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3221“…Pancreatic cancer has a rather dismal prognosis mainly due to high malignance of tumor biology. …”
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3222por Buanes, Trond A“…Chemotherapy with improved effect in patients with metastatic pancreatic cancer has recently been established, launching a new era for patients with this very aggressive disease. …”
Publicado 2016
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3223“…Pancreatic cancer is one of the deadliest cancers worldwide, and life expectancy after diagnosis is often short. …”
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3224por Kohi, Shiro, Sato, Norihiro, Koga, Atsuhiro, Hirata, Keiji, Harunari, Enjuro, Igarashi, YasuhiroEnlace del recurso
Publicado 2016
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3225por Muralidharan-Chari, Vandhana, Kohan, Hamed Gilzad, Asimakopoulos, Alexandros G., Sudha, Thangirala, Sell, Stewart, Kannan, Kurunthachalam, Boroujerdi, Mehdi, Davis, Paul J., Mousa, Shaker A.“…High mortality in pancreatic cancer patients is partly due to resistance to chemotherapy. …”
Publicado 2016
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3226“…BACKGROUND: Pancreatic cancer (PC) remains difficult to treat, despite the recent advances in various anticancer therapies. …”
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3227“…We aimed to uncover transcription factors that regulate the transcriptional response of oncogenic KRAS in pancreatic cancer and to understand their clinical relevance. …”
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3228por Lee, Sung Hwan, Kang, Chang Moo, Kim, Hogeun, Hwang, Ho Kyoung, Song, Si Young, Seong, Jinsil, Kim, Myoung Jin, Lee, Woo Jung“…Among 86 patients with pancreatic cancer who underwent radical pancreatectomy following NeoCRT, 10 patients (11.6%) were reported to pCR. …”
Publicado 2015
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3229por Min, Eun-Ki, Chong, Jae Uk, Hwang, Ho Kyoung, Pae, Sang Joon, Kang, Chang Moo, Lee, Woo Jung“…Poor patients’ perceived pain control was revealed as an independent risk factor of both DFS (HR = 4.157; 95%CI: 1.938-8.915; P < 0.001) and OS (HR = 4.741; 95%CI: 2.214-10.153; P < 0.001) in resected left-sided pancreatic cancer. CONCLUSION: Adequate postoperative pain relief during the early postoperative period has important clinical implications for oncologic outcomes after resection of left-sided pancreatic cancer.…”
Publicado 2017
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3230“…Since SATB2 is highly expressed in human pancreatic cancer tissues and cell lines, but not in HPNE cells and normal pancreatic tissue, it can drive pancreatic cancer growth and metastasis. …”
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3231por Jung, Jaeyun, Lee, Cue Hyunkyu, Seol, Hyang Sook, Choi, Yeon Sook, Kim, Eunji, Lee, Eun Ji, Rhee, Je-Keun, Singh, Shree Ram, Jun, Eun Sung, Han, Buhm, Hong, Seung Mo, Kim, Song Cheol, Chang, SuhwanEnlace del recurso
Publicado 2016
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3232por King, Helen, Thillai, Kiruthikah, Whale, Andrew, Arumugam, Prabhu, Eldaly, Hesham, Kocher, Hemant M., Wells, Claire M.“…However, the functionality of PAK4 in pancreatic cancer and the contribution made by HGF signalling to pancreatic cancer cell motility remain to be elucidated. …”
Publicado 2017
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3233“…This article summarizes the current preclinical and clinical status of panobinostat in pancreatic cancer. Preclinical data suggests that panobinostat has potential inhibitory activity in pancreatic cancer cells by targeting various pathways and factors involved in the development of cancer. …”
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3234“…Furthermore, forced Par-4 expression can sensitize pancreatic cancer cells to cisplatin. Finally, we demonstrate that TRIM21 expression predicts survival in pancreatic cancer patients. …”
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3235“…AIM: To examine the role of microRNA 1181 (miR-1181) in invasion and proliferation in pancreatic cancer. METHODS: We analyzed the expression of miR-1181 in several pancreatic cancer cell lines and generated stable MIA-PaCa-2 and PANC-1 cell lines with up-regulated miR-1181 expression using an adenovirus delivery system. …”
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3236por Au, Minnie, Emeto, Theophilus I., Power, Jacinta, Vangaveti, Venkat N., Lai, Hock C.“…Pancreatic cancer is an aggressive disease with a five year survival rate of less than 5%, which is associated with late presentation. …”
Publicado 2016
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3237por Frouws, Martine A., Mulder, Babs G. Sibinga, Bastiaannet, Esther, Zanders, Marjolein M.J., van Herk-Sukel, Myrthe P.P., de Leede, Eleonora M., Bonsing, Bert A., Mieog, J. Sven. D., Van de Velde, Cornelis J.H., Liefers, Gerrit-Jan“…The aim of the study was to assess the association between overall survival, pancreatic cancer, and metformin use. A retrospective cohort study of 1111 patients with pancreatic cancer was conducted using data from The Netherlands Comprehensive Cancer Organization (1998–2011). …”
Publicado 2017
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3238por Molina-Montes, Esther, Sánchez, María-José, Buckland, Genevieve, Bueno-de-Mesquita, H B(as), Weiderpass, Elisabete, Amiano, Pilar, Wark, Petra A, Kühn, Tilman, Katzke, Verena, Huerta, José María, Ardanaz, Eva, Quirós, José Ramón, Affret, Aurélie, His, Mathilde, Boutron-Ruault, Marie-Christine, Peeters, Petra H, Ye, Weimin, Sund, Malin, Boeing, Heiner, Iqbal, Khalid, Ohlsson, Bodil, Sonestedt, Emily, Tjønneland, Anne, Petersen, Kristina EN, Travis, Ruth C, Skeie, Guri, Agnoli, Claudia, Panico, Salvatore, Palli, Domenico, Tumino, Rosario, Sacerdote, Carlotta, Freisling, Heinz, Huybrechts, Inge, Overvad, Kim, Trichopoulou, Antonia, Bamia, Christina, Vasilopoulou, Effie, Wareham, Nick, Khaw, Kay-Tee, Cross, Amanda J, Ward, Heather A, Riboli, Elio, Duell, Eric J“…BACKGROUND: The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. …”
Publicado 2017
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3239Ribosomal protein L34 promotes the proliferation, invasion and metastasis of pancreatic cancer cellspor Wei, Feng, Ding, Lijuan, Wei, Zhentong, Zhang, Yandong, Li, Yang, Qinghua, Luo, Ma, Yuteng, Guo, Liang, Lv, Guoyue, Liu, Yan“…However, the expression status and function of RPL34 in pancreatic cancer (PC) remains unclear. In this study, we find that RPL34 is overexpressed in PC tissues and cell lines, which is correlated with decreased methylation of its promoter. …”
Publicado 2016
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3240“…We investigated the coordinate function of Musashi2-Numb in the development of pancreatic cancer (PC) in vitro and vivo. Both Musashi2 protein and mRNA levels were higher in PC tissues than that in paired normal pancreas (P<0.05). …”
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