Cancer Therapy Approval Timings, Review Speed, and Publication of Pivotal Registration Trials in the US and Europe, 2010-2019

por Lythgoe, Mark P., Desai, Aakash, Gyawali, Bishal, Savage, Philip, Krell, Jonathan, Warner, Jeremy L., Khaki, Ali Raza
Publicado 2022

Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening

por Khalajzeyqami, Zahra, Grandi, Andrea, Ferrini, Erica, Ravanetti, Francesca, Leo, Ludovica, Mambrini, Martina, Giardino, Luciana, Villetti, Gino, Stellari, Franco Fabio
Publicado 2022

Single strand gap repair: The presynaptic phase plays a pivotal role in modulating lesion tolerance pathways

por Laureti, Luisa, Lee, Lara, Philippin, Gaëlle, Kahi, Michel, Pagès, Vincent
Publicado 2022

A Comparison of Inertial Measurement Unit and Motion Capture Measurements of Tibiofemoral Kinematics during Simulated Pivot Landings

por Baek, So Young, Ajdaroski, Mirel, Shahshahani, Payam Mirshams, Beaulieu, Mélanie L., Esquivel, Amanda O., Ashton-Miller, James A.
Publicado 2022

Pivotal Role of Phytohormones and Their Responsive Genes in Plant Growth and Their Signaling and Transduction Pathway under Salt Stress in Cotton

por Ahmad, Irshad, Zhu, Guanglong, Zhou, Guisheng, Song, Xudong, Hussein Ibrahim, Muhi Eldeen, Ibrahim Salih, Ebtehal Gabralla, Hussain, Shahid, Younas, Muhammad Usama
Publicado 2022

Proteomic Analysis Reveals Salicylic Acid as a Pivotal Signal Molecule in Rice Response to Blast Disease Infection

por Zhou, Haiying, Hwarari, Delight, Zhang, Yunhui, Mo, Xiaosong, Luo, Yuming, Ma, Hongyu
Publicado 2022

Exposure–response analyses for the MET inhibitor tepotinib including patients in the pivotal VISION trial: support for dosage recommendations

por Xiong, Wenyuan, Hietala, Sofia Friberg, Nyberg, Joakim, Papasouliotis, Orestis, Johne, Andreas, Berghoff, Karin, Goteti, Kosalaram, Dong, Jennifer, Girard, Pascal, Venkatakrishnan, Karthik, Strotmann, Rainer
Publicado 2022

Pivoting from systems “thinking” to systems “doing” in health systems—Documenting stakeholder perspectives from Southeast Asia

por Srivastava, Siddharth, Nambiar, Devaki
Publicado 2022

Functional Characterization of Arylalkylamine N-Acetyltransferase, a Pivotal Gene in Antioxidant Melatonin Biosynthesis from Chlamydomonas reinhardtii

por Hwang, Ok-Jin, Back, Kyoungwhan
Publicado 2022

RBFOX2-regulated TEAD1 alternative splicing plays a pivotal role in Hippo-YAP signaling

por Choi, Sunkyung, Lee, Hyo Seong, Cho, Namjoon, Kim, Inyoung, Cheon, Seongmin, Park, Chungoo, Kim, Eun-Mi, Kim, Wantae, Kim, Kee K
Publicado 2022

PB1828: CADENZA: A PIVOTAL STUDY OF PIVEKIMAB SUNIRINE (IMGN632) IN PATIENTS WITH UNTREATED/FRONTLINE BPDCN

por Pemmaraju, N., Martinelli, G., Todisco, E., Tarella, C., Montesinos, P., Lane, A. A., Erba, H. P., Sweet, K. L., Walter, R. B., Deconinck, E., Wang, E. S., Aribi, A., Ulrikson, M. L., Levy, M. Y., Lebon, D., Marconi, G., DeAngelo, D. J., Rizzieri, D., Konopleva, M., Sloss, C. M., Wang, J., Malcolm, K. A., Zweidler-McKay, P. A., Daver, N. G.
Publicado 2022

Dynamic Species Distribution Modeling Reveals the Pivotal Role of Human-Mediated Long-Distance Dispersal in Plant Invasion

por Botella, Christophe, Bonnet, Pierre, Hui, Cang, Joly, Alexis, Richardson, David M.
Publicado 2022

Hexokinase 2 Is a Pivot for Lovastatin-induced Glycolysis-to-Autophagy Reprogramming in Triple-Negative Breast Cancer Cells

por Xue, Lian, Wu, Mi, Li, Ying, Chen, Sisi, Wu, Muyao, Zhu, Jianyu, Ding, Siyu, Zhang, Qiuting, Zheng, Chanjuan, He, Guangchun, Fu, Shujun, Li, Guifei, Deng, Xiyun
Publicado 2022

Clinical radiographic outcomes and survivorship of medial pivot design total knee arthroplasty: a systematic review of the literature

por Alessio-Mazzola, Mattia, Clemente, Antonio, Russo, Antonio, Mertens, Peter, Burastero, Giorgio, Formica, Matteo, Felli, Lamberto
Publicado 2021

IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin

por Lecron, Jean-Claude, Charreau, Sandrine, Jégou, Jean-François, Salhi, Nadjet, Petit-Paris, Isabelle, Guignouard, Emmanuel, Burucoa, Christophe, Favot-Laforge, Laure, Bodet, Charles, Barra, Anne, Huguier, Vincent, Mcheik, Jiad, Dumoutier, Laure, Garnier, Julien, Bernard, François-Xavier, Ryffel, Bernhard, Morel, Franck
Publicado 2022

Current Activities Centered on Healthy Living and Recommendations for the Future: A Position Statement from the HL-PIVOT Network

por Arena, Ross, Myers, Jonathan, Kaminsky, Leonard A., Williams, Mark, Sabbahi, Ahmad, Popovic, Dejana, Axtell, Robert, Faghy, Mark A., Hills, Andrew P., Olivares Olivares, Silvia Lizett, Lopez, Mildred, Pronk, Nicolaas P., Laddu, Deepika, Babu, Abraham Samuel, Josephson, Richard, Whitsel, Laurie P., Severin, Rich, Christle, Jeffrey W., Dourado, Victor Zuniga, Niebauer, Josef, Savage, Patrick, Austford, Leslie D., Lavie, Carl J
Publicado 2021

An innovative approach for the evaluation of prolonged disorders of consciousness using NF-L and GFAP biomarkers: a pivotal study

por Coppola, L., Mirabelli, P., Baldi, D., Smaldone, G., Estraneo, A., Soddu, A., Grimaldi, A. M., Mele, G., Salvatore, Marco, Cavaliere, Carlo
Publicado 2022

Genome-Scale Investigation of GARP Family Genes Reveals Their Pivotal Roles in Nutrient Stress Resistance in Allotetraploid Rapeseed

por Hua, Ying-Peng, Wu, Peng-Jia, Zhang, Tian-Yu, Song, Hai-Li, Zhang, Yi-Fan, Chen, Jun-Fan, Yue, Cai-Peng, Huang, Jin-Yong, Sun, Tao, Zhou, Ting
Publicado 2022

Cell-based analysis reveals that sex-determining gene signals in Ostrinia are pivotally changed by male-killing Wolbachia

por Herran, Benjamin, Sugimoto, Takafumi N, Watanabe, Kazuyo, Imanishi, Shigeo, Tsuchida, Tsutomu, Matsuo, Takashi, Ishikawa, Yukio, Kageyama, Daisuke
Publicado 2022

Prior Bexarotene or Phototherapy Does Not Affect Response to Chlormethine Gel: Post Hoc Analysis of a Pivotal Trial

por ASSAF, Chalid, QUERFELD, Christiane, SCANDURRA, Marta, TURINI, Marco, SCARISBRICK, Julia J.
Publicado 2023