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  1. 3841
    “…When we transduced pancreatic cancers with sgRNAs that targeted 2–16 target sites in the human genome, we found that increasing the number of CRISPR-Cas9 target sites produced greater cytotoxicity, with >99% growth inhibition observed by targeting only 12 sites. …”
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    Mechanism of delayed cell death following simultaneous CRISPR-Cas9 targeting in pancreatic cancers
  2. 3842
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    Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness
  3. 3843
    “…Our study aimed to illustrate the effect of M2 macrophages in pancreatic cancer (PC). Materials and Methods: The open-access data used for analysis were downloaded from The Cancer Genome Atlas Program database, as well as some online databases. …”
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    Comprehensive Investigation Illustrates the Role of M2 Macrophages and Its Related Genes in Pancreatic Cancer
  4. 3844
    “…Patients with metastatic pancreatic cancer have limited treatment options and a dismal prognosis. …”
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    RET rearrangement-positive pancreatic cancer has remarkable response to pralsetinib: a case report
  5. 3845
    “…Additionally, CAFs with high glycolytic activity contributed to pancreatic cancer cell migration, and blocking CAF glycolysis reversed this process, suggesting that glycolytic CAFs promote malignant biological behavior in pancreatic cancer. …”
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    Metabolic reprogramming of cancer-associated fibroblasts in pancreatic cancer contributes to the intratumor heterogeneity of PET-CT
  6. 3846
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    Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer
  7. 3847
    “…Introduction Pancreatic cancer resections comprise a class of complex surgical operations with a high postoperative morbidity rate. …”
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    Exploring the Surgical Outcomes of Pancreatic Cancer Resections Performed in Low- Versus High-Volume Centers
  8. 3848
    por Liou, Geou-Yarh, Byrd, Crystal J.
    Publicado 2023
    “…SIMPLE SUMMARY: Among all types of pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC) is the most common type and has an extremely low survival rate. …”
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    Diagnostic Bioliquid Markers for Pancreatic Cancer: What We Have vs. What We Need
  9. 3849
    “…The incidences of pancreatic cancer (PanCa) are sharply rising, and it will become the second leading cause of cancer related deaths by 2030. …”
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    Integrative big transcriptomics data analysis implicates crucial role of MUC13 in pancreatic cancer
  10. 3850
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    The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer
  11. 3851
    “…BACKGROUND: Special subtypes of pancreatic cancer, such as acinar cell carcinoma (ACC), adenosquamous carcinoma (ASC), and anaplastic carcinoma of the pancreas (ACP), are rare, and so data on them are limited. …”
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    Genomic landscape and clinical features of rare subtypes of pancreatic cancer: analysis with the national database of Japan
  12. 3852
    “…Dietary factors may be associated with the occurrence of pancreatic cancer. This umbrella review aimed to review and grade the evidence for the associations between dietary factors and pancreatic cancer risk. …”
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    Dietary Factors and Pancreatic Cancer Risk: An Umbrella Review of Meta-Analyses of Prospective Observational Studies
  13. 3853
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    Editorial Expression of Concern: Response of human pancreatic cancer cell xenografts to tetraiodothyroacetic acid nanoparticles
  14. 3854
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    Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer
  15. 3855
    “…OBJECTIVE: At present, pancreatic cancer (PC) has a high morbidity and mortality rate and a poor prognosis. …”
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    Efficacy and safety of apatinib combined with radiotherapy in the treatment of advanced pancreatic cancer: a meta-analysis
  16. 3856
    por Poh, Ashleigh R., Ernst, Matthias
    Publicado 2023
    “…We also provide a comprehensive update of SRC inhibitors in the clinic, and discuss the clinical challenges associated with targeting SRC in pancreatic cancer.…”
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    Functional roles of SRC signaling in pancreatic cancer: Recent insights provide novel therapeutic opportunities
  17. 3857
    “…Of the 33 patients with advanced pancreatic cancer, 9 received CDI, 20 received HECDI, and 4 (control group) received placebo. …”
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    Awaken Immune Cells by Hapten Enhanced Intratumoral Chemotherapy with Penicillin Prolong Pancreatic Cancer Survival
  18. 3858
    “…We measured the impact of ANGPTL4 overexpression in a common pancreatic cancer cell line, MIA PaCa-2 cells, using CRISPRa for overexpression and DsiRNA for knockdown. …”
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    Transcriptomic and functional analysis of ANGPTL4 overexpression in pancreatic cancer nominates targets that reverse chemoresistance
  19. 3859
    “…SIMPLE SUMMARY: Pancreatic cancer is a devastating disease with more than 60,000 new cases each year and a less than 10 percent 3-year overall survival rate. …”
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    deepPERFECT: Novel Deep Learning CT Synthesis Method for Expeditious Pancreatic Cancer Radiotherapy
  20. 3860
    “…Consequently, identifying mutational profiles and molecular biomarkers is essential for increasing the viability of precision therapy for pancreatic cancer. METHODS: We collected blood and tumor tissue samples from 47 Chinese pancreatic cancer patients and used whole-exome sequencing (WES) to evaluate the genetic landscape. …”
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    Clinical and genetic characteristics in pancreatic cancer from Chinese patients revealed by whole exome sequencing
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