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641
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642por McCarroll, Joshua, Teo, Joann, Boyer, Cyrille, Goldstein, David, Kavallaris, Maria, Phillips, Phoebe A.“…It is established that pancreatic cancer is a highly heterogeneous disease with a complex tumor microenvironment. …”
Publicado 2014
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643por Xiao, Zhiwen, Luo, Guopei, Liu, Chen, Wu, Chuntao, Liu, Liang, Liu, Zuqiang, Ni, Quanxing, Long, Jiang, Yu, Xianjun“…In this review, we will summarize the latest advances on lymphatic metastasis in pancreatic cancer.…”
Publicado 2014
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644“…Many chemotherapy and targeted agents were combined with gemcitabine but failed to demonstrate improvement in pancreatic cancer (PC) survival. Taxanes (paclitaxel, docetaxel) were introduced in the clinic as anti-microtubule agents and showed activity against PC cells in vitro; however, clinical efficacy was limited. …”
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645por Tan, Carlyn R., Yaffee, Patrick M., Jamil, Laith H., Lo, Simon K., Nissen, Nicholas, Pandol, Stephen J., Tuli, Richard, Hendifar, Andrew E.“…Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately, its treatment is complex and remains a challenge. …”
Publicado 2014
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646“…BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer with a 5-year survival rate of less than 1-2%. Early onset pancreatic cancer (EOPC), i.e. patients below 50 years of age, is infrequently described. …”
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647por McCarroll, Joshua A., Naim, Stephanie, Sharbeen, George, Russia, Nelson, Lee, Julia, Kavallaris, Maria, Goldstein, David, Phillips, Phoebe A.“…This review will discuss how PSCs contribute to chemoresistance in pancreatic cancer.…”
Publicado 2014
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648por Lutz, Eric, Kinkead, Heather, Yager, Allison, Armstrong, Todd, Lauer, Peter, Brockstedt, Dirk, Dubensky, Thomas, Jaffee, ElizabethEnlace del recurso
Publicado 2013
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649por Jiang, Yixing, DiVittore, Nicole A., Young, Megan M, Jia, Zhiliang, Xie, Keping, Ritty, Timothy M., Kester, Mark, Fox, Todd E.“…Although numerous genetic mutations and amplifications have been identified in pancreatic cancer, much of the molecular pathogenesis of the disease remains undefined. …”
Publicado 2013
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650“…Pancreatic cancer is a highly lethal tumor type for which there are few viable therapeutic options. …”
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651por Kwak, Yoo-Kang, Lee, Jong Hoon, Lee, Myung-Ah, Chun, Hoo-Geun, Kim, Dong-Goo, You, Young Kyoung, Hong, Tae-Ho, Jang, Hong Seok“…PURPOSE: Survival outcome of locally advanced pancreatic cancer has been poor and little is known about prognostic factors of the disease, especially in locally advanced cases treated with concurrent chemoradiation. …”
Publicado 2014
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652“…Pancreatic cancer remains largely an incurable disease necessitating the development of novel therapeutic approaches. …”
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653“…Thus, re-activation of antitumor immunity should be investigated for use in pancreatic cancer prevention and therapy.…”
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654por Nishikawa, Yoshihiro, Tsuji, Yoshihisa, Isoda, Hiroyoshi, Kodama, Yuzo, Chiba, Tsutomu“…The objective was to investigate the relationship between prognosis in case of pancreatic cancer and perfusion in tissue surrounding pancreatic cancer using perfusion CT. …”
Publicado 2014
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656
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657por Lili, Loukia N., Matyunina, Lilya V., Walker, L. DeEtte, Daneker, George W., McDonald, John F.“…METHODS: In an effort to explore this question in pancreatic cancer, we compared the most significantly differentially expressed genes/pathways between cancer and control patient samples as determined by group versus personalized analyses. …”
Publicado 2014
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658por Kim, Kiyoun, Ahn, Soohyun, Lim, Johan, Yoo, Byong Chul, Hwang, Jin-Hyeok, Jang, Woncheol“…BACKGROUND: Pancreatic cancer is the fourth leading cause of cancer-related deaths. …”
Publicado 2015
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660“…Pancreatic cancer (PC) has been estimated to have higher incidence and correspondingly higher mortality rates in more developed regions worldwide. …”
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