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321por Beg, Muhammad Shaalan, Dwivedi, Alok Kumar, Ahmad, Syed Arif, Ali, Sadia, Olowokure, Olugbenga“…INTRODUCTION: Diabetes mellitus (DM) has the potential to impact the pathogenesis, treatment, and outcome of pancreatic cancer. This study evaluates the impact of DM on pancreatic cancer survival. …”
Publicado 2014
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322“…In addition, traditional chemotherapy does not show ideal results because pancreatic cancer (PC) exhibits hypovascular characteristics. …”
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323por Bittoni, Alessandro, Santoni, Matteo, Lanese, Andrea, Pellei, Chiara, Andrikou, Kalliopi, Stefano, Cascinu“…In recent years, increasing evidences support the use of neoadjuvant strategies in pancreatic cancer in patients with resectable pancreatic cancer as well as in patients with borderline resectable or locally advanced PDAC in order to allow early treatment of micrometastatic disease, tumour regression, and reduced risk of peritoneal tumour implantation during surgery. …”
Publicado 2014
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324“…A single Phase II study has evaluated combination therapy with ixabepilone in the management of patients with pancreatic cancer, pairing it with cetuximab with clinical benefit. …”
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325“…Here we will review the current understanding of the biology and the pro-tumourigenic functions of TAMs in cancer and specifically in PDA, and highlight potential therapeutic strategies to target TAMs and to improve current therapies for pancreatic cancer. [BMB Reports 2013; 46(3): 131-138]…”
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326por Morran, Douglas C, Wu, Jianmin, Jamieson, Nigel B, Mrowinska, Agata, Kalna, Gabriela, Karim, Saadia A, Au, Amy Y M, Scarlett, Christopher J, Chang, David K, Pajak, Malgorzata Z, Oien, Karin A, McKay, Colin J, Carter, C Ross, Gillen, Gerry, Champion, Sue, Pimlott, Sally L, Anderson, Kurt I, Evans, T R Jeffry, Grimmond, Sean M, Biankin, Andrew V, Sansom, Owen J, Morton, Jennifer P“…OBJECTIVE: Pancreatic cancer is a leading cause of cancer-related death in the Western world. …”
Publicado 2014
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327“…Pancreatic cancer is one of the most aggressive, drug-resistant and lethal types of cancer with poor prognosis. …”
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328
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329por Xie, Guoxiang, Lu, Lingeng, Qiu, Yunping, Ni, Quanxing, Zhang, Wei, Gao, Yu-Tang, Risch, Harvey A., Yu, Herbert, Jia, Wei“…[Image: see text] Patients with pancreatic cancer (PC) are usually diagnosed at late stages, when the disease is nearly incurable. …”
Publicado 2014
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330por Wei, Dongping, Zhang, Qiang, Schreiber, Jason S., Parsels, Leslie A., Abulwerdi, Fardokht A., Kausar, Tasneem, Lawrence, Theodore S., Sun, Yi, Nikolovska-Coleska, Zaneta, Morgan, Meredith A.“…In order to identify targets whose inhibition may enhance the efficacy of chemoradiation in pancreatic cancer, we previously conducted an RNAi library screen of 8,800 genes. …”
Publicado 2015
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331“…The correlation between hypoxia and pancreatic cancer has long been discussed. Hao’s research team made many efforts on revealing the oncogenic function of hypoxic inducible factor-1 (HIF-1) in pancreatic cancer progression and development in recent years. …”
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332“…BACKGROUND: Pancreatic cancer (PancCa) is recognized as a component of many well-described hereditary cancer syndromes. …”
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333por Dong, He, Qian, Dongmeng, Wang, Yaqiu, Meng, Lingsheng, Chen, Dong, Ji, Xiangyu, Feng, Wei“…However, to our knowledge, there has been no study to characterize its usefulness as a serum marker for human pancreatic cancer. Furthermore, the relation between survivin expression and the serum level of survivin has not been widely studied in PDAC. …”
Publicado 2015
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334
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335por Humeau, Marine, Vignolle-Vidoni, Alix, Sicard, Flavie, Martins, Frédéric, Bournet, Barbara, Buscail, Louis, Torrisani, Jérôme, Cordelier, Pierre“…BACKGROUND: Pancreatic cancer is the fourth leading cause of cancer death in Western countries, with the lowest 1-year survival rate among commonly diagnosed cancers. …”
Publicado 2015
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336por Fulda, Simone“…Resistance to apoptosis (programmed cell death) is a characteristic feature of human malignancies including pancreatic cancer, which is one of the leading causes of cancer deaths in the western world. …”
Publicado 2009
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337
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338por Min, Young Joo, Joo, Kwang Ro, Park, Neung Hwa, Yun, Tae Kwon, Nah, Yang Won, Nam, Chang Woo, Park, Jae Hoo“…BACKGROUND: Advanced, unresectable pancreatic cancer is an extremely aggressive disease. The 5-year survival rate for pancreatic cancer is only less than 5%. …”
Publicado 2002
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339por Torres, Carolina, Linares, Ana, Alejandre, Maria José, Palomino-Morales, Rogelio J., Caba, Octavio, Prados, Jose, Aránega, Antonia, Delgado, Juan R., Irigoyen, Antonio, Martínez-Galán, Joaquina, Ortuño, Francisco M., Rojas, Ignacio, Perales, Sonia“…The multivariate model showed a better performance and it could represent a novel panel of serum cytokines that correlates to poor prognosis in pancreatic cancer. B7-1/CD80, EG-VEGF/PK1, IL-29, NRG1-beta1/HRG1-beta1, and PD-ECGF expressions portend a poor prognosis for patients with pancreatic cancer and these cytokines could represent novel therapeutic targets for this disease.…”
Publicado 2015
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340por Noguchi, Kozo, Eguchi, Hidetoshi, Konno, Masamitsu, Kawamoto, Koichi, Nishida, Naohiro, Koseki, Jun, Wada, Hiroshi, Marubashi, Shigeru, Nagano, Hiroaki, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi“…Here we examined the susceptibility of pancreatic cancer stem cells (CSC) and non-CSC to reprogramming. …”
Publicado 2015
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