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  1. 32561
    “…Social Life and Routines, included the most common themes described by patients and the difficulties experienced within this category. Themes about the pivotal role of socialization and social support that were lost during the pandemic commonly emerged. …”
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  2. 32562
    por Yu, Fei, Mani, Nandita
    Publicado 2020
    “…Although normal operation and services in many libraries have been greatly disrupted, academic libraries in the United States were reportedly responding to challenges by pivoting to new ways to meet the users’ needs. This observational study was designed to investigate the status, services, and resources disclosed via websites of academic medical/health sciences libraries (MHSLs) in the United States and document how they adapted and continued to provide support to help fight the health crisis and the resulting “infodemic” through various means. …”
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  3. 32563
    “…The etiopathogenesis of pruritus in those disorders sheds light on the link among psychopathological features, psychological stress and the subtle interface between allergic and autoimmune mechanisms, where mast cells play a pivotal role. Allergy has long been recognised as an altered reactivity to exogenous antigens (allergens), defined as an immediate hypersensitivity mediated by immunoglobulin E (IgE). …”
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  4. 32564
    “…In stroke care, the extent of irreversible brain injury, termed infarct core, plays a key role in determining eligibility for acute treatments, such as intravenous thrombolysis and endovascular reperfusion therapies. Many of the pivotal randomized clinical trials testing those therapies used MRI Diffusion-Weighted Imaging (DWI) or CT Perfusion (CTP) to define infarct core. …”
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  5. 32565
    “…The final analysis included 11 articles, consisting of 10 observational studies and a pivotal trial. Cumulative results revealed that the TAo approach had a significantly lower incidence of vascular complications (RR = 2.30; 95% CI = 1.22 to 4.35), and the need for implantation of a permanent pacemaker (RR = 1.82; 95% CI = 1.30 to 2.54) along with a lower amount of contrast (mean difference (MD) = 27.40; 95% CI = 3.73 to 51.08) needed to be used. …”
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  6. 32566
    “…Further analysis of the subtype 2 population demonstrated that GATM (glycine amidinotransferase), as a novel gene associated with PBRM1 mutation, plays a pivotal role in ccRCC by using a cell culture model, revealing tumor, suppressive-like features in reducing proliferation and migration. …”
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  7. 32567
    “…All these results showed that the Mg ion concentration of intraperitoneally-injected extract solutions was a determinant of mouse survival, and a high Mg ion concentration (more than 240 mM) was the pivotal factor contributing to the death of the mice, while changes in pH value showed a negligible effect. …”
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  8. 32568
    “…While post-mortem examinations and isolation of the pathogen are pivotal for a proven diagnosis, serological examinations are the basis of epidemiological and monitoring studies. …”
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  9. 32569
    “…BACKGROUND: Carbohydrate Lewis antigens including sialyl Lewis A (sLeA), sialyl Lewis X (sLeX), Lewis X (LeX), and Lewis Y (LeY) are the commonest cell surface glycoconjugates that play pivotal roles in multiple biological processes, including cell adhesion and cell communication events during embryogenesis. …”
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  10. 32570
    “…Initial indications’ pivotal trials tended to be shorter (AOR per month: 0.96, 95%CI [0.93–0.99], p < 0.05), of lower phase design (AOR per clinical phase: 0.28, 95%CI [0.09–0.85], p < 0.05), and enroll more patients (AOR per 100 patients: 1.19, 95%CI [1.01–1.39], p < 0.05). …”
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  11. 32571
    por Yang, Fan, Zhou, Zheng, Guo, Miao, Zhou, Ziyan
    Publicado 2021
    “…Alpha‐ketoglutarate (Alpha‐KG), a precursor of glutamine, is known as a crucial intermediate of the TCA cycle and plays a pivotal role in multiple metabolic processes. As a precursor of glutamate and glutamine, AKG acts as an antioxidant agent as it directly reacts with hydrogen peroxide with formation of succinate, water, and carbon dioxide; meanwhile, it discharges plenty of ATP by oxidative decarboxylation. …”
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  12. 32572
    “…BACKGROUND: Dyslipidemia is a significant threat to global public health due to its pivotal role as a cardiovascular disease (CVD) risk factor. …”
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  13. 32573
  14. 32574
  15. 32575
    “…Strength symmetry is a RTP criteria when considering return to cutting and pivoting sports. Isokinetic dynamometry testing is often done for ACL reconstruction recovery but there is currently little literature on its use in meniscal repair protocols for RTP. …”
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  16. 32576
    “…However, data from an internet search engine (eg, Google) is less studied, although they can provide pivotal real-time surveillance information. The internet data can be employed to improve forecasting performance and provide early warning, especially during the epidemic. …”
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  17. 32577
    “…Nevertheless, predicting immunotherapy responses in BC is still essential. LncRNAs play pivotal roles in cancer development through diverse oncogenic signal pathways. …”
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  18. 32578
  19. 32579
    “…Pre-pregnancy check-up focused on sub-optimal health and utilising here described phenotypes is pivotal for advanced health policy. PLAIN ENGLISH ABSTRACT: Cardiovascular health is decisive for reproductive function and healthy pregnancy. …”
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  20. 32580
    “…ABSTRACT: Ferroptosis is a new type of programmed cell death that plays a pivotal role in a variety of tumors. Moreover, immunity is closely related to ferroptosis. …”
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