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3421por Jang, Eunseo, Son, Minhee, Jang, Junhee, Lee, In-Hyun, Kim, Sol, Kwon, Taejun, Jeon, Yong-hyun, Koh, Woo-Suk, Kim, Kil-Soo, Kim, Sang Kyoon“…Moreover, to evaluate the antitumor effect of DHP23002 in pancreatic cancer treatment, the drug was administered to female athymic nude mice at 0 (vehicle), 25, 62.5, and 125 mg/kg on alternate days; the efficacy of the agent was compared with the efficacy of intravenous Taxol(®) injections at 10 mg/kg once per week. …”
Publicado 2019
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3422por Sun, Qiqing, Zhang, Yiyin, Liu, Mengqi, Ye, Zeng, Yu, Xianjun, Xu, Xiaowu, Qin, Yi“…Although many studies have concentrated on the role of galectins in pancreatic cancer, the results remain controversial. Hence, we performed a comprehensive meta-analysis to clarify the precise diagnostic and prognostic value of galectins in pancreatic cancer. …”
Publicado 2019
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3423por Bhagat, Tushar D, Von Ahrens, Dagny, Dawlaty, Meelad, Zou, Yiyu, Baddour, Joelle, Achreja, Abhinav, Zhao, Hongyun, Yang, Lifeng, Patel, Brijesh, Kwak, Changsoo, Choudhary, Gaurav S, Gordon-Mitchell, Shanisha, Aluri, Srinivas, Bhattacharyya, Sanchari, Sahu, Srabani, Bhagat, Prafulla, Yu, Yiting, Bartenstein, Matthias, Giricz, Orsi, Suzuki, Masako, Sohal, Davendra, Gupta, Sonal, Guerrero, Paola A, Batra, Surinder, Goggins, Michael, Steidl, Ulrich, Greally, John, Agarwal, Beamon, Pradhan, Kith, Banerjee, Debabrata, Nagrath, Deepak, Maitra, Anirban, Verma, AmitEnlace del recurso
Publicado 2019
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3424“…Pancreatic cancer is a lethal disease, and resistance to chemotherapy is a critical factor influencing the postoperative prognosis. …”
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3425por Archibugi, Livia, Testoni, Sabrina Gloria Giulia, Redegalli, Miriam, Petrone, Maria Chiara, Reni, Michele, Falconi, Massimo, Doglioni, Claudio, Capurso, Gabriele, Arcidiacono, Paolo GiorgioEnlace del recurso
Publicado 2019
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3426“…BACKGROUND: There is no standard therapy for second-line treatment of gemcitabine-refractory pancreatic cancer patients with poor performance status. …”
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3427por Lee, Ji Hyeon, Cho, Young-ra, Kim, Ji Hye, Kim, Jongwook, Nam, Hae Yun, Kim, Seong Who, Son, Jaekyoung“…Overall, our findings show that the BCAA metabolic pathway may provide a novel therapeutic target for pancreatic cancer.…”
Publicado 2019
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3428por Kanno, Yoshihide, Koshita, Shinsuke, Ogawa, Takahisa, Kusunose, Hiroaki, Masu, Kaori, Sakai, Toshitaka, Yonamine, Keisuke, Kawakami, Yujiro, Fujii, Yuki, Miyamoto, Kazuaki, Murabayashi, Toji, Kozakai, Fumisato, Horaguchi, Jun, Noda, Yutaka, Oikawa, Masaya, Okada, Takaho, Ito, Kei“…The final diagnosis of the MPD stenosis was judged to be pancreatic cancer in 9 patients (47%), including 3 with intraepithelial cancer, and to be a non-neoplastic change in 10. …”
Publicado 2019
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3429por Grapa, Cristiana Maria, Mocan, Teodora, Gonciar, Diana, Zdrehus, Claudiu, Mosteanu, Ofelia, Pop, Teodora, Mocan, Lucian“…Studies show that overexpressed epidermal growth factor receptor (EGFR) is a common occurrence, linking this to the progression of pancreatic cancer, although the association between its expression and the survival rate is rather controversial. …”
Publicado 2019
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3430“…In recent years, it has been found that IncRNA HULC is increasingly expressed in pancreatic cancer tissues and is involved in the development and progression of pancreatic cancer. …”
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3431“…However, its role in pancreatic cancer has seldom been investigated. In this report, we provide evidence that RAD51, regulated by KRAS, promotes pancreatic cancer cell proliferation. …”
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3432“…BACKGROUND: Small molecular inhibitors such as gefitinib (Gefi), which target EGF receptor (EGFR), are considered to be a viable pathway for the selective inhibition of pancreatic cancer (PC) development. However, the large difference in Gefi response between PC patient individuals and PC cell lines severely limits the clinical efficacy of Gefi. …”
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3433por Gonoi, Wataru, Okuma, Hidemi, Hayashi, Takana Y., Akahane, Masaaki, Nakai, Yousuke, Tateishi, Ryosuke, Mizuno, Suguru, Suzuki, Yuichi, Mitsuda, Minoru, Matsuda, Kanako, Nakagawa, Keiichi, Isayama, Hiroyuki, Miyagawa, Kiyoshi, Koike, Kazuhiko, Abe, Osamu“…BACKGROUND/AIMS: We aimed to investigate incidence, characteristics, and possible risk factors of pancreatic cancer in patients under observation for hepatocellular carcinoma (HCC) because the association of hepatitis virus B infection and pancreatic cancer has been reported. …”
Publicado 2019
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3434por Takahashi, Kenji, Ota, Yu, Kogure, Takayuki, Suzuki, Yuko, Iwamoto, Hidetaka, Yamakita, Keisuke, Kitano, Yohei, Fujii, Satoshi, Haneda, Masakazu, Patel, Tushar, Ota, TsuguhitoEnlace del recurso
Publicado 2019
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3435por Sugimori, Makoto, Sugimori, Kazuya, Tsuchiya, Hiromi, Suzuki, Yoshimasa, Tsuyuki, Sho, Kaneta, Yoshihiro, Hirotani, Akane, Sanga, Katsuyuki, Tozuka, Yuichiro, Komiyama, Satoshi, Sato, Takeshi, Tezuka, Shun, Goda, Yoshihiro, Irie, Kuniyasu, Miwa, Haruo, Miura, Yuuki, Ishii, Tomohiro, Kaneko, Takashi, Nagahama, Masatsugu, Shibata, Wataru, Nozaki, Akito, Maeda, ShinEnlace del recurso
Publicado 2019
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3436por Yan, Ying, Hein, Ashley L., Etekpo, Asserewou, Burchett, Katrina M., Lin, Chi, Enke, Charles A., Batra, Surinder K., Cowan, Kenneth H., Ouellette, Michel M.Enlace del recurso
Publicado 2020
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3437“…Given that the biological processes governing the oncogenesis of pancreatic cancers could present useful therapeutic targets, there is a pressing need to molecularly distinguish between different clinically relevant pancreatic cancer subtypes. …”
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3438por Wu, Lili, Zhou, Yuhong, Fan, Yue, Rao, Shengxiang, Ji, Yuan, Sun, Jing, Li, Tingting, Du, Shisuo, Guo, Xi, Zeng, Zhaochong, Lou, Wenhui“…Object: To evaluate the efficacy and tolerability of consolidative chemoradiotherapy (cCRT) after induced chemotherapy (iCT) for locally advanced pancreatic cancer (LAPC). Patients and methods: Patients with LAPC were enrolled from January 2013 to November 2018. …”
Publicado 2020
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3439por Ando, Yohei, Ohuchida, Kenoki, Otsubo, Yoshiki, Kibe, Shin, Takesue, Shin, Abe, Toshiya, Iwamoto, Chika, Shindo, Koji, Moriyama, Taiki, Nakata, Kohei, Miyasaka, Yoshihiro, Ohtsuka, Takao, Oda, Yoshinao, Nakamura, Masafumi“…Here, we investigate the significance of necroptosis in pancreatic cancer. METHODS: We used immunohistochemistry and western blot analysis to evaluate expression of the key mediators of necroptosis—receptor-interacting serine/threonine protein kinase 3 (RIP3) and mixed lineage kinase domain-like (MLKL)—in human pancreatic cancer. …”
Publicado 2020
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