., Clipp, Rachel B., Mehta, Yatin B., Penupolu, Sudheer, Patel, Aalpen A., Poler, S. Mark“…In addition to lung mechanics or estimation of CO(2) and pH expected for set ventilation parameters (considerations of lung physiology alone), full physiological simulation provides estimates of additional values for oxyhemoglobin saturation, arterial oxygen tension, and other patient parameters. …”
Publicado 2020
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511por Ortiz-Chura, Abimael, Marcoppido, Gisela, Gere, José, Depetris, Gustavo, Stefañuk, Francisco, Trangoni, Marcos D., Cravero, Silvio L., Faverín, Claudia, Cataldi, Angel, Cerón-Cucchi, María E.“…Methemoglobin (MetHb) and deoxyhemoglobin increased according to the NO(3)(-) concentrations in the diet (p<0.05), while an opposite effect was observed for oxyhemoglobin and carboxyhemoglobin (p<0.05). Hematocrit levels decreased (p<0.05), while albumin, alanine aminotransferase, and gamma-glutamyl transpeptidase concentrations were not modified (p>0.05). …”
Publicado 2021
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512por Kim, Jinuk, Kim, Heegoo, Lee, Jungsoo, Lee, Hwang-Jae, Na, Yoonju, Chang, Won Hyuk, Kim, Yun-Hee“…For all participants, functional near-infrared spectroscopy (fNIRS) was applied for measurement of cerebral oxyhemoglobin (oxyHb) and deoxyhemoglobin (deoxyHb) concentration over the non-dominant (right) hemisphere during a serial reaction time task (SRTT) with the non-dominant (left) hand before and after each condition. …”
Publicado 2021
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513por Frangopoulos, Frangiskos, Zannetos, Savvas, Nicolaou, Ivi, Economou, Nicholas-Tiberio, Adamide, Tonia, Georgiou, Andreas, Nikolaidis, Pantelis T., Rosemann, Thomas, Knechtle, Beat, Trakada, Georgia“…The two groups had no differences in OSA severity—as expressed by apnea–hypopnea index (AHI), oxygen desaturation index (ODI), and mean oxyhemoglobin saturation (SaO(2))—and in cardiometabolic comorbidities. …”
Publicado 2021
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514por Morelli, Jacopo, Rossi, Sophie, Fuchs, Boris, Richard, Emmanuelle, Barros, Daniela S. B., Küker, Susanne, Arnemo, Jon M., Evans, Alina L.“…Agreement between the pulse oximeter and the blood gas analyzer was low, with the pulse oximeter underestimating the real values of arterial oxyhemoglobin saturation, particularly at higher readings. …”
Publicado 2021
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515por Zhang, Li, Zhang, Xiaolei, Li, Yi Ming, Xiang, Bo Yun, Han, Teng, Wang, Yan, Wang, Chen“…RESULTS: Compared to the low-risk group, total sleep time (TST), the proportion of N3 (N3%) and mean oxygen saturation (SpO(2)mean) were lower, while the arousal index of non-rapid eye movement (NREM) sleep, apnea index (AI) of NREM sleep, apnea hypopnea index (AHI) of NREM sleep, oxygen desaturation index (ODI) and percentage of total sleep time spent with oxyhemoglobin saturation below 90% (TST90) were higher in the moderate-to-high risk group. …”
Publicado 2021
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516por Robba, Chiara, Cardim, Danilo, Ball, Lorenzo, Battaglini, Denise, Dabrowski, Wojciech, Bassetti, Matteo, Giacobbe, Daniele Roberto, Czosnyka, Marek, Badenes, Rafael, Pelosi, Paolo, Matta, Basil“…The aim of this study was to evaluate the role of the integral components of regional cerebral oxygenation (rSO(2)) measured by NIRS [i.e., arterial-oxyhemoglobin (O(2)Hbi) and venous-deoxyhemoglobin (HHbi)-components], as indirect surrogates of cerebral blood flow (CBF) in a cohort of critically ill patients with coronavirus disease 2019 (COVID-19). …”
Publicado 2021
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517por Zhao, Pengfei, He, Zhaohua, Xi, Qiming, Sun, Hongxian, Luo, Yuzhu, Wang, Jiqing, Liu, Xiu, Zhao, Zhidong, Li, Shaobin“…The haplotype combinations H2H3 and H1H3 were more frequent in the Tibetan sheep population, H2H3 increases O(2) carrying capacity by increasing hematocrit and hemoglobin concentrations; H1H3 makes O(2) dissociate more readily from oxyhemoglobin by decreasing partial pressure of oxygen and oxygen saturation. …”
Publicado 2021
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518por Vale-Lira, Amanda, Turri-Silva, Natália, Verboven, Kenneth, Durigan, João Luiz Quagliotti, de Lima, Alexandra Corrêa G. B., Bottaro, Martim, Chiappa, Gaspar R., Hansen, Dominique, Cipriano, Gerson“…We found phenotype differences among those with Weber C severity, with HFrEF patients reaching lower oxyhemoglobin (O(2)Hb, μM) (−10.9 ± 3.8 vs. −23.7 ± 5.7, p = 0.029) during exercise, while HFpEF reached lower O(2)Hb during the recovery period (−3.0 ± 3.4 vs. 5.9 ± 2.8, p = 0.007). …”
Publicado 2022
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519por Tian, Yang, Liu, Binbing, Li, Yuchen, Zhang, Yongzhi, Shao, Jiang, Wu, Pei, Xu, Chao, Chen, Guangduo, Shi, Huaizhang“…BV2 cells and SH-SY5Y cells were co-cultured and stimulated by oxyhemoglobin to establish an in vitro model of SAH. …”
Publicado 2022
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520“…One major challenge in qBOLD is to separate de-oxyhemoglobin’s contribution to R(2)′ from other sources modulating the voxel signal, for instance, R(2), R(2)′ from non-heme iron (R′(2,nh)), and macroscopic magnetic field variations. …”
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