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  1. 3161
    “…CONCLUSIONS: Specific polymorphisms in the APC and CD24 genes may play a role in pancreatic cancer development. Correlation with survival requires a larger cohort.…”
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    CD24 and APC Genetic Polymorphisms in Pancreatic Cancers as Potential Biomarkers for Clinical Outcome
  2. 3162
    “…Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States and incidence rates are rising. …”
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    Hepatocyte Growth Factor from a Clinical Perspective: A Pancreatic Cancer Challenge
  3. 3163
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    Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer
  4. 3164
    “…Background: Pancreatic cancer, the fifth leading cause of adult cancer death in Western countries, lacks early detection, and displays significant dissemination ability. …”
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    Dual Effects of β(3) Integrin Subunit Expression on Human Pancreatic Cancer Models
  5. 3165
    “…Although there is evidence that non-steroidal anti-inflammatory drugs (NSAIDs) might be able to prevent pancreatic cancer, the findings from epidemiological studies have been inconsistent. …”
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    Aspirin might reduce the incidence of pancreatic cancer: A meta-analysis of observational studies
  6. 3166
    “…BACKGROUND: The tumor microenvironment impacts pancreatic cancer (PC) development, progression and metastasis. …”
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    The inflammatory milieu within the pancreatic cancer microenvironment correlates with clinicopathologic parameters, chemoresistance and survival
  7. 3167
    “…BACKGROUND/AIMS: Pancreatic cancer (PC) is ranked as the fourth leading cause of cancer-related deaths worldwide. …”
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    Fasting cycles potentiate the efficacy of gemcitabine treatment in in vitro and in vivo pancreatic cancer models
  8. 3168
    “…PURPOSE: To identify whether Dickkopf-1 (DKK1) could be a potential biomarker for early detection and prognosis in patients with pancreatic cancer (PC). METHODS: Serum was collected from 140 patients with pancreatic adenocarcinoma and 92 control patients without pancreatic adenocarcinoma. …”
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    Serum dickkopf-1 is a novel serological biomarker for the diagnosis and prognosis of pancreatic cancer
  9. 3169
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    The 3+3 versus model-based approach: implementation in the CAPCISUM pancreatic cancer trial
  10. 3170
    “…It is also frequently prescribed to diabetic pancreatic cancer patients and has been shown to associate with a better outcome. …”
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    Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages
  11. 3171
    “…ABO blood type has previously been identified as a risk factor for thrombosis and pancreatic cancer (PC). The aim of the study is to demonstrate the associations between ABO blood type and other clinical factors with the risk of thromboembolism (TE) in patients with PC. …”
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    ABO non-O type as a risk factor for thrombosis in patients with pancreatic cancer
  12. 3172
    “…Also, multidrug resistance (MDR) is generally associated with tumor chemoresistance in pancreatic cancer. However, the correlation between TM4SF1 and MDR remains unknown. …”
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    TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo
  13. 3173
    “…This novel siRNA based drug was studied, in combination with chemotherapy, as targeted therapy for Locally Advanced Pancreatic Cancer (LAPC). METHODS: An open-label Phase 1/2a study in the first-line setting of patients with non-operable LAPC was initiated. …”
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    RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients
  14. 3174
    “…Thus, we carried out a meta-analysis evaluating the relationship between SPARC expression and the prognosis of patients with pancreatic cancer. METHODS: We searched PubMed, EMBASE and Web of Science for relevant articles. …”
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    Prognostic Value of SPARC in Patients with Pancreatic Cancer: A Systematic Review and Meta-Analysis
  15. 3175
    “…BACKGROUND: The surveillance of subjects at risk of pancreatic cancer is restricted to clinical research; the incidence of familial pancreatic cancer needs to be better established. …”
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    Implications and issues related to familial pancreatic cancer: a cohort study of hospitalized patients
  16. 3176
    “…Pancreatic cancer is one of most aggressive forms of cancer. …”
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    The Clinical Significance of Phosphorylated Heat Shock Protein 27 (HSPB1) in Pancreatic Cancer
  17. 3177
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    Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer
  18. 3178
    “…A two-stage case-control study was conducted to examine the association between six candidate U2-depedent spliceosome genes (SRSF1, SRSF2, SF3A1, SF3B1, SF1 and PRPF40B) and pancreatic cancer (PC). Subjects with one or two T alleles at rs2074733 in SF3A1 had a lower risk of PC compared to those with two C alleles in combined two populations (OR: 0.59, 95% confidence interval: 0.48–0.73, False discovery rate (FDR)-P = 1.5E-05). …”
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    SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer
  19. 3179
    “…However, little is known about their value as biomarkers in pancreatic cancer (PC). We applied an Arraystar Human LncRNA Microarray which targeting 7419 lncRNAs to determine the lncRNA expression profile in PC and to screen the potential biomarkers. …”
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    Expression profile of long non-coding RNAs in pancreatic cancer and their clinical significance as biomarkers
  20. 3180
    “…TAZ thus may be a target for effective therapeutic strategies for pancreatic cancer.…”
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    Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progression
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