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  1. 3061
    por Yu, Ji Hoon, Kim, Hyeyoung
    Publicado 2012
    “…This review discusses the possible role of the JAK/STAT pathway in the pathogenesis of pancreatitis and pancreatic cancer in response to oxidative stress.…”
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    Role of Janus Kinase/Signal Transducers and Activators of Transcription in the Pathogenesis of Pancreatitis and Pancreatic Cancer
  2. 3062
    “…AIM: To assess pain intensity levels and quality of life of pancreatic cancer patients after videothoracoscopic splanchnicectomy. …”
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    Assessment of quality of life in patients with non-operated pancreatic cancer after videothoracoscopic splanchnicectomy
  3. 3063
    “…CONCLUSIONS/SIGNIFICANCE: Rapid growth is one characteristic of pancreatic cancer. Our data indicates that the TRAF2/NIK/NF-κB2 pathway regulates PDAC cell tumorigenicity and could be a valuable target for therapy of this cancer.…”
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    Downregulation of TRAF2 Mediates NIK-Induced Pancreatic Cancer Cell Proliferation and Tumorigenicity
  4. 3064
    “…BACKGROUND: Pancreatic cancer is one of the deadliest cancers with a 5-year survival rate of 6%. …”
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    Mechanistic Evaluation of a Novel Small Molecule Targeting Mitochondria in Pancreatic Cancer Cells
  5. 3065
    “…CONCLUSIONS: The authors demonstrate that HA impedes the intratumoral vasculature in PDA and propose that its enzymatic depletion be explored as a means to improve drug delivery and response in patients with pancreatic cancer.…”
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    Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
  6. 3066
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    The Rescue of miR-148a Expression in Pancreatic Cancer: An Inappropriate Therapeutic Tool
  7. 3067
    “…BACKGROUND: In the present retrospective analysis we analysed the therapeutic outcome of a set of patients, who were treated with chemoradiation (CRT) for recurrent pancreatic cancer (RPC) in a single institution. PATIENTS AND METHODS: Forty-one patients had a history of primary resection for pancreatic cancer. …”
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    Chemoradiation in patients with isolated recurrent pancreatic cancer - therapeutical efficacy and probability of re-resection
  8. 3068
    “…The parameters of the obtained excellent fit suggest that age of pancreatic cancer presentation has a time shift about 17 years and five mutations are needed for pancreatic cells to become malignant.…”
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    Basic Equations and Computing Procedures for Frailty Modeling of Carcinogenesis: Application to Pancreatic Cancer Data
  9. 3069
    “…Sixteen studies containing 1,308 advanced pancreatic cancer patients treated with gemcitabine plus erlotinib were included. …”
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    Gemcitabine Plus Erlotinib for Advanced Pancreatic Cancer: A Systematic Review with Meta-Analysis
  10. 3070
    “…BACKGROUND: The rate of microscopic incomplete resections of gastrointestinal cancers including pancreatic cancer has not changed considerably over the past years. …”
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    Tissue Tolerable Plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo
  11. 3071
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    Enhancing sorafenib-mediated sensitization to gemcitabine in experimental pancreatic cancer through EMAP II
  12. 3072
    “…Pancreatic cancer remains one of the most lethal and poorly understood human malignancies and will continue to be a major unsolved health problem in the 21(st) century. …”
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    Mechanisms of resistance to chemotherapeutic and anti-angiogenic drugs as novel targets for pancreatic cancer therapy
  13. 3073
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    Glutamine supports pancreatic cancer growth through a Kras-regulated metabolic pathway
  14. 3074
    “…METHODS: We retrospectively analyzed the medical records of 75 patients who received first-line chemotherapy for pancreatic cancer between April 2006 and September 2011. …”
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    Treatment outcome of advanced pancreatic cancer patients who are ineligible for a clinical trial
  15. 3075
    “…PURPOSE: Tumor invasion to the portal vein (PV) or superior mesenteric vein (SMV) can be encountered during the surgery for pancreatic cancer. Venous reconstruction is required, but the optimal surgical methods and conduits remain in controversies. …”
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    Reconstruction of portal vein and superior mesenteric vein after extensive resection for pancreatic cancer
  16. 3076
    “…Moreover, in vivo studies capsaicin effectively inhibited the growth and metabolism of pancreatic cancer and prolonged the survival time of pancreatic cancer xenograft tumor-induced mice. …”
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    Involvement of Endoplasmic Reticulum Stress in Capsaicin-Induced Apoptosis of Human Pancreatic Cancer Cells
  17. 3077
    “…These data suggest that CAP could be considered as an alternative to GEM in future, rationally designed, combination treatment strategies for advanced pancreatic cancer.…”
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    Anti-Tumour Efficacy of Capecitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer
  18. 3078
    “…Altogether, these alterations of pancreatic cancer cell metabolism mediated by cannabinoids result in a strong induction of autophagy and in the inhibition of cell growth.…”
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    Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells
  19. 3079
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    SBRT in unresectable advanced pancreatic cancer: preliminary results of a mono-institutional experience
  20. 3080
    “…Traditional post-surgical chemotherapy for pancreatic cancer is notorious for its devastating side effects due to the high dosage required. …”
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    Drug-eluting scaffold to deliver chemotherapeutic medication for management of pancreatic cancer after surgery
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