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  1. 3181
    “…In the present studies we evaluated an anti-cancer natural product silibinin for its effectiveness in targeting pancreatic cancer aggressiveness and the cachectic properties of pancreatic cancer cells and tumors. …”
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    Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth
  2. 3182
    “…We found that tumorspheres derived from pancreatic cancer cell line Panc-1 possessed self-renewal, differentiation and stemness properties. …”
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    Hedgehog Signaling Regulates Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem-Like Cells
  3. 3183
    “…Similar to results previously reported in the literature, this analysis did not identify a significant association between BSC of 25(OH)D and OS or TTP in patients with pancreatic cancer.…”
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    Retrospective analysis of the influence of 25-hydroxyvitamin D on disease progression and survival in pancreatic cancer
  4. 3184
    “…In this study, we demonstrate that Cep70 is highly expressed in pancreatic cancer tissues. Cep70 expression correlates with clinicopathological parameters of pancreatic cancer, including histological grade, pathological tumor node metastasis stage, lymph node metastasis, and carbohydrate antigen 19-9 level. …”
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    Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization
  5. 3185
    “…Adult patients with biliary tract or pancreatic cancer were divided into three groups according to whether they had mild, moderate, or severe liver dysfunction, evaluated on the basis of serum bilirubin and liver transaminase levels at baseline. …”
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    Optimal dose of gemcitabine for the treatment of biliary tract or pancreatic cancer in patients with liver dysfunction
  6. 3186
    “…In that regard, we have previously demonstrated a role of gemcitabine-induced CXCR4 signaling as a counter-defense mechanism, which also promoted invasiveness of pancreatic cancer (PC) cells. Here, we investigated the effect of gemcitabine on endothelial cell phenotype. …”
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    Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications
  7. 3187
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    Subclinical Inflammation and Endothelial Dysfunction in Patients with Chronic Pancreatitis and Newly Diagnosed Pancreatic Cancer
  8. 3188
    “…Concomitantly targeting the TGF-β type I receptor (TβRI) kinase with SB505124 and JAK1-2 with ruxolitinib suppresses JAK1 phosphorylation and blocks proliferative cross-talk between human pancreatic cancer cells (PCCs) and human endothelial cells (ECs), and these anti-proliferative effects were mimicked by JAK1 silencing in ECs. …”
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    Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes
  9. 3189
    “…To further understand how thyroid hormone affects pancreatic cancer behavior, functional studies including wound-induced cell migration, proliferation, and invasion were performed on pancreatic cancer cell lines, MiaPaCa-2 and AsPC-1. …”
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    Hypothyroidism in Pancreatic Cancer: Role of Exogenous Thyroid Hormone in Tumor Invasion—Preliminary Observations
  10. 3190
    “…Pain management in pancreatic cancer consists mainly of pharmacological treatment according to the WHO analgesic ladder. …”
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    Invasive treatment of pain associated with pancreatic cancer on different levels of WHO analgesic ladder
  11. 3191
    Publicado 2016
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    CT Imaging Biomarkers Predict Clinical Outcomes After Pancreatic Cancer Surgery: Erratum
  12. 3192
    “…AIF expression was then suppressed in a panel of five pancreatic cancer cell lines that display diverse metabolic phenotypes. …”
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    Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells
  13. 3193
    “…CONCLUSIONS: It was observed that the CAD system developed in the study performed better in diagnosing pancreatic cancer images based on classification by patient age compared to diagnosis without classification. …”
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    Age-based computer-aided diagnosis approach for pancreatic cancer on endoscopic ultrasound images
  14. 3194
    por Rajamani, Deepa, Bhasin, Manoj K.
    Publicado 2016
    “…BACKGROUND: Pancreatic cancer is an aggressive cancer with dismal prognosis, urgently necessitating better biomarkers to improve therapeutic options and early diagnosis. …”
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    Identification of key regulators of pancreatic cancer progression through multidimensional systems-level analysis
  15. 3195
    “…CONCLUSIONS: Transpapillary forceps biopsy of biliary strictures after sphincterotomy for tissue sampling is safe and a significantly higher sensitive method in cholangiocarcinoma but not in pancreatic cancer.…”
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    Transpapillary biliary biopsy for malignant biliary strictures: comparison between cholangiocarcinoma and pancreatic cancer
  16. 3196
    “…Chemoresistance is the major impediment for treating pancreatic cancer. Herb-derived compound triptolide (TP) can inhibit proliferation of chemo-resistant pancreatic cancer (CPC) cell lines through multiple mechanisms, which exhibited superior anticancer efficacy compared with gemcitabine. …”
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    Toward targeted therapy in chemotherapy-resistant pancreatic cancer with a smart triptolide nanomedicine
  17. 3197
    “…Pancreatic cancer reveals the worst prognosis among human cancers with little improvement in its clinical outcome in the last three decades. …”
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    Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown()
  18. 3198
    “…In an orthotopic pancreatic cancer mouse model, both low and high dose verapamil was shown to substantially reduce L3.6pl(Gres)-SP cell tumor growth and metastasis, enhance tumor apoptosis, and reduce microvascular density.…”
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    Verapamil inhibits tumor progression of chemotherapy-resistant pancreatic cancer side population cells
  19. 3199
    por Hagopian, Moriah M, Brekken, Rolf A
    Publicado 2014
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    Stromal TGFβR2 signaling: a gateway to progression for pancreatic cancer
  20. 3200
    “…Our results indicated that down-regulation of CIP2A could be a novel therapeutic strategy for pancreatic cancer.…”
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    CIP2A down regulation enhances the sensitivity of pancreatic cancer cells to gemcitabine
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