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  1. 4161
    “…Pancreatic cancer (PC), characterized by aggressive local invasion and metastasis, is one of the most malignant cancers. …”
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    Gemcitabine-induced heparanase promotes aggressiveness of pancreatic cancer cells via activating EGFR signaling
  2. 4162
    “…BACKGROUND: Carcinoembryonic antigen (CEA) is one of the most widely used tumor markers and is increased in 30%–60% of patients with pancreatic cancer. Although carbohydrate antigen 19-9 (CA19-9) is the most important serum biomarker in pancreatic cancer, the diagnostic and prognostic value of CEA is gradually being recognized. …”
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    Diagnostic and prognostic value of carcinoembryonic antigen in pancreatic cancer: a systematic review and meta-analysis
  3. 4163
    “…In the present study, the expression of BNIP3 in pancreatic cancer tissues, the correlation with clinicopathological characteristics and prognosis and the regulation of this protein in pancreatic cancer cell lines with regard to the induction of apoptosis were investigated. …”
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    Methylation of BNIP3 in pancreatic cancer inhibits the induction of mitochondrial-mediated tumor cell apoptosis
  4. 4164
    “…This study examined the role of exosomes in pancreatic cancer cell adhesion, migration, and invasion. …”
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    Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation
  5. 4165
    “…Many cancer types, including pancreatic cancer, have a dense fibrotic stroma that plays an important role in tumor progression and invasion. …”
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    Preparation and Metabolic Assay of 3-dimensional Spheroid Co-cultures of Pancreatic Cancer Cells and Fibroblasts
  6. 4166
    “…Pancreatic cancer has a high rate of local recurrence and poor prognosis even with adjuvant chemotherapy after curative resection. …”
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    Synergistic effect of a drug loaded electrospun patch and systemic chemotherapy in pancreatic cancer xenograft
  7. 4167
    “…OBJECTIVES: Pancreatic cancer is one of the most common malignancies of the digestive system, and remains a clinical challenge. …”
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    Biological nanoparticles carrying the Hmda-7 gene are effective in inhibiting pancreatic cancer in vitro and in vivo
  8. 4168
    “…We undertook a barcode labelled short-hairpin (shRNA) library screen in pancreatic cancer cells in order to identify novel genes promoting cancer survival and progression. …”
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    The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators
  9. 4169
    “…Pancreatic cancer remains one of the most deadly cancers with a grave prognosis. …”
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    Autocrine DUSP28 signaling mediates pancreatic cancer malignancy via regulation of PDGF-A
  10. 4170
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    Exclusive and Combined Use of Statins and Aspirin and the Risk of Pancreatic Cancer: a Case-Control Study
  11. 4171
    “…Tenascin-C (TNC), a large extracellular matrix glycoprotein, has been reported to be associated with metastasis and poor prognosis in pancreatic cancer. However, the effects and mechanisms of TNC in pancreatic cancer metastasis largely remain unclear. …”
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    Tenascin-C induces migration and invasion through JNK/c-Jun signalling in pancreatic cancer
  12. 4172
    “…Our recent studies have uncovered that in pancreatic cancer, the KRAS mutation decreased FBW7 expression through phosphorylation and subsequent ubiquitination. …”
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    FBW7 increases the chemosensitivity of pancreatic cancer cells to gemcitabine through upregulation of ENT1
  13. 4173
    “…BACKGROUND: (18)F-FDG PET/CT could satisfactorily show pancreatic and extra-pancreatic lesions in AIP, which can be mistaken for pancreatic cancer (PC). This study aimed to identify (18)F-FDG PET/CT findings that might differentiate AIP from PC. …”
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    (18)F- FDG PET/CT helps differentiate autoimmune pancreatitis from pancreatic cancer
  14. 4174
    “…PURPOSE: Neoadjuvant treatment may provide improved survival outcomes for patients with borderline resectable pancreatic cancer (BRPC). The purpose of this study is to evaluate the clinical outcomes of neoadjuvant treatment and to identify prognostic factors. …”
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    Survival outcome and prognostic factors of neoadjuvant treatment followed by resection for borderline resectable pancreatic cancer
  15. 4175
    “…Here, we report a case of oxaliplatin-induced hyperammonemic encephalopathy occurring after gemcitabine plus oxaliplatin (GEMOX) chemotherapy in a patient with pancreatic cancer. A 76-year-old man received GEMOX regimen as first-line treatment for pancreatic adenocarcinoma with peritoneal dissemination. …”
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    Oxaliplatin-Induced Hyperammonemic Encephalopathy in a Patient with Metastatic Pancreatic Cancer: A Case Report
  16. 4176
    “…We have previously reported that GRN163L could shorten telomeres and limit the lifespan of CD18/HPAF and CAPAN1 pancreatic cancer cells. Here, we examined the effects of GRN163L on two other pancreatic cancer cell lines: AsPC1 and L3.6pl. …”
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    Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells
  17. 4177
    “…In conclusion, our results demonstrate a novel role of platelets in modulating chemoresistance in pancreatic cancer. Moreover, we propose ADP/ATP receptors as additional potential drug targets for treatment of pancreatic cancer.…”
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    The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance
  18. 4178
    “…The main focus of pancreatic cancer research should continue to be at the molecular, genetic, and immunologic levels.…”
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    Can pancreatic cancer behavior be predicted based on computed tomography measurements of fat and muscle mass?
  19. 4179
    “…In a Kras(G12D)-driven pancreatic cancer mouse model, intraductal delivery of scAAV6.GFP targeted acini, epithelial, and stromal cells and exhibited persistent gene expression 5 months post-delivery. …”
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    Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice
  20. 4180
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    Dexamethasone mediates pancreatic cancer progression by glucocorticoid receptor, TGFβ and JNK/AP-1
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