Dual immunological and proliferative regulation of immune checkpoint FGL1 in lung adenocarcinoma: The pivotal role of the YY1–FGL1–MYH9 axis

por Tang, Xi-Yang, Xiong, Yan-Lu, Zhao, Ya-Bo, Yang, Jie, Shi, An-Ping, Zheng, Kai-Fu, Liu, Yu-Jian, Shu, Chen, Jiang, Tao, Ma, Nan, Zhao, Jin-Bo
Publicado 2022

Immune-associated pivotal biomarkers identification and competing endogenous RNA network construction in post-operative atrial fibrillation by comprehensive bioinformatics and machine learning strategies

por Zhou, Yufei, Wu, Qianyun, Ni, Gehui, Hong, Yulu, Xiao, Shengjue, Liu, Chunjiang, Yu, Zongliang
Publicado 2022

Medial Pivot Designs Versus Conventional Bearing Types in Primary Total Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

por Hoskins, Wayne, Smith, Guy, Spelman, Tim, Vince, Kelly G.
Publicado 2022

Steeper lateral posterior tibial slope and greater lateral-medial slope asymmetry correlate with greater preoperative pivot-shift in anterior cruciate ligament injury

por Kataoka, Kiminari, Nagai, Kanto, Hoshino, Yuichi, Shimabukuro, Masashi, Nishida, Kyohei, Kanzaki, Noriyuki, Matsushita, Takehiko, Kuroda, Ryosuke
Publicado 2022

Nebivolol: an effective option against long-lasting dyspnoea following COVID-19 pneumonia - a pivotal double-blind, cross-over controlled study

por Dal Negro, Roberto W., Turco, Paola, Povero, Massimiliano
Publicado 2022

Ultra high vacuum tests and experience of a long life, heavy duty, oscillating rod end pivot for the movable ferrite shutters of the CERN antiproton accumulator

por Poncet, Alain
Publicado 1980

Larger Medial Contact Area and More Anterior Contact Position in Medial-Pivot than Posterior-Stabilized Total Knee Arthroplasty during In-Vivo Lunge Activity

por Zou, Diyang, Tan, Jiaqi, Zheng, Nan, Ling, Zhi, Yu, Wanxin, Liow, Ming Han Lincoln, Chen, Yunsu, Tsai, Tsung-Yuan
Publicado 2023

Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease

por Smart, Luke R., Segbefia, Catherine I., Latham, Teresa S., Stuber, Susan E., Amissah-Arthur, Kwesi N., Dzefi-Tettey, Klenam, Lane, Adam C., Dei-Adomakoh, Yvonne A., Ware, Russell E.
Publicado 2023

The secreted purple acid phosphatase isozymes AtPAP12 and AtPAP26 play a pivotal role in extracellular phosphate-scavenging by Arabidopsis thaliana

por Robinson, Whitney D., Park, Joonho, Tran, Hue T., Del Vecchio, Hernan A., Ying, Sheng, Zins, Jacqui L., Patel, Ketan, McKnight, Thomas D., Plaxton, William C.
Publicado 2012

Cause of death in MS: long-term follow-up of a randomised cohort, 21 years after the start of the pivotal IFNβ-1b study

por Goodin, Douglas S, Ebers, George C, Cutter, Gary, Cook, Stuart D, O'Donnell, Timothy, Reder, Anthony T, Kremenchutzky, Marcelo, Oger, Joel, Rametta, Mark, Beckmann, Karola, Knappertz, Volker
Publicado 2012

Pivotal Role of Timely Basal Insulin Replacement After Metformin Failure in Sustaining Long-Term Blood Glucose Control at a Target in Type 2 Diabetes

por Bolli, Geremia B., Lucidi, Paola, Porcellati, Francesca, Fanelli, Carmine G.
Publicado 2011

A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation

por Wang, Jian-Da, Cao, Yu-Lan, Li, Qian, Yang, Ya-Ping, Jin, Mengmeng, Chen, Dong, Wang, Fen, Wang, Guang-Hui, Qin, Zheng-Hong, Hu, Li-Fang, Liu, Chun-Feng
Publicado 2015

tPA-MMP-9 Axis Plays a Pivotal Role in Mobilization of Endothelial Progenitor Cells from Bone Marrow to Circulation and Ischemic Region for Angiogenesis

por Leu, Steve, Day, Yuan-Ji, Sun, Cheuk-Kwan, Yip, Hon-Kan
Publicado 2016

Comparison of treatment effect sizes from pivotal and postapproval trials of novel therapeutics approved by the FDA based on surrogate markers of disease: a meta-epidemiological study

por Wallach, Joshua D., Ciani, Oriana, Pease, Alison M., Gonsalves, Gregg S., Krumholz, Harlan M., Taylor, Rod S., Ross, Joseph S.
Publicado 2018

Canakinumab in patients with systemic juvenile idiopathic arthritis and active systemic features: results from the 5-year long-term extension of the phase III pivotal trials

por Ruperto, Nicolino, Brunner, Hermine I, Quartier, Pierre, Constantin, Tamàs, Wulffraat, Nico M, Horneff, Gerd, Kasapcopur, Ozgur, Schneider, Rayfel, Anton, Jordi, Barash, Judith, Berner, Reinhard, Corona, Fabrizia, Cuttica, Ruben, Fouillet-desjonqueres, Marine, Fischbach, Michel, Foster, Helen E, Foell, Dirk, Radominski, Sebastião C, Ramanan, Athimalaipet V, Trauzeddel, Ralf, Unsal, Erbil, Levy, Jérémy, Vritzali, Eleni, Martini, Alberto, Lovell, Daniel J
Publicado 2018

Characteristics of Single Pivotal Trials Supporting Regulatory Approvals of Novel Non‐orphan, Non‐oncology Drugs in the European Union and United States from 2012−2016

por Morant, Anne Vinther, Jagalski, Vivien, Vestergaard, Henrik Tang
Publicado 2019

RrMYB5‐ and RrMYB10‐regulated flavonoid biosynthesis plays a pivotal role in feedback loop responding to wounding and oxidation in Rosa rugosa

por Shen, Yuxiao, Sun, Tingting, Pan, Qi, Anupol, Nachaisin, Chen, Hai, Shi, Jiewei, Liu, Fang, Deqiang, Duanmu, Wang, Changquan, Zhao, Jian, Yang, Shuhua, Wang, Caiyun, Liu, Jihong, Bao, Manzhu, Ning, Guogui
Publicado 2019

3. Phase 3 Pivotal Evaluation of 20-valent Pneumococcal Conjugate Vaccine (PCV20) Safety, Tolerability, and Immunologic Noninferiority in Participants 18 Years and Older

por Essink, Brandon, Sabharwal, Charu, Xu, Xia, Sundaraiyer, Vani, Peng, Yahong, Moyer, Lisa, Pride, Michael W, Scully, Ingrid L, Jansen, Kathrin U, Gruber, William C, Scott, Daniel, Watson, Wendy
Publicado 2020

Polyadenylated Telomeric Noncoding RNA Functions as a Pivotal Therapeutic Target of Anti-Ageing to Stabilize Telomere Length of Chromosomes Via Collaborating With Zscan4c

por Xu, Xiaojuan, Chen, Zhengju, Wu, Wei, Tian, Xiaohe
Publicado 2022

miR-199a-5p Plays a Pivotal Role on Wound Healing via Suppressing VEGFA and ROCK1 in Diabetic Ulcer Foot

por Wang, Hongshu, Wang, Xianyi, Liu, Xiaomin, Zhou, Jinbao, Yang, Qianqian, Chai, Binshu, Chai, Yimin, Ma, Zhongliang, Lu, Shengdi
Publicado 2022