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  1. 4101
    por Molina‐Montes, Esther, Sánchez, María‐José, Zamora‐Ros, Raul, Bueno‐de‐Mesquita, H.B(as), Wark, Petra A., Obon‐Santacana, Mireia, Kühn, Tilman, Katzke, Verena, Travis, Ruth C., Ye, Weimin, Sund, Malin, Naccarati, Alessio, Mattiello, Amalia, Krogh, Vittorio, Martorana, Caterina, Masala, Giovanna, Amiano, Pilar, Huerta, José‐María, Barricarte, Aurelio, Quirós, José‐Ramón, Weiderpass, Elisabete, Angell Åsli, Lene, Skeie, Guri, Ericson, Ulrika, Sonestedt, Emily, Peeters, Petra H., Romieu, Isabelle, Scalbert, Augustin, Overvad, Kim, Clemens, Matthias, Boeing, Heiner, Trichopoulou, Antonia, Peppa, Eleni, Vidalis, Pavlos, Khaw, Kay‐Tee, Wareham, Nick, Olsen, Anja, Tjønneland, Anne, Boutroun‐Rualt, Marie‐Christine, Clavel‐Chapelon, Françoise, Cross, Amanda J., Lu, Yunxia, Riboli, Elio, Duell, Eric J.
    Publicado 2016
    “…Despite the potential cancer preventive effects of flavonoids and lignans, their ability to reduce pancreatic cancer risk has not been demonstrated in epidemiological studies. …”
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    Flavonoid and lignan intake and pancreatic cancer risk in the European prospective investigation into cancer and nutrition cohort
  2. 4102
    “…We also found that TTP impairs pancreatic cancer cell proliferation both in vivo and in vitro. …”
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    Low tristetraprolin expression promotes cell proliferation and predicts poor patients outcome in pancreatic cancer
  3. 4103
    “…BACKGROUND: The management of locally advanced pancreatic cancer (LAPC) patients remains controversial. …”
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    Prognostic nomogram and score to predict overall survival in locally advanced untreated pancreatic cancer (PROLAP)
  4. 4104
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    Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment
  5. 4105
    “…To evaluate the potential contribution of miRNAs in acquired resistance to cisplatin in pancreatic cancer, we compared levels of more than 2000 human miRNAs in a cisplatin-resistant cell line (BxPC3-R) derived from parental (BxPC3) cells by step-wise exposure to increasing concentrations of the drug over more than 20 passages. …”
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    Evidence for the role of microRNA 374b in acquired cisplatin resistance in pancreatic cancer cells
  6. 4106
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    The tumor-inhibitory effectiveness of a novel anti-Trop2 Fab conjugate in pancreatic cancer
  7. 4107
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    The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer
  8. 4108
    “…Quantification of the association between the intake of selenium and risk of pancreatic cancer is still conflicting. Thus, we conducted a meta-analysis to summarize the evidence from epidemiological studies of selenium intake with the risk of pancreatic cancer. …”
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    Association between selenium intake and the risk of pancreatic cancer: a meta-analysis of observational studies
  9. 4109
    “…RESULTS: Esculetin treatment in all three pancreatic cancer cell lines resulted in significant growth inhibition with G1-phase cell cycle arrest and induction of mitochondrial dependent apoptosis through activation of caspases 3, 8 and 9. …”
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    Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1
  10. 4110
    “…However, the role of the CRP/Alb ratio in advanced pancreatic cancer (PC) has not been examined. A retrospective study of 233 patients with advanced PC was conducted. …”
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    The C-reactive protein/albumin ratio predicts overall survival of patients with advanced pancreatic cancer
  11. 4111
    “…More importantly, our work reveals that resveratrol is a potential anticancer agent for the treatment of pancreatic cancer, and YAP may serve as a promising target for sensitizing pancreatic cancer cells to chemotherapy.…”
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    YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine
  12. 4112
    “…Furthermore, pancreatic cancer cells migrate towards dorsal root ganglia (DRG) in a co-culture assay, indicating a paracrine NGF signaling between the DRGs and pancreatic cancer cells. …”
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    Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells
  13. 4113
    “…Biomarkers for the early diagnosis of pancreatic cancer (PC) are urgent needed. Plasma microRNAs (miRNAs) might be used as biomarkers for the diagnosis of cancer. …”
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    Plasma microRNA panels to diagnose pancreatic cancer: Results from a multicenter study
  14. 4114
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    Proteinase-Activated Receptor 2 Is a Novel Regulator of TGF-β Signaling in Pancreatic Cancer
  15. 4115
    por Muircroft, Wendy
    Publicado 2016
    “…Guidelines have been developed in Australasia to define the operability for patients who have been diagnosed with pancreatic cancer. This is supported by advances in pancreatic cancer genetics, which show potential for developing targeted therapies for pancreatic cancer. …”
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    An Australasian perspective on the curative treatment of patients with pancreatic cancer, supportive care, and future directions for management
  16. 4116
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    Erratum to: Integrative analysis of multi-omics data for identifying multi-markers for diagnosing pancreatic cancer
  17. 4117
    “…We propose that NMT1 is a novel regulator of cilia formation and tris DBA palladium a novel inhibitor of cilia formation and metastasis in pancreatic cancer. Thus, further evaluation of tris DBA palladium for the treatment of pancreatic cancer is warranted.…”
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    Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model
  18. 4118
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    Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer
  19. 4119
    “…Recently, the interest in studying pancreatic cancer mortality has increased due to its high lethality. …”
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    Spatial gender-age-period-cohort analysis of pancreatic cancer mortality in Spain (1990–2013)
  20. 4120
    “…BACKGROUND: The aim of this study was to determine whether checkpoint kinase 1 inihibitor (CHK1), LY2603618, and gemcitabine prolong overall survival (OS) compared to gemcitabine alone in patients with unresectable pancreatic cancer. METHODS: Patients with Stage II-IV locally advanced or metastatic pancreatic cancer were randomized (2:1) to either 230 mg of LY2603618/1000 mg/m(2) gemcitabine combined or 1000 mg/m(2) gemcitabine alone. …”
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    A phase II study to evaluate LY2603618 in combination with gemcitabine in pancreatic cancer patients
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