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4121
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4122por Ioka, T, Komatsu, Y, Mizuno, N, Tsuji, A, Ohkawa, S, Tanaka, M, Iguchi, H, Ishiguro, A, Kitano, M, Satoh, T, Yamaguchi, T, Takeda, K, Kida, M, Eguchi, K, Ito, T, Munakata, M, Itoi, T, Furuse, J, Hamada, C, Sakata, Y“…CONCLUSIONS: There was a trend for better PFS and OS in the IRIS group that could be a treatment arm in the clinical trials for gemcitabine-refractory pancreatic cancer.…”
Publicado 2017
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4123por Vallejo, Adrian, Perurena, Naiara, Guruceaga, Elisabet, Mazur, Pawel K., Martinez-Canarias, Susana, Zandueta, Carolina, Valencia, Karmele, Arricibita, Andrea, Gwinn, Dana, Sayles, Leanne C., Chuang, Chen-Hua, Guembe, Laura, Bailey, Peter, Chang, David K., Biankin, Andrew, Ponz-Sarvise, Mariano, Andersen, Jesper B., Khatri, Purvesh, Bozec, Aline, Sweet-Cordero, E. Alejandro, Sage, Julien, Lecanda, Fernando, Vicent, Silve“…High FOSL1 expression identifies mutant KRAS lung and pancreatic cancer patients with the worst survival outcome. …”
Publicado 2017
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4124por Zhou, Pingting, Li, Bo, Liu, Furao, Zhang, Meichao, Wang, Qian, Liu, Yuanhua, Yao, Yuan, Li, Dong“…In particular, pancreatic cancer stem cells (PCSCs) are functionally important during tumor relapse and therapy resistance. …”
Publicado 2017
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4125por Peng, Yun-Peng, Xi, Chun-Hua, Zhu, Yi, Yin, Ling-Di, Wei, Ji-Shu, Zhang, Jing-Jing, Liu, Xin-Chun, Guo, Song, Fu, Yue, Miao, Yi“…The progression of pancreatic cancer (PC) is significantly associated with tumor immune escape, which may be associated with nature killer (NK) cell dysfunction. …”
Publicado 2016
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4126
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4127por Kwon, Jason J., Willy, Jeffrey A., Quirin, Kayla A., Wek, Ronald C., Korc, Murray, Yin, Xiao-Ming, Kota, Janaiah“…In an effort to develop novel therapeutic strategies, we found downregulation of miR-29 in pancreatic cancer cells, and overexpression of miR-29a sensitized chemotherapeutic resistant pancreatic cancer cells to gemcitabine, reduced cancer cell viability, and increased cytotoxicity. …”
Publicado 2016
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4128Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein“…Due to early onset of local invasion and distant metastasis, pancreatic cancer is the most lethal human malignant tumor, with a 5 year survival rate of less than 5%. …”
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4129por Knudsen, Erik S., Balaji, Uthra, Freinkman, Elizaveta, McCue, Peter, Witkiewicz, Agnieszka K.Enlace del recurso
Publicado 2016
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4130por Le Calvez-Kelm, Florence, Foll, Matthieu, Wozniak, Magdalena B., Delhomme, Tiffany M., Durand, Geoffroy, Chopard, Priscilia, Pertesi, Maroulio, Fabianova, Eleonora, Adamcakova, Zora, Holcatova, Ivana, Foretova, Lenka, Janout, Vladimir, Vallee, Maxime P., Rinaldi, Sabina, Brennan, Paul, McKay, James D., Byrnes, Graham B., Scelo, Ghislaine“…The utility of KRAS mutations in plasma circulating cell-free DNA (cfDNA) samples as non-invasive biomarkers for the detection of pancreatic cancer has never been evaluated in a large case-control series. …”
Publicado 2016
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4131por Zhou, Xiuxia, Su, Jingna, Feng, Shaoyan, Wang, Lixia, Yin, Xuyuan, Yan, Jingzhe, Wang, Zhiwei“…Pancreatic cancer (PC) is one of the most aggressive human malignancies worldwide and is the fourth leading cause of cancer-related deaths. …”
Publicado 2016
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4132por Behboudi Farahbakhsh, Faegheh, Nazemalhosseini Mojarad, Ehsan, Azimzadeh, Pedram, Goudarzi, Faezeh, Mohammad Alizadeh, Amir Houshang, Haghazali, Mehrdad, Mahmoudi Lamoki, Reza, Asadzadeh Aghdaei, Hamid“…BACKGROUND: Ninety percent of pancreatic cancer patients have less than 5-year overall survival and approximately 50% of cases were diagnosed with metastasis in the time of admission. …”
Publicado 2017
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4133por Sharbeen, George, Youkhana, Janet, Mawson, Amanda, McCarroll, Joshua, Nunez, Andrea, Biankin, Andrew, Johns, Amber, Goldstein, David, Phillips, PhoebeEnlace del recurso
Publicado 2016
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4134“…The role of microRNA in the aberrant autophagy that occurs in pancreatic cancer remains controversial. Because hypoxia is known to induce autophagy, we screened for differentially expressed microRNAs using a miRNA microarray with pancreatic cancer cells cultured under normoxic and hypoxic conditions. …”
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4135por Golan, Talia, Sella, Tal, O'Reilly, Eileen M, Katz, Matthew H G, Epelbaum, Ron, Kelsen, David P, Borgida, Ayelet, Maynard, Hannah, Kindler, Hedy, Friedmen, Eitan, Javle, Milind, Gallinger, Steven“…Controls included surgically resected PDAC cases treated during the same time period that were either BRCA non-carriers, or had no family history of breast, ovarian or pancreatic cancers. Cases and controls were matched by: age at diagnosis (within ±5-year period) and institution. …”
Publicado 2017
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4136por Shan, Tao, Chen, Shuo, Chen, Xi, Lin, Wan Run, Li, Wei, Ma, Jiancang, Wu, Tao, Cui, Xijuan, Ji, Hong, Li, Yiming, Kang, Ya'An“…We investigated the mechanism of cancer-associated fibroblasts (CAFs) in promoting the invasion and metastasis of pancreatic cancer cells in a non-vascular manner. We verified the original generation of isolated cultured CAFs and normal fibroblasts (NFs) based on the expression of α-SMA and vimentin, and we examined the cell glycolysis level through glucose consumption and lactate production experiments. …”
Publicado 2017
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4137por Nuzhat, Zarin, Kinhal, Vyjayanthi, Sharma, Shayna, Rice, Gregory E., Joshi, Virendra, Salomon, Carlos“…Pancreatic cancer is the fourth most common cause of death due to cancer in the world. …”
Publicado 2016
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4138“…Pancreatic cancer (PaCa) is a highly metastatic cancer, and patients are at high risk of developing venous thromboembolism (VTE). …”
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4139por Mehrotra, Shikhar, Britten, Carolyn D., Chin, Steve, Garrett-Mayer, Elizabeth, Cloud, Colleen A., Li, Mingli, Scurti, Gina, Salem, Mohamed L., Nelson, Michelle H., Thomas, Melanie B., Paulos, Chrystal M., Salazar, Andres M., Nishimura, Michael I., Rubinstein, Mark P., Li, Zihai, Cole, David J.“…Thus, we posit that DC-based immunotherapy, in conjunction with toll-like receptor (TLR)-3 agonist poly-ICLC, is a promising approach for harnessing immunity against metastatic or locally advanced unresectable pancreatic cancer (PC). METHODS: We generated autologous DCs from the peripheral blood of HLA-A2(+) patients with PC. …”
Publicado 2017
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4140por Nguyen, Andrew H., Elliott, Irmina A., Wu, Nanping, Matsumura, Cynthia, Vogelauer, Maria, Attar, Narsis, Dann, Amanda, Ghukasyan, Razmik, Toste, Paul A., Patel, Sanjeet G., Williams, Jennifer L., Li, Luyi, Dawson, David W., Radu, Caius, Kurdistani, Siavash K., Donahue, Timothy R.Enlace del recurso
Publicado 2016
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