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2541por Moertl, Simone, Payer, Sarah, Kell, Rosemarie, Winkler, Klaudia, Anastasov, Natasa, Atkinson, Michael J.“…Pancreatic cancer has a poor prognosis. New treatment options are urgently required to improve patient outcomes. …”
Publicado 2019
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2542“…We conclude that resveratrol acts as an effective antioxidant in reversing the nicotine induced pancreatic cancer cell proliferation.…”
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2543por van Veldhuisen, Eran, van den Oord, Claudia, Brada, Lilly J., Walma, Marieke S., Vogel, Jantien A., Wilmink, Johanna W., del Chiaro, Marco, van Lienden, Krijn P., Meijerink, Martijn R., van Tienhoven, Geertjan, Hackert, Thilo, Wolfgang, Christopher L., van Santvoort, Hjalmar, Groot Koerkamp, Bas, Busch, Olivier R., Molenaar, I. Quintus, van Eijck, Casper H., Besselink, Marc G.“…Locally advanced pancreatic cancer (LAPC) has several definitions but essentially is a nonmetastasized pancreatic cancer, in which upfront resection is considered not beneficial due to extensive vascular involvement and consequent high chance of a nonradical resection. …”
Publicado 2019
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2544por Ghidini, Michele, Petrillo, Angelica, Salati, Massimiliano, Khakoo, Shelize, Varricchio, Antonio, Tomasello, Gianluca, Grossi, Francesco, Petrelli, Fausto“…Here we review the literature on surgical and locoregional approaches including radiofrequency ablation, irreversible electroporation, and stereotactic body radiation, and focus on patients with hepatic oligometastatic pancreatic cancer. We provide a summary regarding survival outcomes, morbidity and mortality and discuss selection criteria that may be useful to predict the best outcomes for such strategies.…”
Publicado 2019
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2545“…Pancreatic cancer represents a major challenge in oncology. …”
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2546por Matsuda, Yoko, Inoue, Yosuke, Hiratsuka, Makiko, Kawakatsu, Shoji, Arai, Tomio, Matsueda, Kiyoshi, Saiura, Akio, Takazawa, Yutaka“…This study included 82 localized pancreatic cancer, 40 of whom were treated with neoadjuvant therapy (NAT) using four courses of gemcitabine plus nab-paclitaxel (GnP) followed by pancreatectomy (GnP group). …”
Publicado 2019
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2547por Gilles, Maud-Emmanuelle, Hao, Liangliang, Brown, Kaelyn, Lim, Jihoon, Bhatia, Sangeeta N., Slack, Frank J.“…Developing new targeted therapy for pancreatic cancer is one of the major current challenges in cancer research. …”
Publicado 2019
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2548por Matsuda, Yoko, Fujii, Yuko, Matsukawa, Miho, Ishiwata, Toshiyuki, Nishimura, Makoto, Arai, Tomio“…Our previous study reported the safety and efficacy of EUS-guided fine-needle injection (EUS-FNI) of STNM01, a double-stranded RNA oligonucleotide that specifically represses CHST15, for use in patients with pancreatic cancer. The present study aimed to determine the expression and clinicopathological characteristics of CHST15 in pancreatic cancer. …”
Publicado 2019
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2549por Karamitopoulou, Eva“…Pancreatic cancer is a lethal disease, with fewer than 7% of patients surviving beyond 5 years following diagnosis. …”
Publicado 2019
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2550“…BACKGROUND: Previous studies revealed somatic mutations of the cationic trypsinogen gene (PRSS1) in patients with chronic pancreatitis and pancreatic cancer. However, whether PRSS1 mutations trigger pancreatic cancer and/or promote malignant proliferation and metastasis in pancreatic cancer remains largely unclear, as well as the potential underlying mechanisms. …”
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2551por Luchini, Claudio, Pea, Antonio, Yu, Jun, He, Jin, Salvia, Roberto, Riva, Giulio, Weiss, Matthew J., Bassi, Claudio, Cameron, John L., Hruban, Ralph H., Goggins, Michael, Wolfgang, Christopher L., Scarpa, Aldo, Wood, Laura D., Lawlor, Rita T.Enlace del recurso
Publicado 2018
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2552por Linnebacher, Alica, Mayer, Philipp, Marnet, Nicole, Bergmann, Frank, Herpel, Esther, Revia, Steffie, Yin, Libo, Liu, Li, Hackert, Thilo, Giese, Thomas, Herr, Ingrid, Gaida, Matthias M.Enlace del recurso
Publicado 2019
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2553por Zhang, Ying-Bo, Fei, Hong-Xin, Guo, Jia, Zhang, Xiao-Jie, Wu, Shu-Liang, Zhong, Li-Li“…Inhibition of the Hh signaling pathway is a potential therapeutic target for pancreatic cancer. The aim of the present study was to investigate the effects of dauricine in a pancreatic cancer BxPC-3 ×enograft animal model and examine the underlying molecular mechanisms through Hh signaling pathway. …”
Publicado 2019
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2554“…Approximately 25% of patients diagnosed with pancreatic cancer present with non-metastatic resectable or borderline resectable disease. …”
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2555“…The Nim-nano exhibited sustained release of Nim for more than 6 days in PBS (pH 7.4) and showed two- to three-fold enhanced cytotoxicity in breast and pancreatic cancer cell lines compared with free Nim. CONCLUSION: The Nim-nano formulation has great potential for treatment of cancers, such as pancreatic and breast cancer. …”
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2556por Dwarte, Tanya, McKay, Skye, Johns, Amber, Tucker, Katherine, Spigelman, Allan D., Williams, David, Stoita, Alina“…BACKGROUND: Pancreatic cancer (PC) is an aggressive disease with a dismal 5-year survival rate. …”
Publicado 2019
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2557por Zhong, Xiaoling, Pons, Marianne, Poirier, Christophe, Jiang, Yanlin, Liu, Jianguo, Sandusky, George E., Shahda, Safi, Nakeeb, Attila, Schmidt, C. Max, House, Michael G., Ceppa, Eugene P., Zyromski, Nicholas J., Liu, Yunlong, Jiang, Guanglong, Couch, Marion E., Koniaris, Leonidas G., Zimmers, Teresa A.Enlace del recurso
Publicado 2019
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2558“…BACKGROUND: Pancreatic cancer is one of the most lethal malignancies due to frequent late diagnosis, aggressive tumor growth and metastasis formation. …”
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2559por Tsujimoto, Akiko, Sudo, Kentaro, Nakamura, Kazuyoshi, Kita, Emiri, Hara, Ryusuke, Takayama, Wataru, Ishii, Hiroshi, Yamaguchi, Taketo“…Overall survival in a phase III study for metastatic pancreatic cancer has significantly improved with gemcitabine (GEM) plus nab-paclitaxel. …”
Publicado 2019
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2560Myeloid-Derived Suppressor Cells and Pancreatic Cancer: Implications in Novel Therapeutic Approachespor Thyagarajan, Anita, Alshehri, Mamdouh Salman A., Miller, Kelly L.R., Sherwin, Catherine M., Travers, Jeffrey B., Sahu, Ravi P.Enlace del recurso
Publicado 2019
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