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  1. 4081
    “…Here, we evaluated the dependence of pancreatic cancer stem cells (PCSCs) on this non-canonical glutamine metabolism pathway and researched whether inhibiting this pathway can enhance radiosensitivity of PCSCs. …”
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    Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy
  2. 4082
    “…The Wnt/β-catenin signaling pathway, commonly hyperactivated in pancreatic cancer, has been reported to play an important role in the maintenance of stemness of cancer stem cells (CSCs), which is closely related to the progression of pancreatic cancer. …”
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    MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway
  3. 4083
    por Guo, Junli, Xie, Keping, Zheng, Shaojiang
    Publicado 2016
    “…Lack of early detection and effective interventions is a major reason for the poor prognosis and dismal survival rates for pancreatic cancer. Pancreatic intraepithelial neoplasia (PanIN) is the most common precursor of invasive pancreatic ductal adenocarcinoma (PDAC). …”
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    Molecular Biomarkers of Pancreatic Intraepithelial Neoplasia and Their Implications in Early Diagnosis and Therapeutic Intervention of Pancreatic Cancer
  4. 4084
    “…Locally advanced pancreatic cancer (LAPC) accounts for the 40% of the new diagnoses. …”
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    Local Ablative Strategies for Ductal Pancreatic Cancer (Radiofrequency Ablation, Irreversible Electroporation): A Review
  5. 4085
    “…BACKGROUND: Pancreatic cancer ranks as the fourth leading cause of cancer-related mortality in the USA. …”
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    Gemcitabine plus cisplatin versus gemcitabine alone in the treatment of pancreatic cancer: a meta-analysis
  6. 4086
    “…In addition we constructed stable mesothelin overexpressing lines of the pancreatic cancer line Panc02 by two methods and tested them for growth and tumorigencity in vitro and in vivo. …”
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    Murine mesothelin: characterization, expression, and inhibition of tumor growth in a murine model of pancreatic cancer
  7. 4087
    “…AIM: The present study was performed to investigate the effect of Phyllanthus amarus extracts on serum biochemical changes in azaserine induced pancreatic cancer in Wistar rats. MATERIALS AND METHODS: Pancreatic cancer was developed in Wistar rats by intraperitoneal administration of azaserine (cancer inducer) for 21 days at the concentration of 5 mg/kg body weight. …”
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    Effect of Phyllanthus amarus on serum biochemical changes in azaserine induced pancreatic cancer in Wistar rats
  8. 4088
    “…Mounting evidence from epidemiology studies suggests that whole grain intake may reduce pancreatic cancer risk, but convincing evidence is scarce. …”
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    Whole Grain Intake Reduces Pancreatic Cancer Risk: A Meta-Analysis of Observational Studies
  9. 4089
    “…The aim of this study was to examine the prognostic value of such measures for patients with metastatic pancreatic cancer undergoing gemcitabine therapy. METHODS: The control data from two Phase III studies were retrospectively used to develop (271 patients) and validate (398 patients) survival models. …”
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    Predicting survival of pancreatic cancer patients treated with gemcitabine using longitudinal tumour size data
  10. 4090
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    Metachronous pancreatic cancer originating from disseminated founder pancreatic intraductal neoplasias (PanINs)
  11. 4091
    “…METHODS: Subjects comprised 43 patients with histologically confirmed unresectable pancreatic cancer treated with first-line chemotherapy. …”
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    Increased tumour ADC value during chemotherapy predicts improved survival in unresectable pancreatic cancer
  12. 4092
    “…The association between long‐term variation of postdiagnosis platelets and survival of pancreatic cancer (PC) has never been discussed by using dynamic survival analysis method. …”
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    Kinetics of postdiagnosis platelet count with overall survival of pancreatic cancer: a counting process approach
  13. 4093
    “…Three types of high-volume centers were defined: high-volume (1) incidence center, based on the number of patients diagnosed with metastatic pancreatic cancer, (2) treatment center based on number of patients with metastatic pancreatic cancer who started treatment with palliative chemotherapy and (3) surgical center based on the number of resections with curative intent for pancreatic cancer. …”
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    Volume matters in the systemic treatment of metastatic pancreatic cancer: a population-based study in the Netherlands
  14. 4094
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    Delivery of improved oncolytic adenoviruses by mesenchymal stromal cells for elimination of tumorigenic pancreatic cancer cells
  15. 4095
    “…The drug-resistance of pancreatic cancer cells results in poor therapeutic effect. …”
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    MicroRNA-320a promotes 5-FU resistance in human pancreatic cancer cells
  16. 4096
    “…BACKGROUND: MUC4 is a high molecular weight membrane protein that is overexpressed in pancreatic cancer (PC) and is associated with the development and progression of this disease. …”
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    The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer
  17. 4097
    “…PURPOSE: To determine the safety, tolerability and maximum tolerated dose (MTD) of addition of erlotinib to bevacizumab and capecitabine-based definitive chemoradiation (CRT) in unresectable pancreatic cancer. METHODS: Seventeen patients with CT-staged, biopsy-proven unresectable pancreatic cancer were enrolled between 3/2008 and 10/2010. …”
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    Phase I Trial of Consolidative Radiotherapy with Concurrent Bevacizumab, Erlotinib and Capecitabine for Unresectable Pancreatic Cancer
  18. 4098
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    Specific MAPK-Associated MicroRNAs in Serum Differentiate Pancreatic Cancer from Autoimmune Pancreatitis
  19. 4099
    “…In this study, we investigated which N staging system was the most accurate at predicting survival in pancreatic cancer patients. Lymph node (LN) metastasis is known to be one of the important prognostic factors in resected pancreatic cancer. …”
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    Identification of an N staging system that predicts oncologic outcome in resected left-sided pancreatic cancer
  20. 4100
    “…Herein, we report a new class of nanoconstructs based on milk protein (casein)-coated magnetic iron oxide (CNIO) nanoparticles for targeted and image-guided pancreatic cancer treatment. The tumor-targeting amino-terminal fragment (ATF) of urokinase plasminogen activator and the antitumor drug cisplatin (CDDP) were engineered on this nanoplatform. …”
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    Functionalized milk-protein-coated magnetic nanoparticles for MRI-monitored targeted therapy of pancreatic cancer
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