Association between osteocalcin, a pivotal marker of bone metabolism, and secretory function of islet beta cells and alpha cells in Chinese patients with type 2 diabetes mellitus: an observational study

por Lei, Haiyan, Liu, Jun, Wang, Wei, Yang, Xinyi, Feng, Zhouqin, Zang, Pu, Lu, Bin, Shao, Jiaqing
Publicado 2022

Clinicians Are Not Able to Infer Parental Intentions to Vaccinate Infants with a Seasonal Influenza Vaccine, and Perhaps They Should Not Try: Findings from the Pediatric Influenza Vaccination Optimization Trial (PIVOT)–IV

por Fisher, William A., Gilca, Vladimir, Murti, Michelle, Orth, Alison, Garfield, Hartley, Roumeliotis, Paul, Rampakakis, Emmanouil, Brown, Vivien, Yaremko, John, Van Buynder, Paul, Boikos, Constantina, Mansi, James A.
Publicado 2022

P1078: MOSUNETUZUMAB DEMONSTRATES DURABLE RESPONSES IN PATIENTS WITH RELAPSED AND/OR REFRACTORY FOLLICULAR LYMPHOMA WHO HAVE RECEIVED ≥2 PRIOR THERAPIES: UPDATED ANALYSIS OF A PIVOTAL PHASE II STUDY

por Sehn, Laurie H., Bartlett, Nancy L., Matasar, Matthew, Schuster, Stephen J., Assouline, Sarit, Kuruvilla, John, Shadman, Mazyar, Cheah, Chan, Fay, Keith, Ku, Matthew, Nastoupil, Loretta J., Wei, Michael, Yin, Shen, To, Iris, Hu, Nan, Min, Juliana, Penuel, Elicia, Belousov, Anton, Coimbra, Alexandre, Jemaa, Skander, Bender, Brendan, Turner, David, Elizabeth Budde, L.
Publicado 2023

P1132: LONG-TERM RESPONSES WITH LONCASTUXIMAB TESIRINE: UPDATED RESULTS FROM LOTIS-2, THE PIVOTAL PHASE 2 STUDY IN PATIENTS WITH RELAPSED/REFRACTORY DIFFUSE LARGE B-CELL LYMPHOMA

por Caimi, Paolo F, Ai, Weiyun Z, Pablo Alderuccio, Juan, Ardeshna, Kirit M, Hamadani, Mehdi, Hess, Brian, Kahl, Brad S, Radford, John, Solh, Melhem, Stathis, Anastasios, Luigi Zinzani, Pier, Wang, Ying, Qin, Yajuan, Wang, Luqiang, Xu, Cindy, Carlo-Stella, Carmelo
Publicado 2023

Response to Comment on: Gorboulev et al. Na(+)-d-glucose Cotransporter SGLT1 Is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion....

por Koepsell, Hermann, Gorboulev, Valentin
Publicado 2012

Longer‐term follow‐up and outcome by tumour cell proliferation rate (Ki‐67) in patients with relapsed/refractory mantle cell lymphoma treated with lenalidomide on MCL‐001(EMERGE) pivotal trial

por Goy, Andre, Kalayoglu Besisik, Sevgi, Drach, Johannes, Ramchandren, Radhakrishnan, Robertson, Michael J., Avivi, Irit, Rowe, Jacob M., Herbrecht, Raoul, Van Hoof, Achiel, Zhang, Lei, Cicero, Sherri, Fu, Tommy, Witzig, Thomas
Publicado 2015

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells

por Dakir, El-Habib, Mollinedo, Faustino
Publicado 2019

Reg3α and Reg3β Expressions Followed by JAK2/STAT3 Activation Play a Pivotal Role in the Acceleration of Liver Hypertrophy in a Rat ALPPS Model

por Otsuka, Naohiko, Yoshioka, Masato, Abe, Yuki, Nakagawa, Yasuhiko, Uchinami, Hiroshi, Yamamoto, Yuzo
Publicado 2020

The risk of respiratory tract infections in patients with psoriasis treated with interleukin 23 pathway–inhibiting biologics: A meta-estimate of pivotal trials relevant to decision making during the COVID-19 pandemic

por Syed, Maha N., Shin, Daniel B., Wan, Marilyn T., Winthrop, Kevin L., Gelfand, Joel M.
Publicado 2020

Comparison of Direct Oral Anticoagulant Use for the Treatment of Non-Valvular Atrial Fibrillation in Pivotal Clinical Trials vs. the Real-World Setting: A Population-Based Study from Southern Italy

por Ingrasciotta, Ylenia, Fontana, Andrea, Mancuso, Anna, Ientile, Valentina, Sultana, Janet, Uomo, Ilaria, Pastorello, Maurizio, Calabrò, Paolo, Andò, Giuseppe, Trifirò, Gianluca
Publicado 2021

The Adjuvanted Recombinant Zoster Vaccine Confers Long-Term Protection Against Herpes Zoster: Interim Results of an Extension Study of the Pivotal Phase 3 Clinical Trials ZOE-50 and ZOE-70

por Boutry, Céline, Hastie, Andrew, Diez-Domingo, Javier, Tinoco, Juan Carlos, Yu, Chong-Jen, Andrews, Charles, Beytout, Jean, Caso, Covadonga, Cheng, Huey-Shinn, Cheong, Hee Jin, Choo, Eun Ju, Curiac, Dan, Di Paolo, Emmanuel, Dionne, Marc, Eckermann, Tamara, Esen, Meral, Ferguson, Murdo, Ghesquiere, Wayne, Hwang, Shinn-Jang, Avelino-Silva, Thiago Junqueira, Kosina, Pavel, Liu, Chiu-Shong, Markkula, Jukka, Moeckesch, Beate, Murta de Oliveira, Cláudia, Park, Dae Won, Pauksens, Karlis, Pirrotta, Paola, Plassmann, Georg, Pretswell, Carol, Rombo, Lars, Salaun, Bruno, Sanmartin Berglund, Johan, Schenkenberger, Isabelle, Schwarz, Tino, Shi, Meng, Ukkonen, Benita, Zahaf, Toufik, Zerbini, Cristiano, Schuind, Anne, Cunningham, Anthony L
Publicado 2021

Evaluation of double-high insert mid-term outcomes in cruciate-retaining medial-pivotal total knee arthroplasty – a propensity score-matched analysis with averaged 8-year follow-up

por Wang, Wenzhe, Xiang, Shuai, Wang, Yingzhen, Lv, Chengyu, Wang, Changyao, Zhang, Haining
Publicado 2022

CLRM-10 METIS (EF-25): A PIVOTAL, RANDOMIZED CONTROLLED STUDY OF TUMOR TREATING FIELDS IN PATIENTS WITH 1–10 BRAIN METASTASES FROM NON-SMALL CELL LUNG CANCER

por Mehta, Minesh, Brown, Paul, Gondi, Vinai, Ahluwalia, Manmeet
Publicado 2022

Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus

por Zhang, Jie, Li, Pengwei, Lu, Riye, Ouyang, Songying, Chang, Ming Xian
Publicado 2022

Parental Attitudes and Perceptions of Support after Brief Clinician Intervention Predict Intentions to Accept the Adjuvanted Seasonal Influenza Vaccination: Findings from the Pediatric Influenza Vaccination Optimization Trial (PIVOT)–I

por Fisher, William A., Gilca, Vladimir, Murti, Michelle, Orth, Alison, Garfield, Hartley, Roumeliotis, Paul, Rampakakis, Emmanouil, Brown, Vivien, Yaremko, John, Van Buynder, Paul, Boikos, Constantina, Mansi, James A.
Publicado 2022

Subgroup analysis of patients with HER2-negative metastatic breast cancer in the second-line setting from a phase 3, open-label, randomized study of eribulin mesilate versus capeci...

por Pivot, Xavier, Im, Seock Ah, Guo, Matthew, Marmé, Frederik
Publicado 2018

Adjuvant Trastuzumab Is Required in Human Epidermal Growth Factor Receptor 2-Positive Node-Negative Breast Cancer Patients Regardless of Tumour Size

por Bender, Laura, Kurtz, Jean-Emmanuel, Petit, Thierry, Pivot, Xavier
Publicado 2020

A Randomized, Open-Label, Multiple-Dose, Parallel-Arm, Pivotal Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Aripiprazole 2-Month Long-Acting Injectable in Adults With Schizophrenia or Bipolar I Disorder

por Harlin, Matthew, Yildirim, Murat, Such, Pedro, Madera-McDonough, Jessica, Jan, Michael, Jin, Na, Watkin, Suzanne, Larsen, Frank
Publicado 2023

P1129: GLOFITAMAB MONOTHERAPY IN PATIENTS WITH RELAPSED/REFRACTORY (R/R) LARGE B-CELL LYMPHOMA (LBCL): EXTENDED FOLLOW-UP AND LANDMARK ANALYSES FROM A PIVOTAL PHASE II STUDY

por Hutchings, Martin, Carlo-Stella, Carmelo, Morschhauser, Franck, Dickinson, Michael, Bachy, Emmanuel, Cartron, Guillaume, Khan, Cyrus, Tani, Monica, Martinez-Lopez, Joaquín, Bartlett, Nancy L., Salar, Antonio, Brody, Joshua, Leppa, Sirpa, Baumlin, Pauline, Lundberg, Linda, Relf, James, Xie, Yuying, Bottos, Alessia, Humphrey, Kathryn, Falchi, Lorenzo
Publicado 2023

The FOsmetpantotenate Replacement Therapy (FORT) randomized, double-blind, Placebo-controlled pivotal trial: Study design and development methodology of a novel primary efficacy outcome in patients with pantothenate kinase-associated neurodegeneration

por Klopstock, Thomas, Escolar, Maria L, Marshall, Randall D, Perez-Dueñas, Belen, Tuller, Sarah, Videnovic, Aleksandar, Greblikas, Feriandas
Publicado 2019