“…Our findings underscore the pivotal role of environmental factors, including the size of living areas and proximity to main roads, in influencing COPD exacerbations. …”
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“…The cecal microbiota of Er-HL had higher richness estimators (Chao1 and ACE) than those of S-LW and L-LW irrespective of diets (p < 0.01). Breed serves as a pivotal determinant in shaping swine gut microbiota. …”
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“…The detection of pathogens associated with respiratory disease is a pivotal part of the diagnostic workup for respiratory disease. …”
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“…Objectives Preoperative fasting plays a pivotal role in adequately preparing patients for anaesthesia and surgical procedures. …”
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“…CONCLUSION: This study unveils IFN-γGs related molecular subsets in pancreatic cancer for the first time, shedding light on the pivotal role of IFN-γGs in the progression of PC. …”
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“…Moreover, the electrolytes play a pivotal role, essentially dictating the creation of optimal microenvironments that drive reaction selectivity. …”
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“…CONCLUSIONS: In this study, RNA sequencing (RNA-Seq) data at different time points after reperfusion were subjected to a series of bioinformatics methods such as PPI network, WGCNA module, etc., and CLEC5A, a pivotal gene associated with CD4(+) T-cells, was found, which may serve as a new target for diagnosis or treatment.…”
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“…BACKGROUND: N6-methyladenosine (m6A) exerted a pivotal role in colon cancer. Nevertheless, the long non-coding RNAs (lncRNAs) associated with this process have yet to be elucidated. …”
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“…Adaptation to this social behavior is aided by quorum sensing (QS), an intercellular communication system pivotal in the expression of social traits. Regardless of its importance in QS regulation, the loss of function of the master regulator LasR is now considered a conserved adaptation of P. aeruginosa, irrespective of the origin of the strains. …”
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“…Background: In recent years, we have witnessed an evolving landscape in the management of chronic pancreatitis (CP). Endoscopy plays a pivotal role in CP management. Because the management of CP is problematic, we aimed to review and evaluate the role of endoscopy in the management of CP. …”
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“…Furthermore, it played a pivotal role in revitalizing the cecal villi of the broilers. …”
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“…These data indicate that the genetically determined balance between the cytokines acting on different T helper cell subsets may play a pivotal role in transmission of and susceptibility to SARS-CoV-2 infection. …”
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“…Notably, future field studies will play a pivotal role in ensuring the effective implementation of a biological control program. …”
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“…Despite limitations in measurement tools, such as body mass index (BMI) and waist circumference, recognizing sedentary behaviors such as prolonged screen time is pivotal. The rapidly rising prevalence of pediatric obesity has become a major public health concern; therefore, we conducted this study to determine the prevalence and association of screen time usage with being overweight in school-going children (aged 8-15 years). …”
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“…As such, BiBga42A represents one of the pivotal enzymes underpinning the symbiosis between bifidobacteria and breastfed infants. …”
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“…These structural details are pivotal for comprehending the physical properties of 2D noble metals. …”
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“…The core targets were TP53, JUN, AKT1, ESR1, TNF, IL6, CCND1, MAPK1, BCL2, EGFR, IL1B, and PTGS2. They played a pivotal role in modulating multiple signaling pathways, such as Endocrine resistance, MAPK signaling pathway, and PI3K-Akt signaling pathway. …”
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“…AIMS: To gain insight into the mechanisms of FP therapeutic effects, we evaluated interleukin (IL)-13 (a type 2 cytokine that seemingly plays a pivotal role in allergic mechanisms) production by mitogen-stimulated peripheral blood mononuclear cells (MNC) in vitro, treated or not with FP. …”
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“…BACKGROUND: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis and repair, growth arrest, apoptosis, genome stability, angiogenesis, development and differentiation. …”
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“…The results demonstrated that the colon cancer-specific gene network captured the most important genetic interactions in several cellular processes, such as proliferation, apoptosis, differentiation, mitogenesis and immunity, which are known to be pivotal for tumourigenesis. Further analysis of the topological architecture of the network identified three known hub cancer genes [interleukin 8 (IL8) (p ≈ 0), desmin (DES) (p = 2.71 × 10(-6)) and enolase 1 (ENO1) (p = 4.19 × 10(-5))], while two novel hub genes [RNA binding motif protein 9 (RBM9) (p = 1.50 × 10(-4)) and ribosomal protein L30 (RPL30) (p = 1.50 × 10(-4))] may define new central elements in the gene network specific to colon cancer. …”
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