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281por Ikeda, N, Adachi, M, Taki, T, Huang, C, Hashida, H, Takabayashi, A, Sho, M, Nakajima, Y, Kanehiro, H, Hisanaga, M, Nakano, H, Miyake, M“…To evaluate whether angiogenic factors are of clinical relevance to actual human pancreatic cancers, we studied the intratumoral microvessel density (IMD), and PD-ECGF, VEGF protein expression in 40 pancreatic cancers using immunohistochemistry. …”
Publicado 1999
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282por Schernhammer, E S, Michaud, D S, Leitzmann, M F, Giovannucci, E, Colditz, G A, Fuchs, C S“…We examined the relation between gallstones, cholecystectomy, and the development of pancreatic cancer in the Nurses' Health Study and the Health Professionals Follow-up Study. …”
Publicado 2002
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283por Stocken, D D, Hassan, A B, Altman, D G, Billingham, L J, Bramhall, S R, Johnson, P J, Freemantle, N“…Pancreatic cancer is the fifth most common cause of cancer death. …”
Publicado 2008
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284por Harsha, H. C., Kandasamy, Kumaran, Ranganathan, Prathibha, Rani, Sandhya, Ramabadran, Subhashri, Gollapudi, Sashikanth, Balakrishnan, Lavanya, Dwivedi, Sutopa B., Telikicherla, Deepthi, Selvan, Lakshmi Dhevi N., Goel, Renu, Mathivanan, Suresh, Marimuthu, Arivusudar, Kashyap, Manoj, Vizza, Robert F., Mayer, Robert J., DeCaprio, James A., Srivastava, Sudhir, Hanash, Samir M., Hruban, Ralph H., Pandey, Akhilesh“…Akhilesh Pandey and colleagues describe a compendium of potential biomarkers that can be systematically validated by the pancreatic cancer community.…”
Publicado 2009
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285por Brune, Kieran A., Lau, Bryan, Palmisano, Emily, Canto, Marcia, Goggins, Michael G., Hruban, Ralph H., Klein, Alison P.“…BACKGROUND: Young-onset cancer is a hallmark of many familial cancer syndromes, yet the implications of young-onset disease in predicting risk of pancreatic cancer among familial pancreatic cancer (FPC) kindred members remain unclear. …”
Publicado 2010
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286
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287“…Research in chemotherapy for metastatic disease has made only modest progress and the standard of care remains the purine analog gemcitabine. For resectable pancreatic cancer, presumed micrometastases provide the rationale for adjuvant chemotherapy and chemoradiation (CRT) to supplement surgical management. …”
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288“…BACKGROUND: Pancreatic cancer is one of the most aggressive human tumors due to its high potential of local invasion and metastasis. …”
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289“…Pancreatic cancer is a malignancy of poor prognosis which is mostly diagnosed at advanced stages. …”
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290
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291“…BACKGROUND: Surgery appears to be an underutilized treatment option for pancreatic cancer. Nihilistic physician attitudes may be partly responsible. …”
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292por Liszka, Łukasz, Pająk, Jacek, Mrowiec, Sławomir, Zielińska-Pająk, Ewa, Gołka, Dariusz, Lampe, Paweł“…Early onset pancreatic cancer (EOPC) constitutes less than 5% of all newly diagnosed cases of pancreatic cancer (PC). …”
Publicado 2011
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293por Chen, Qingfeng, Wang, Zhengkun, Zhang, Kejun, Liu, Xiaoyi, Cao, Weihong, Zhang, Lei, Zhang, Shuhua, Yan, Bomin, Wang, Yaoguang, Xia, Chunping“…OBJECTIVE: To measure clusterin expression in pancreatic cancer tissues and cell lines and to evaluate whether clusterin confers resistance to gmcitabine in pancreatic cancer cells. …”
Publicado 2011
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294“…5-fluorouracil (5-FU) is widely used in chemotherapy for gastric and colorectal cancer, but gemcitabine (GEM), and not 5-FU, is approved as a standard drug for use in pancreatic cancer. Interindividual variation in the enzyme activity of the GEM metabolic pathway can affect the extent of GEM metabolism and the efficacy of GEM chemotherapy. …”
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295por Rizzato, Cosmeri, Campa, Daniele, Giese, Nathalia, Werner, Jens, Rachakonda, P. Sivaramakrishna, Kumar, Rajiv, Schanné, Michaela, Greenhalf, William, Costello, Eithne, Khaw, Kay-tee, Key, Tim J., Siddiq, Afshan, Lorenzo-Bermejo, Justo, Burwinkel, Barbara, Neoptolemos, John P., Büchler, Markus W., Hoheisel, Jörg D., Bauer, Andrea, Canzian, Federico“…Pancreatic cancer has one of the worst mortality rates of all cancers. …”
Publicado 2011
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296por Colvin, Emily K., Susanto, Johana M., Kench, James G., Ong, Vivienna N., Mawson, Amanda, Pinese, Mark, Chang, David K., Rooman, Ilse, O'Toole, Sandra A., Segara, Davendra, Musgrove, Elizabeth A., Sutherland, Robert L., Apte, Minoti V., Scarlett, Christopher J., Biankin, Andrew V.“…BACKGROUND: Activation of embryonic signaling pathways quiescent in the adult pancreas is a feature of pancreatic cancer (PC). These discoveries have led to the development of novel inhibitors of pathways such as Notch and Hedgehog signaling that are currently in early phase clinical trials in the treatment of several cancer types. …”
Publicado 2011
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297por Andrén-Sandberg, ÅkeEnlace del recurso
Publicado 2011
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298por Andrén-Sandberg, ÅkeEnlace del recurso
Publicado 2011
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299por Wang, De-shen, Wang, Zhi-qiang, Zhang, Le, Qiu, Miao-zhen, Luo, Hui-yan, Ren, Chao, Zhang, Dong-sheng, Wang, Feng-hua, Li, Yu-hong, Xu, Rui-hua“…BACKGROUND: The development of pancreatic cancer is a process in which genes interact with environmental factors. …”
Publicado 2012
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300por Kirkegaard, Jakob“…But what is the trend regarding pancreatic cancer? OBJECTIVE: To determine the incidence of pancreatic cancer (PC) in Greenland compared with Denmark in the period 2000–2010. …”
Publicado 2012
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