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2001por Sugano, Hiroshi, Shirai, Yoshihiro, Sato, Shun, Hamatani, Shigeharu, Hamura, Ryoga, Taniai, Tomohiko, Horiuchi, Takashi, Gocho, Takeshi, Eto, Ken, Ikegami, Toru“…BACKGROUND: Pancreatic cancer is one of the most aggressive digestive cancers. …”
Publicado 2021
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2002“…Pancreatic cancer is a challenging malignancy with limited treatment options and poor life expectancy. …”
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2003por Guo, Shiwei, Shi, Xiaohan, Gao, Suizhi, Hou, Qunxing, Jiang, Lisha, Li, Bo, Shen, Jing, Wang, Huan, Shen, Shuo, Zhang, GuoXiao, Pan, Yaqi, Liu, Wuchao, Xu, Xiongfei, Zheng, Kailian, Shao, Zhuo, Jing, Wei, Lin, Ling, Li, Gang, Jin, Gang“…BACKGROUND: Pancreatic cancer is a life-threatening malignant disease with significant diversity among geographic regions and races leading to distinct carcinogenesis and prognosis. …”
Publicado 2021
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2004por Kremer, Daniel M., Nelson, Barbara S., Lin, Lin, Yarosz, Emily L., Halbrook, Christopher J., Kerk, Samuel A., Sajjakulnukit, Peter, Myers, Amy, Thurston, Galloway, Hou, Sean W., Carpenter, Eileen S., Andren, Anthony C., Nwosu, Zeribe C., Cusmano, Nicholas, Wisner, Stephanie, Mbah, Nneka E., Shan, Mengrou, Das, Nupur K., Magnuson, Brian, Little, Andrew C., Savani, Milan R., Ramos, Johanna, Gao, Tina, Sastra, Stephen A., Palermo, Carmine F., Badgley, Michael A., Zhang, Li, Asara, John M., McBrayer, Samuel K., di Magliano, Marina Pasca, Crawford, Howard C., Shah, Yatrik M., Olive, Kenneth P., Lyssiotis, Costas A.“…We previously described a cytosolic aspartate aminotransaminase (GOT1)-driven pathway in pancreatic cancer used to maintain redox balance. Here, we sought to identify metabolic dependencies following GOT1 inhibition to exploit this feature of pancreatic cancer and to provide additional insight into regulation of redox metabolism. …”
Publicado 2021
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2005por Kunovsky, Lumir, Dite, Petr, Jabandziev, Petr, Dolina, Jiri, Vaculova, Jitka, Blaho, Martin, Bojkova, Martina, Dvorackova, Jana, Uvirova, Magdalena, Kala, Zdenek, Trna, Jan“…There is data (albeit not fully consistent) indicating modestly increased pancreatic cancer risk in H. pylori-positive patients. …”
Publicado 2021
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2006
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2007por Shimizu, Masayuki, Takayama, Shin, Kikuchi, Akiko, Arita, Ryutaro, Ono, Rie, Ishizawa, Kota, Ishii, Tadashi“…Aims: The present report aims to investigate the use of Kampo medicine for advanced pancreatic cancer patients in order to prolong survival. …”
Publicado 2021
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2008por Song, Libin, Qi, Simin, Hu, Wei, Fang, Zhixiao, Yu, Dehua, Liu, Teng, Wu, Jingni, Wu, Yangjun, Wu, Aiwei, Feng, Lanyun, Xie, Jing, Zhang, Bo, He, Wenguang, Ning, Zhouyu, Liu, Luming, Qin, Jiang-Jiang, Li, Shengli“…Pancreatic cancer is a highly aggressive cancer with an exceedingly low rate of response to treatments, which calls for comprehensive molecular characterization of pancreatic cancer cell lines (PCCLs). …”
Publicado 2021
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2009por Xu, Ming, Cui, Ran, Ye, Lunhe, Wang, Yongkun, Wang, Xujing, Zhang, Qiqi, Wang, Kaijing, Dong, Chunxiu, Le, Wenjun, Chen, BoEnlace del recurso
Publicado 2021
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2010“…The relationship between type 2 diabetes mellitus (T2DM) and pancreatic cancer (PC) is complex. Diabetes is a known risk factor for PC, and new-onset diabetes (NOD) could be an early manifestation of PC that may be facilitate the early diagnosis of PC. …”
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2011por Lu, Ye, Corradi, Chiara, Gentiluomo, Manuel, López de Maturana, Evangelina, Theodoropoulos, George E., Roth, Susanne, Maiello, Evaristo, Morelli, Luca, Archibugi, Livia, Izbicki, Jakob R., Sarlós, Patricia, Kiudelis, Vytautas, Oliverius, Martin, Aoki, Mateus Nóbrega, Vashist, Yogesh, van Eijck, Casper H. J., Gazouli, Maria, Talar-Wojnarowska, Renata, Mambrini, Andrea, Pezzilli, Raffaele, Bueno-de-Mesquita, Bas, Hegyi, Péter, Souček, Pavel, Neoptolemos, John P., Di Franco, Gregorio, Sperti, Cosimo, Kauffmann, Emanuele F., Hlaváč, Viktor, Uzunoğlu, Faik G., Ermini, Stefano, Małecka-Panas, Ewa, Lucchesi, Maurizio, Vanella, Giuseppe, Dijk, Frederike, Mohelníková-Duchoňová, Beatrice, Bambi, Franco, Petrone, Maria Chiara, Jamroziak, Krzysztof, Guo, Feng, Kolarova, Katerina, Capretti, Giovanni, Milanetto, Anna Caterina, Ginocchi, Laura, Loveček, Martin, Puzzono, Marta, van Laarhoven, Hanneke W. M., Carrara, Silvia, Ivanauskas, Audrius, Papiris, Konstantinos, Basso, Daniela, Arcidiacono, Paolo G., Izbéki, Ferenc, Chammas, Roger, Vodicka, Pavel, Hackert, Thilo, Pasquali, Claudio, Piredda, Maria L., Costello-Goldring, Eithne, Cavestro, Giulia Martina, Szentesi, Andrea, Tavano, Francesca, Włodarczyk, Barbara, Brenner, Hermann, Kreivenaite, Edita, Gao, Xin, Bunduc, Stefania, Vermeulen, Roel C. H., Schneider, Martin A., Latiano, Anna, Gioffreda, Domenica, Testoni, Sabrina G. G., Kupcinskas, Juozas, Lawlor, Rita T., Capurso, Gabriele, Malats, Núria, Campa, Daniele, Canzian, Federico“…Genetic factors play an important role in the susceptibility to pancreatic cancer (PC). However, established loci explain a small proportion of genetic heritability for PC; therefore, more progress is needed to find the missing ones. …”
Publicado 2021
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2012por KalantarMotamedi, Yasaman, Choi, Ran Joo, Koh, Siang-Boon, Bramhall, Jo L., Fan, Tai-Ping, Bender, Andreas“…Resistance to current therapies is common for pancreatic cancer and hence novel treatment options are urgently needed. …”
Publicado 2021
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2013por Nguyen, Nicholas D., Yu, Meifang, Reddy, Vinit Y., Acevedo-Diaz, Ariana C., Mesarick, Enzo C., Abi Jaoude, Joseph, Yuan, Min, Asara, John M., Taniguchi, Cullen M.“…The mechanisms of how these different inducers of mitochondrial fusion reduce pancreatic cancer growth are still unknown. Here, we characterized and compared the metabolic reprogramming of these three independent methods of inducing mitochondrial fusion in KPC cells: overexpression of Mfn2, genetic editing of Drp1, or treatment with leflunomide. …”
Publicado 2021
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2014“…This review focuses on new insights and therapeutic approaches that are dawning against pancreatic cancer: a neoplasm that arises in a central metabolic “hub” interfaced between the gut and the host.…”
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2015“…The research shows that the robot has a good clinical effect in the treatment of pancreatic cancer.…”
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2016
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2017“…SIMPLE SUMMARY: Pancreatic cancer has a very low survival rate and improved treatments are required. …”
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2018
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2019por Delvecchio, Francesca R., Fincham, Rachel E.A., Spear, Sarah, Clear, Andrew, Roy-Luzarraga, Marina, Balkwill, Frances R., Gribben, John G., Bombardieri, Michele, Hodivala-Dilke, Kairbaan, Capasso, Melania, Kocher, Hemant M.“…Here, we aim to investigate the structure and role of TLSs in human and murine pancreatic cancer. METHODS: Multicolor immunofluorescence and immunohistochemistry were used to fully characterize TLSs in human and murine (transgenic [KPC (Kras(G12D), p53(R172H), Pdx-1-Cre)] and orthotopic) pancreatic cancer. …”
Publicado 2021
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2020por Fazli, Hamid Reza, Moradzadeh, Maliheh, Mehrbakhsh, Zahra, Sharafkhah, Maryam, Masoudi, Sahar, Pourshams, Akram, Mohamadkhani, Ashraf“…BACKGROUND Pancreatic cancer is considered as the most deadly tumor among gastrointestinal cancers because of its poor prognosis. …”
Publicado 2021
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