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  1. 1461
    “…For immunogenicity enhancement, different specific sequences like linkers, PADRE sequences and molecular adjuvants were added. …”
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    Multi-epitope chimeric vaccine designing and novel drug targets prioritization against multi-drug resistant Staphylococcus pseudintermedius
  2. 1462
    “…The vaccine is based on the rational design of an immunogen containing two defined B-cell epitopes from the spike glycoprotein of SARS-CoV-2 and the universal T-helper epitope PADRE. The epitopes were conjugated to short DNA probes and combined with a complementary scaffold strand, resulting in sequence-specific self-assembly. …”
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    Modular nanoarray vaccine for SARS-CoV-2
  3. 1463
    “…We then analyzed the epitopes of these proteins and selected 16 helper T lymphocyte epitopes with interferon-γ inducing activity, 15 cytotoxic T lymphocyte epitopes, and 10 linear B-cell epitopes, and conjugated them with adjuvant and Pan HLA DR-binding epitope (PADRE) using appropriate linkers. Moreover, we predicted the tertiary structure of this vaccine, its potential interaction with Toll-Like Receptor-4 (TLR4), and the immune response it might elicit. …”
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    In silico design of a promiscuous chimeric multi-epitope vaccine against Mycobacterium tuberculosis
  4. 1464
    Tabla de Contenidos: “…/ Leonardo Azparren Giménez -- Una breve visita por las tablas libertarias / Carlos Fos -- Instancias queer en "Dos viejos pánicos" de Virgilio Piñera / David William Foster -- Del ayuno o la integridad de la razón en el teatro de Gambaro : acerca de "Del sol naciente" / María Florencia Heredia -- La "Orestéia-O canto do bode" del Folias d' Arte de S{tilde}ao Paulo : la venganza como acto de justicia y el imperio de los nuevos dioses de Olimpo / Mario Rojas -- Gilles Deleuze y el teatro : una relación múltiple / Cristina Piña -- Para los inicios de Alberto Vacarezza : notas sobre el melodrama rural inédito "La noche del forastero" (1904) / Jorge Dubatti -- Recorridos de lo popular en el teatro de Córdoba / Graciela Frega -- Semana Santa en Tandil : patrimonio cultural y teatro religioso / Liliana Iriondo -- Ocupación teatral de la ciudad : creando comunidades fugaces / André Carreira -- "Cremona" (1932), el padre espectral / Patricia Fischer -- El metateatro de Carlos Matorras Cornejo : una escritura "bajo la arena" / Graciela Balestrino y Marcela Sosa -- Teatralidad, traducción y polisistema en la escena contemporánea del Río de la Plata / Roger Mirza -- Claudio Tolcachir : transgresión y refuncionalización del modelo estético realista / Silvina Díaz y Adriana Libonati -- Aproximación a la presencia del teatro argetino en Barcelona / Enric Ciurans -- Biografía y testimonio en la historia teatral : el caso de Florencio Sánchez / Laura Cilento -- Vagabundeo, patetismo cómico, melancolía y revolución en Manuel Medel / Martín Rodríguez -- La memoria de un pasado perdido y la construcción de una nueva identidad : la comedia 1900-1910 / Marina Sikora -- "A la noche íbamos al Babilonia y al Parakultural" : un recuerdo porteño de Osvaldo Pellettieri / Marco De Marinis.…”
    Libro
    Pensar la escena : homenaje a Osvaldo Pellettieri /
  5. 1465
    por Mondragón, Rafael
    Publicado 2022
    “…El texto combina el análisis de planteamientos con la experiencia del autor como padre de una niña recién nacida y enmarca sus reflexiones en el marco de lo que, con Leonardo Boff, podría llamarse “filosofías del cuidado”.Some approaches to the philosophies of care and to fantasy’s powerAbstractIn the present text, the author draws from thinkers such as Federico García Lorca, Janusz Korczak, Ernst Bloch and C. …”
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    Acerca de las filosofías del cuidado y la potencia de la fantasía
  6. 1466
    “…The top lead B and T-cells overlapped epitopes were utilized to generate a chimeric vaccine construct combined with immune-modulating adjuvants, linkers, and PADRE sequences. The top ranked prioritized vaccine construct (V7) showed stable molecular interaction with human immune cell receptors as inferred during the molecular docking and MD simulation analyses. …”
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    Computer-aided genomic data analysis of drug-resistant Neisseria gonorrhoeae for the Identification of alternative therapeutic targets
  7. 1467
    “…The selected epitopes were linked with Salmonella enterica flagellin FliC adjuvants, along with the PADRE sequence, by GGS linkers to construct a vaccine candidate with 272 nucleotides. …”
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    Immunoinformatics for Novel Multi-Epitope Vaccine Development in Canine Parvovirus Infections
  8. 1468
    “…After removing the one toxin (PADRE) from the original vaccine design, it was projected that the new vaccine would not be similar to the human host and would instead be antigenic, immunogenic, non-allergenic, and non-toxic. …”
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    Immunoinformatic Execution and Design of an Anti-Epstein–Barr Virus Vaccine with Multiple Epitopes Triggering Innate and Adaptive Immune Responses
  9. 1469
    “…METHODS: C57BL/6 mice bearing B16-F10 melanoma tumors were vaccinated subcutaneously 6 days post tumor implantation with a mixture of synthetic peptides (modified p53: 232–240, TRP-2: 181–188 and PADRE) and CpG. Tumor growth was monitored and antigen-specific splenocyte responses were assayed by ELISPOT. …”
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    Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax(®)
  10. 1470
    “…We used satellite telemetry and switching state-space modeling (SSM) to identify distinct foraging areas used by Kemp's ridley turtles (Lepidochelys kempii) tagged after nesting during 1998–2011 at Padre Island National Seashore, Texas, USA (PAIS; N = 22), and Rancho Nuevo, Tamaulipas, Mexico (RN; N = 9). …”
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    Foraging area fidelity for Kemp's ridleys in the Gulf of Mexico
  11. 1471
    “…We report on a vaccine strategy that utilises a lipid core peptide (LCP) delivery system with self-adjuvanting properties in conjunction with either the antigenic site Ø or II (B cell epitopes) along with PADRE as a T helper cell epitope. These LCP constructs adopted the desired helical conformation in solution and were recognised by their cognate antibodies D25 and Motavizumab, specific for site Ø and II on RSV F protein, respectively. …”
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    Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein
  12. 1472
    “…For these reasons, we estimated sex ratios and physical condition of hatchling hawksbills under natural and manipulated conditions and generated and analyzed thermal profiles of hawksbill nest environments within highly threatened mangrove ecosystems at Bahía de Jiquilisco, El Salvador, and Estero Padre Ramos, Nicaragua. Hawksbill clutches protected in situ at both sites incubated at higher temperatures, yielded lower hatching success, produced a higher percentage of female hatchlings, and produced less fit offspring than clutches relocated to hatcheries. …”
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    Potential limitations of behavioral plasticity and the role of egg relocation in climate change mitigation for a thermally sensitive endangered species
  13. 1473
    “…Three subunit vaccines were constructed by the combination of highly antigenic epitopes along with suitable adjuvant, PADRE sequence and linkers. The designed vaccine constructs (V1, V2, V3) were analyzed by their physiochemical properties and molecular docking with MHC molecules- results suggested that the V1 is superior. …”
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    Comprehensive genome based analysis of Vibrio parahaemolyticus for identifying novel drug and vaccine molecules: Subtractive proteomics and vaccinomics approach
  14. 1474
    “…We evaluated the most antigenic epitopes that bind to HLA class 1 subtypes, along with HLA class 2, as well as B cell epitopes. Beta-defensin 3 and PADRE sequence were used as adjuvants in the structure of the vaccine. …”
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    A reverse vaccinology and immunoinformatics approach for designing a multiepitope vaccine against SARS-CoV-2
  15. 1475
    “…Following that, a vaccine construct was designed based on CTL, HTL, and BCL epitopes of the selected protein candidates and to finalize the vaccine construct, several amino acid linkers, β-defensin adjuvant, and PADRE peptides were incorporated. The generated potential vaccine was assessed computationally for several properties such as antigenicity, allergenicity, stability, and other structural features where the outcomes of these assessments nominated this potential vaccine to be validated for its binding affinity with two molecular targets TLR-8 and TLR-4. …”
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    Mining of Marburg Virus Proteome for Designing an Epitope-Based Vaccine
  16. 1476
    “…Those four proteins were linked to form a multitope vaccine, that was formulated with a suitable adjuvant, and PADRE peptides to finalize the multitope vaccine construct. …”
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    Integration of immunoinformatics and cheminformatics to design and evaluate a multitope vaccine against Klebsiella pneumoniae and Pseudomonas aeruginosa coinfection
  17. 1477
    por Rojo, Vicente, 1932-2020
    Publicado 2020
    Libro
    Ipanema : Vicente Rojo : 80 años después : cuaderno de viaje de Francisco Rojo Lluch en el vapor Ipanema : Burdeos-Veracruz, junio-julio de 1939 /
  18. 1478
    “…La Ley Agraria de 1917 configuró una familia tradicional fuertemente jerarquizada y sometida al control de las instituciones agrarias y del Estado. En esta familia el padre controlaba la relación con sus hijos. La Reforma de 1992 y la nueva Ley Agraria permiten modificar la propiedad de la tierra y su sistema de gestión y transferencia, con lo que se trastocó el sistema de organización y de sucesión de las familias. …”
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    Las implicaciones intrafamiliares, intergeneracionales y migratorias de la política agraria en México. El caso del sur del estado de Veracruz, México
  19. 1479
    “…We selected twelve common antigenic B cell and T cell epitopes (CTL and HTL) containing the nine RBD mutations and joined them with the adjuvants, PADRE sequence, and suitable linkers. The constructs' binding affinity was confirmed through docking with TLR4/MD2 complex and showed significant binding free energy (−96.67 kcal mol(−1)) with positive binding affinity. …”
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    A novel mutation-proof, next-generation vaccine to fight against upcoming SARS-CoV-2 variants and subvariants, designed through AI enabled approaches and tools, along with the machine learning based immune simulation: A vaccine breakthrough
  20. 1480
    “…These included something called human β-defensins 3 (hBD-3) that we found in a database, and another part that helps the immune system called PADRE. We attached these extra parts to the beginning of the vaccine. …”
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    Design of a multi-epitope vaccine against brucellosis fused to IgG-fc by an immunoinformatics approach
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