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3101“…Pancreatic cancer is a major health concern worldwide and, despite the attempts at management, the prognosis of patients with metastatic pancreatic cancer remains poor, with a median survival of a few months. …”
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3102por DUONG, HONG-QUAN, YI, YONG WEON, KANG, HYO JIN, HONG, YOUNG BIN, TANG, WENXI, WANG, ANTAI, SEONG, YEON-SUN, BAE, INSOO“…Additionally, the combinatorial effect of PIK-75 and gemcitabine was evaluated in human pancreatic cancer cell lines and a xenograft model. PIK-75 reduced NRF2 protein levels and activity to regulate its target gene expression through proteasome-mediated degradation of NRF2 in human pancreatic cancer cell lines. …”
Publicado 2013
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3103“…BACKGROUND: Previous epidemiologic studies have reported inconsistent results between parity and pancreatic cancer (PC) risk. To our knowledge, a comprehensive and quantitative assessment of this association has not been conducted. …”
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3104por Wang, Xiaohui, Xing, Xiaohong, Zhang, Bingbo, Liu, Fengjun, Cheng, Yingsheng, Shi, Donglu“…When conjugated with near-infrared fluorescent dye and monoclonal antibody, the (dye)BSA·SPION-monoclonal antibody bioconjugates showed excellent targeting capability with minimal nonspecific binding in the bimodal imaging of pancreatic cancer cells. The experimental approach is facile, environmentally benign, and straightforward, which presents great promise in early cancer diagnosis.…”
Publicado 2014
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3105por Huggett, M T, Jermyn, M, Gillams, A, Illing, R, Mosse, S, Novelli, M, Kent, E, Bown, S G, Hasan, T, Pogue, B W, Pereira, S P“…BACKGROUND: Patients with pancreatic cancer have a poor prognosis apart from the few suitable for surgery. …”
Publicado 2014
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3106por Xue, Peng, Kanai, Masashi, Mori, Yukiko, Nishimura, Takafumi, Uza, Norimitsu, Kodama, Yuzo, Kawaguchi, Yoshiya, Takaori, Kyoichi, Matsumoto, Shigemi, Uemoto, Shinji, Chiba, Tsutomu“…We aimed to determine the prognostic value of NLR in patients with advanced pancreatic cancer (APC) following palliative chemotherapy. …”
Publicado 2014
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3107por Mace, Thomas A, Pitaressi, Jason, Shakya, Reena, Frankel, Wendy, Eubank, Tim, Bekaii-Saab, Tanios, Bloomston, Mark, Phelps, Mitch, Ludwig, Thomas, Ostrowski, Michael, Lesinski, Gregory BEnlace del recurso
Publicado 2013
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3108por Shi, Chanjuan, Washington, M. Kay, Chaturvedi, Rupesh, Drosos, Yiannis, Revetta, Frank L., Weaver, Connie J., Buzhardt, Emily, Yull, Fiona E., Blackwell, Timothy S., Sosa-Pineda, Beatriz, Whitehead, Robert H., Beauchamp, R. Daniel, Wilson, Keith T., Means, Anna L.“…Pancreatic cancer occurs in the setting of a profound fibrotic microenvironment that often dwarfs the actual tumor. …”
Publicado 2014
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3109por Li, Ang, Morton, Jennifer P., Ma, YaFeng, Karim, Saadia A., Zhou, Yan, Faller, William J., Woodham, Emma F., Morris, Hayley T., Stevenson, Richard P., Juin, Amelie, Jamieson, Nigel B., MacKay, Colin J., Carter, C. Ross, Leung, Hing Y., Yamashiro, Shigeko, Blyth, Karen, Sansom, Owen J., Machesky, Laura M.“…Its levels in human PDAC correlate with outcomes and time to recurrence, indicating it might be a marker or therapeutic target for pancreatic cancer.…”
Publicado 2014
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3110por Proctor, Angela, Herrera-Loeza, S. Gabriela, Wang, Qunzhao, Lawrence, David S., Yeh, Jen Jen, Allbritton, Nancy L.“…The system was validated in three model pancreatic cancer cell lines before being applied to primary cells from human pancreatic adenocarcinomas propagated in nude mice. …”
Publicado 2014
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3111por Cabrera, M. Carla, Tilahun, Estifanos, Nakles, Rebecca, Diaz-Cruz, Edgar S., Charabaty, Aline, Suy, Simeng, Jackson, Patrick, Ley, Lisa, Slack, Rebecca, Jha, Reena, Collins, Sean P., Haddad, Nadim, Kallakury, Bhaskar V. S., Schroeder, Timm, Pishvaian, Michael J., Furth, Priscilla A.“…Pancreatic stellate cells are a key mediator of the pancreatic matrix and they promote progression and invasion of pancreatic cancer by increasing cell proliferation and offering protection against therapeutic interventions. …”
Publicado 2014
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3112por Shaw, Victoria E, Lane, Brian, Jenkinson, Claire, Cox, Trevor, Greenhalf, William, Halloran, Christopher M, Tang, Joseph, Sutton, Robert, Neoptolemos, John P, Costello, EithneEnlace del recurso
Publicado 2014
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3113“…The model was applied to the pancreatic cancer data. It was shown that, in the populations stratified by gender, race and the geographic area of living, the modeled and observed population hazard rates of pancreatic cancer occurrence have similar turnovers at old ages. …”
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3114Pilot trial of endoscopic ultrasound-guided interstitial chemoradiation of UICC-T4 pancreatic cancer“…BACKGROUND AND AIMS: Both interstitial brachytherapy and interstitial chemotherapy are effective in improving local control in patients with local UICC-T4 pancreatic cancer. In this study, we report the results of endoscopic ultrasound (EUS)-guided interstitial chemoradiation (EUS-ICR) in patients with advanced pancreatic cancer, with respect to tumor response, clinical response, safety, and complications. …”
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3115por Schiavone, Marco, Rampazzo, Elena, Casari, Alessandro, Battilana, Giusy, Persano, Luca, Moro, Enrico, Liu, Shu, Leach, Steve D., Tiso, Natascia, Argenton, Francesco“…To examine in vivo the effects of KRAS(G12D) during pancreatic cancer progression and time correlation with cancer signaling pathway activities, we have generated a zebrafish model of pancreatic adenocarcinoma in which eGFP-KRAS(G12D) expression was specifically driven to the pancreatic tissue by using the GAL4/UAS conditional expression system. …”
Publicado 2014
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3116“…BACKGROUND: Recent global genomic analyses identified 69 gene sets and 12 core signaling pathways genetically altered in pancreatic cancer, which is a highly malignant disease. …”
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3118por Kulkarni, Prajakta S., Haldar, Manas K., Nahire, Rahul R., Katti, Preeya, Ambre, Avinash H., Muhonen, Wallace W., Shabb, John B., Padi, Sathish K. R., Singh, Raushan K., Borowicz, Pawel P., Shrivastava, D. K., Katti, Kalpana S., Reindl, Katie, Guo, Bin, Mallik, SankuEnlace del recurso
Publicado 2014
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3119por Gresham, Gillian K, Wells, George A, Gill, Sharlene, Cameron, Christopher, Jonker, Derek J“…BACKGROUND: Advanced pancreatic cancer confers poor prognosis and treatment advancement has been slow. …”
Publicado 2014
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3120“…Therefore, this study to some extent revealed the molecular basis of TCM ZHENG in pancreatic cancer.…”
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