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  1. 31861
  2. 31862
    “…Immune infiltrating cells, especially mast cells, may exert a pivotal role in IS progression. Pharmacological agents targeting signatures, their receptors, or mast cells may shed a novel light on therapeutic targets for IS.…”
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  3. 31863
  4. 31864
    “…A relevant number of accumulated proteins and metabolites, especially in embryos, testifies the pivotal role of energetic supply in the preparation of plant growth. …”
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  5. 31865
  6. 31866
  7. 31867
    “…BACKGROUND: E2F transcription factors (E2Fs), code a family of pivotal transcription factors, have been identified as key regulators in tumor tumorigenesis. …”
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  8. 31868
    “…We previously demonstrated that the elevated expression of manic fringe (MFNG) plays a pivotal role in breast cancer. However, the mechanism through which MFNG is regulated remains obscure. …”
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  9. 31869
  10. 31870
  11. 31871
    “…Importantly, the natural protected areas in Amazonas and San Martin, both in current and in the future conditions, do not cover most of the pivotal habitats for X. loweryi. Furthermore, it was evident that the combination of climate change and anthropogenic activities will lead to further habitat loss for this species. …”
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  12. 31872
    “…RATIONALE: The recent research found that IGF regulator genes played a pivotal role in multiple biological processes, which may be developed for cancer treatment. …”
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  13. 31873
  14. 31874
    “…In plants, the vacuolar proton pyrophosphatase (H(+)-PPase) has a pivotal role in PPi homeostasis. We previously demonstrated that the excess cytosolic PPi in the H(+)-PPase loss-of-function fugu5 mutant inhibits gluconeogenesis from seed storage lipids, arrests cell division in cotyledonary palisade tissue, and triggers a compensated cell enlargement (CCE). …”
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  15. 31875
    “…Importantly, strong correlations were identified among crucial taxa (Aerococcaceae, Staphylococcaceae, Muribaculaceae, Lactobacillaceae, Lachnospiraceae and Eggerthellaceae), pivotal metabolites (tyrosine, methionine, sarcosine and creatine) and the motor function and pathological results of mice. …”
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  16. 31876
    “…ABSTRACT: Entomopathogenic nematodes play a pivotal role as biocontrol agents for different species of insect pests, including the red palm weevil. …”
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  17. 31877
    “…Evidence from preclinical models of neuronal injury and aging support a pivotal role for nerve growth factor (NGF) in neuroprotection, resilience, and cognitive function. …”
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  18. 31878
    “…CONCLUSION: These data suggest that the PPARD rs2016520 and rs3777744 polymorphisms are associated with exenatide monotherapy efficacy, due to the pivotal role of PPARδ in regulating insulin resistance through affecting the expression of GLP-1R. …”
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  19. 31879
  20. 31880
    “…Archaea also display excellent adaptability to extreme environments and play pivotal roles in ecological processes, thus exhibiting valuable biotechnological potential. …”
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