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2361por Zheng, Zhaoxu, Zheng, Rongshou, He, Yutong, Sun, Xibin, Wang, Ning, Chen, Tianhui, Chen, Wanqing“…BACKGROUND: Despite having one of the highest mortality rates of all cancers, the risk factors of pancreatic cancer remain unclear. We assessed risk factors of pancreatic cancer in China. …”
Publicado 2016
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2362por Martinez, Emmanuelle, Silvy, Françoise, Fina, Fréderic, Bartoli, Marc, Krahn, Martin, Barlesi, Fabrice, Figarella-Branger, Dominique, Iovanna, Juan, Laugier, René, Ouaissi, Mehdi, Lombardo, Dominique, Mas, Eric“…Pancreatic cancer (PC) is a devastating disease progressing asymptomatically until death within months after diagnosis. …”
Publicado 2015
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2363por Pothula, Srinivasa P, Xu, Zhihong, Goldstein, David, Biankin, Andrew V, Pirola, Romano C, Wilson, Jeremy S, Apte, Minoti V“…BACKGROUND: Pancreatic stellate cells (PSCs, which produce the stroma of pancreatic cancer (PC)) interact with cancer cells to facilitate PC growth. …”
Publicado 2016
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2364por Zhu, Liang, Shi, Xiaohua, Xue, Huadan, Wu, Huanwen, Chen, Ge, Sun, Hao, He, Yonglan, Jin, Zhengyu, Liang, Zhiyong, Zhang, Zhuoli“…This study aimed to determine whether changes in contrast-enhanced computed tomography (CT) parameters could predict postsurgery overall and progression-free survival (PFS) in pancreatic cancer patients. Seventy-nine patients with a final pathological diagnosis of pancreatic adenocarcinoma were included in this study from June 2008 to August 2012. …”
Publicado 2016
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2365“…Tumor-infiltrating immune cells, which are found in nearly all cancers, including PDAC, often fail to eliminate the tumor, but conversely can promote its progression by altering the tumor microenvironment. Pancreatic cancer cells are able to attract polymorphonuclear neutrophils (PMN) via tumor secreted chemokines and in human PDAC, PMN infiltrates can be observed in the vicinity of tumor cells and in the desmoplastic tumor stroma, which correlate with undifferentiated tumor growth and poor prognosis. …”
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2366por Ma, Yanfen, Hu, Jian, Zhang, Ning, Dong, Xinran, Li, Ying, Yang, Bo, Tian, Weidong, Wang, Xiaoqin“…Pancreatic cancer is the leading cause of death from solid malignancies worldwide. …”
Publicado 2016
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2367por Azoulay, Laurent, Filion, Kristian B, Platt, Robert W, Dahl, Matthew, Dormuth, Colin R, Clemens, Kristin K, Durand, Madeleine, Juurlink, David N, Targownik, Laura E, Turin, Tanvir C, Paterson, J Michael, Ernst, Pierre“…Objective To determine whether the use of incretin based drugs compared with sulfonylureas is associated with an increased risk of incident pancreatic cancer in people with type 2 diabetes. Design Population based cohort. …”
Publicado 2016
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2369“…BACKGROUND & OBJECTIVE: The results of epidemiologic studies on the relationship between the coffee consumption and pancreatic cancer risk were inconsistent. Thus, we performed an update meta-analysis of cohort studies to quantitatively summarize the association between coffee consumption and pancreatic cancer risk. …”
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2370por Ponnurangam, Sivapriya, Dandawate, Prasad R., Dhar, Animesh, Tawfik, Ossama W., Parab, Rajashri R., Mishra, Prabhu Dutt, Ranadive, Prafull, Sharma, Rajiv, Mahajan, Girish, Umar, Shahid, Weir, Scott J., Sugumar, Aravind, Jensen, Roy A., Padhye, Subhash B., Balakrishnan, Arun, Anant, Shrikant, Subramaniam, Dharmalingam“…Quinomycin treatment resulted in significant inhibition of proliferation and colony formation in pancreatic cancer cell lines, but not in normal pancreatic epithelial cells. …”
Publicado 2015
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2371por Reynoird, Nicolas, Mazur, Pawel K., Stellfeld, Timo, Flores, Natasha M., Lofgren, Shane M., Carlson, Scott M., Brambilla, Elisabeth, Hainaut, Pierre, Kaznowska, Ewa B., Arrowsmith, Cheryl H., Khatri, Purvesh, Stresemann, Carlo, Gozani, Or, Sage, Julien“…These findings uncover a pivotal role for SMYD2 in promoting pancreatic cancer.…”
Publicado 2016
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2372“…The present study aimed to screen for potential genes and subnetworks associated with pancreatic cancer (PC) using the gene expression profile. …”
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2373por Schirmer, Markus A., Lüske, Claudia M., Roppel, Sebastian, Schaudinn, Alexander, Zimmer, Christian, Pflüger, Ruben, Haubrock, Martin, Rapp, Jacobe, Güngör, Cenap, Bockhorn, Maximilian, Hackert, Thilo, Hank, Thomas, Strobel, Oliver, Werner, Jens, Izbicki, Jakob R., Johnsen, Steven A., Gaedcke, Jochen, Brockmöller, Jürgen, Ghadimi, B. Michael“…Likewise, RNAi-mediated WWOX knockdown in pancreatic cancer cells confirmed differential cytostatic drug sensitivity. …”
Publicado 2016
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2374por Huang, Xiu-yan, Huang, Zi-li, Yang, Ju-hong, Xu, Yong-hua, Sun, Jiu-Song, Zheng, Qi, Wei, Chunyao, Song, Wei, Yuan, ZhouEnlace del recurso
Publicado 2016
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2375por Vanova, K., Boukalova, S., Gbelcova, H., Muchova, L., Neuzil, J., Gurlich, R., Ruml, T., Vitek, L.“…BACKGROUND: Pancreatic cancer is recognized as one of the most fatal tumors due to its aggressiveness and resistance to therapy. …”
Publicado 2016
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2376por Tao, Lian-yuan, Zhang, Ling-fu, Xiu, Dian-rong, Yuan, Chun-hui, Ma, Zhao-lai, Jiang, Bin“…BACKGROUND: K-ras gene mutations are common in patients with pancreatic cancer (PC); however, their prognostic value for PC remains inconclusive. …”
Publicado 2016
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2377por Nielsen, Sebastian R, Quaranta, Valeria, Linford, Andrea, Emeagi, Perpetua, Rainer, Carolyn, Santos, Almudena, Ireland, Lucy, Sakai, Takao, Sakai, Keiko, Kim, Yong-Sam, Engle, Dannielle, Campbell, Fiona, Palmer, Daniel, Ko, Jeong Heon, Tuveson, David A., Hirsch, Emilio, Mielgo, Ainhoa, Schmid, Michael CEnlace del recurso
Publicado 2016
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2378por Wu, Xiaoqing, Tang, Wenhua, Marquez, Rebecca T., Li, Ke, Highfill, Chad A., He, Fengtian, Lian, Jiqin, Lin, Jiayuh, Fuchs, James R., Ji, Min, Li, Ling, Xu, Liang“…Chemo/radio-therapy resistance to the deadly pancreatic cancer is mainly due to the failure to kill pancreatic cancer stem cells (CSCs). …”
Publicado 2016
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2379por Jiang, Hong, Hegde, Samarth, Knolhoff, Brett L., Zhu, Yu, Herndon, John M., Meyer, Melissa A., Nywening, Timothy M., Hawkins, William G., Shapiro, Irina M., Weaver, David T., Pachter, Jonathan A., Wang-Gillam, Andrea, DeNardo, David G.Enlace del recurso
Publicado 2016
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2380“…Diabetes mellitus (DM) and pancreatic cancer are intimately related, as approximately 85% of patients diagnosed with pancreatic cancer have impaired glucose tolerance or even DM. …”
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