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“…Henceforth, developing diagnostic procedures for its early detection, understanding pancreatic cancer-linked mechanisms, and various therapeutic strategies are crucial. …”
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“…BACKGROUND: Pancreatic cancer is gastrointestinal cancer with a poor prognosis. …”
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“…SIMPLE SUMMARY: The prognosis of pancreatic cancer is always serious. In most cases, the cancer is diagnosed at an advanced stage. …”
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“…Despite the development of newer oncological treatment, the survival of patients with pancreatic cancer (PC) remains poor. Recent studies have identified exosomes as essential mediators of intercellular communications and play a vital role in tumor initiation, metastasis and chemoresistance. …”
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“…SIMPLE SUMMARY: The gut microbiota is involved in homeostasis but can facilitate the insurgence of diseases including pancreatic cancer when altered. These gut microbes modulate the metabolism of bile acids, which are found to be abnormal in pancreatic cancer and diseases considered risk factors for it. …”
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“…Pancreatic cancer is a leading cause of cancer-related death, with a poor overall survival rate. …”
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“…Although immunotherapy has proved to be a very efficient therapeutic strategy for many types of tumors, the results for pancreatic cancer (PC) have been very poor. Indeed, chemotherapy remains the standard treatment for this tumor in the advanced stage. …”
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“…Pancreatic cancer, in most cases being pancreatic ductal adenocarcinoma (PDAC), is one of the most lethal cancers with a median survival time of less than 6 months. …”
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“…Pancreatic cancer, one of the diseases of the elderly, has dismal prognosis, demanding major surgery with high risk and life quality problems, especially in the elderly. …”
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“…ABSTRACT: Pancreatic cancer is one of the most prothrombotic malignancies. …”
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“…OBJECTIVE: Accurate, easily accessible and economically viable cancer diagnostic tools are pivotal in improving the abysmal 5% survival rate of pancreatic cancer. METHODS: A novel, affordable, non‐invasive diagnostic method has been developed by combining measurement precision of infrared spectroscopy with classification using machine learning tools. …”
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“…SIMPLE SUMMARY: Pancreatic cancer (PCa) is a highly aggressive and deadly form of cancer with a low five-year survival rate. …”
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“…METHODS: In this hospital-based case-control study, 194 patients with pancreatic cancer were compared to 582 age and sex-matched patients with non-neoplastic conditions to examine the association between aspirin use and risk of pancreatic cancer. …”
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“…There is also some evidence that they may increase the risk of pancreatic cancer. We report results from a population-based case–control study of 486 incident cases of pancreatic cancer and 3,596 age- and sex-matched controls. …”
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“…As with other solid tumors, the growth and metastasis of pancreatic cancer is critically dependent on tumor angiogenesis. …”
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“…We also present other viewpoints on the origin of pancreatic cancer histogenesis and outline certain areas of disagreement. …”
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