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  1. 3021
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    In vivo inhibition of cysteine proteinases delays the onset of growth of human pancreatic cancer explants
  2. 3022
    “…We found that hypoxia enhanced the expression of autocrine motility factor mRNA in various cancer cells and also enhanced the random motility of pancreatic cancer cells. Autocrine motility factor inhibitors abrogated the increase of motility under hypoxic conditions. …”
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    Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells
  3. 3023
    “…Pancreatic cancer is associated with a very poor prognosis; however, in selected patients, resection may improve survival. …”
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    Benefits of specialisation in the management of pancreatic cancer: results of a Scottish population-based study
  4. 3024
    por Ge, Guangtao, Wong, G William
    Publicado 2008
    “…BACKGROUND: Pancreatic cancer is the fourth leading cause of cancer death in the United States. …”
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    Classification of premalignant pancreatic cancer mass-spectrometry data using decision tree ensembles
  5. 3025
    “…Pancreatic cancer has one of the highest mortalities among all malignancies and there is an urgent need for new therapy. …”
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    FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer
  6. 3026
    “…BACKGROUND: Pancreatic cancer retains a poor prognosis among the gastrointestinal cancers. …”
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    Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer
  7. 3027
    “…A total of 50 patients with advanced pancreatic cancer were enrolled in a phase II study of bevacizumab 15 mg kg(−1), capecitabine 1300 mg m(−2) daily for 2 weeks and gemcitabine 1000 mg m(−2) weekly 2 times; cycles were repeated every 21 days. …”
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    Bevacizumab combined with gemcitabine and capecitabine for advanced pancreatic cancer: a phase II study
  8. 3028
    “…Pancreatic cancer screening has been hampered by the high rate of complications associated with interrogating the pancreas. …”
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    Investigating Population Risk Factors of Pancreatic Cancer by Evaluation of Optical Markers in the Duodenal Mucosa
  9. 3029
    “…We investigated the in vitro activity of the most potent antiresorptive BP, zoledronic acid (ZOL), on the growth and survival of three human pancreatic cancer (PC) cell lines (BxPC-3, CFPAC-1 and PANC-1). …”
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    Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro
  10. 3030
    “…BACKGROUND: Adrenomedullin (AM) is highly expressed in pancreatic cancer and stimulates pancreatic cancer cells leading to increased tumor growth and metastasis. …”
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    The ADMR Receptor Mediates the Effects of Adrenomedullin on Pancreatic Cancer Cells and on Cells of the Tumor Microenvironment
  11. 3031
    “…BACKGROUND: The combination of gemcitabine (GEM) and S-1, an oral 5-fluorouracil (5-FU) derivative, has been shown to be a promising regimen for patients with unresectable pancreatic cancer. METHODS: Six patients with advanced pancreatic cancer were enrolled in this pharmacokinetics (PK) study. …”
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    Plasma pharmacokinetics after combined therapy of gemcitabine and oral S-1 for unresectable pancreatic cancer
  12. 3032
    “…In patients with advanced pancreatic cancer (APC), phase angle, determined by bio-electrical impedance analysis (BIA), seems to be a survival predictor. …”
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    Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study
  13. 3033
    “…BACKGROUND: Our understanding of the mechanism regulating pancreatic cancer metastatic phenotype is limited. We analyzed the role of RHOA and PRKCZ in the motility attitude of two subclones of the pancreatic adenocarcinoma cell line SUIT-2 (S2), with different in vivo metastatic potential in nude mice: S2-m with a low metastatic potential and highly metastatic S2-CP9 using RHOA and PRKCZ cell-permeable inhibitory peptides. …”
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    RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones
  14. 3034
    “…INTRODUCTION: Pancreatic cancer (PC) is the sixth leading cause of cancer death in Australia and the fourth in the United States, yet research in PC is lagging behind that in other cancers associated with a high disease burden. …”
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    Defining research priorities for pancreatic cancer in Australia: results of a consensus development process
  15. 3035
    “…BACKGROUND: Studies evaluating vitamin D status in relation to pancreatic cancer risk have yielded inconsistent results. …”
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    Predicted vitamin D status and pancreatic cancer risk in two prospective cohort studies
  16. 3036
    “…Pancreatic cancer is the eighth most common cause of death from cancer in the world, for which palliative treatments are not effective and frequently accompanied by severe side effects. …”
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    Use of H19 Gene Regulatory Sequences in DNA-Based Therapy for Pancreatic Cancer
  17. 3037
    “…The capacity of a panel of four pancreatic cancer cell lines (PANC-1, CFPAC-1, PancTu-1 and PSN-1) to form spheres was tested. …”
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    Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells
  18. 3038
    “…CONCLUSIONS: The ACEIs/ARBs in combination with gemcitabine might improve clinical outcomes in patients with advanced pancreatic cancer. Prospective trials are needed to test this hypothesis.…”
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    Inhibition of renin–angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine
  19. 3039
    “…However, the role that miRNAs play in pancreatic cancer remains to be determined. The purpose of this study was to investigate aberrantly expressed miRNAs in pancreatic cancer tissues and demonstrate their roles in disease progression. …”
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    Dysregulation of miR-15a and miR-214 in human pancreatic cancer
  20. 3040
    “…The utility of repeat EUS in patients with suspicion for pancreatic cancer after non-diagnostic EUS-FNA study is not well established. …”
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    The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer
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