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21por Krishnamoorthy, Mithunah, Lenehan, John G., Burton, Jeremy P., Maleki Vareki, Saman“…SIMPLE SUMMARY: Pancreatic cancer is an aggressive disease that has few options for treatment. …”
Publicado 2020
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23“…Pancreatic cancer evades immunologic elimination by a variety of mechanisms, including induction of an immunosuppressive microenvironment. …”
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24“…Pancreatic cancer is associated with both family and hereditary cancer syndromes. …”
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26por Wu, Lin-Wen, Zhang, Jian-Kang, Rao, Mingjun, Zhang, Zuo-Yan, Zhu, Hua-Jian, Zhang, Chong“…RESULTS: Our data showed that harmine exerted an anti-proliferative effect and cell cycle arrest at G2/M in pancreatic cancer cells. Meanwhile, harmine plus gemcitabine showed strong synergy in inhibiting the proliferation of pancreatic cancer cells. …”
Publicado 2019
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27por Zhang, Yue-Feng, Zhou, Yi-Zhao, Zhang, Bo, Huang, Shi-Fei, Li, Peng-Ping, He, Xiao-Man, Cao, Guo-Dong, Kang, Mu-Xing, Dong, Xin, Wu, Yu-Lian“…The results showed that pancreatic cancer cell-derived exosomes (Exo-Pan and Exo-Mia) promoted the pancreatic cancer recruitment of PSCs. …”
Publicado 2019
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28por Norton, Jeffrey, Foster, Deshka, Chinta, Malini, Titan, Ashley, Longaker, Michael“…Pancreatic cancer is the 4th leading cause of cancer deaths in the United States. …”
Publicado 2020
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29por Kiriukova, Mariia, de la Iglesia Garcia, Daniel, Panic, Nikola, Bozhychko, Maryana, Avci, Bartu, Maisonneuve, Patrick, de-Madaria, Enrique, Capurso, Gabriele, Sandru, Vasile“…Aims: The aim of this study is to assess the impact of nutritional status, pancreatic exocrine insufficiency (PEI), and other clinical factors on patient outcomes in patients with advanced PDAC. Methods: PAncreatic Cancer MAlnutrition and Pancreatic Exocrine INsufficiency in the Course of Chemotherapy in Unresectable Pancreatic Cancer (PAC-MAIN) is an international multicenter prospective observational cohort study. …”
Publicado 2020
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30por Tu, Jihao, Huang, Zhehao, Wang, Yin, Wang, Meijing, Yin, Zukun, Mei, Xianglin, Li, Meiying, Li, Lisha“…In this paper, we analyzed the transcriptome profiles from the human normal pancreas, pancreatitis, pancreatic cancer and metastatic pancreatic cancer to study the intricate associations among pancreatic cancer progression. …”
Publicado 2021
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31por Palzer, Julian, Mues, Benedikt, Goerg, Richard, Aberle, Merel, Rensen, Sander S, Olde Damink, Steven W M, Vaes, Rianne D W, Cramer, Thorsten, Schmitz-Rode, Thomas, Neumann, Ulf P, Slabu, Ioana, Roeth, Anjali A“…CONCLUSION: Treatment with MFH strongly diminished pancreatic cancer cell viability in vitro, making it a promising treatment strategy. …”
Publicado 2021
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32por Kasuga, Akiyoshi, Okamoto, Takeshi, Udagawa, Shohei, Mori, Chinatsu, Mie, Takafumi, Furukawa, Takaaki, Yamada, Yuto, Takeda, Tsuyoshi, Matsuyama, Masato, Sasaki, Takashi, Ozaka, Masato, Ueki, Arisa, Sasahira, Naoki“…Hereditary pancreatic cancers are caused by several inherited genes. …”
Publicado 2022
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33por Ma, Dong-Mei, Dong, Xiao-Wu, Han, Xiao, Ling, Zhi, Lu, Guo-Tao, Sun, Yun-Yun, Yin, Xu-Dong“…Methods: From the 500 thousand population cohort of UKB, according to the age and gender of patients with pancreatic cancer 1:10, matching the control without pancreatic cancer, the binary Logistic regression model was used to analyze the relationship between pancreatitis and pancreatic cancer, and subgroup analyses were used to identify potential effect modifiers. …”
Publicado 2023
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34“…Pancreatic cancer is a high mortality malignancy with almost equal mortality and morbidity rates. …”
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35por Papa, Valerio, Schepis, Tommaso, Coppola, Gaetano, Chiappetta, Michele Francesco, Del Vecchio, Livio Enrico, Rozera, Tommaso, Quero, Giuseppe, Gasbarrini, Antonio, Alfieri, Sergio, Papa, Alfredo“…SIMPLE SUMMARY: Pancreatic cancer is a devasting disease that has unfortunately proven very difficult to treat. …”
Publicado 2023
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36“…This condition can heighten the risk of pancreatic cancer (PC), a challenging disease with a high mortality rate. …”
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37“…Moreover, the review highlights promising pharmaceutical candidates for pancreatic cancer therapy. Overall, this comprehensive review provides valuable insights into the prospects of combating pancreatic cancer by selectively addressing cholesterol-related processes. …”
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38“…Pancreatic cancer remains a challenging disease with an overall cumulative 5-year survival rate below 1%. …”
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39“…This review will focus on the role of apoptotic proteins contributing to pancreatic cancer development and progression and will demonstrate possible targets to influence this deadly disease.…”
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