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661por Chari, Suresh T., Kelly, Kimberly, Hollingsworth, Michael A., Thayer, Sarah P., Ahlquist, David A., Andersen, Dana K., Batra, Surinder K., Brentnall, Teresa A., Canto, Marcia, Cleeter, Deborah F., Firpo, Matthew A., Gambhir, Sanjiv Sam, Go, Vay Liang W., Hines, O. Joe, Kenner, Barbara J., Klimstra, David S., Lerch, Markus M., Levy, Michael J., Maitra, Anirban, Mulvihill, Sean J., Petersen, Gloria M., Rhim, Andrew D., Simeone, Diane M., Srivastava, Sudhir, Tanaka, Masao, Vinik, Aaron I., Wong, David“…Pancreatic cancer (PC) is estimated to become the second leading cause of cancer death in the United States by 2020. …”
Publicado 2015
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662“…Pancreatic cancer remains one of the most intractable cancers, with a dismal prognosis reflected by a 5-year survival of ~ 6%. …”
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663“…Thus, the combined serial analysis of mutant DNA and miR in the circulation has the potential to provide a molecular footprint of pancreatic cancer and can be used to monitor treatment responses or resistance to treatment in real time with a minimally invasive procedure.…”
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664por HAN, DONG-YAN, FU, DA, XI, HAO, LI, QIAN-YU, FENG, LI-JIN, ZHANG, WEI, JI, GUO, XIAO, JIA-CHENG, WEI, QING“…Pancreatic cancer is a polygenic disease and the fourth leading cause of cancer-associated mortality worldwide; however, the tumorigenesis of pancreatic cancer remains poorly understood. …”
Publicado 2015
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665por Desai, Neelam V, Sliesoraitis, Sarunas, Hughes, Steven J, Trevino, Jose G, Zlotecki, Robert A, Ivey, Alison M, George, Thomas J“…However, despite advances in therapies for patients with advanced pancreatic cancer, only surgery has consistently proven to improve long-term survival. …”
Publicado 2015
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666“…Despite recent advances in the production of genetically engineered mouse models (GEMMs), the development of new therapies for pancreatic cancer is still hampered by a lack of reliable and predictive preclinical animal models for this disease. …”
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668“…Despite the variety of approaches that have been improved to achieve a good understanding of pancreatic cancer (PC), the prognosis of PC remains poor, and the survival rates are dismal. …”
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669“…Pancreatic cancer (PDAC) is the fourth leading cause of cancer-related mortality in the Western world and, even in 2014, a therapeutic challenge. …”
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671por Zhang, Lun, Li, Jiahui, Zong, Liang, Chen, Xin, Chen, Ke, Jiang, Zhengdong, Nan, Ligang, Li, Xuqi, Li, Wei, Shan, Tao, Ma, Qingyong, Ma, Zhenhua“…Pancreatic cancer is the fourth leading cause of cancer-related death in the United States. …”
Publicado 2016
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672“…Recently, the roles of microRNAs (miRNAs) in the development and progression of pancreatic cancer became a hot topic in the scientific community of pancreatic cancer research. …”
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674por Ramadani, Naser, Dedushi, Kreshnike, Muçaj, Sefedin, Kabashi, Serbeze, Jerliu, Naim, Hoxhaj, Astrit“…THE AIM: The aim of this paper is to analyze different factors that influence the trends of pancreatic cancer mortality and morbidity of patients treated at the UCCK of Kosovo. …”
Publicado 2016
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675por Edderkaoui, Mouad, Xu, Shiping, Chheda, Chintan, Morvaridi, Susan, Hu, Robert W., Grippo, Paul J., Mascariñas, Emman, Principe, Daniel R., Knudsen, Beatrice, Xue, Jing, Habtezion, Aida, Uyeminami, Dale, Pinkerton, Kent E., Pandol, Stephen J.Enlace del recurso
Publicado 2016
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676por Al Shemaili, Jasem, Parekh, Khatija A., Newman, Robert A., Hellman, Björn, Woodward, Carl, Adem, Abdu, Collin, Peter, Adrian, Thomas E.“…Frondoside A potently inhibited growth of pancreatic cancer cells with an EC(50) of ~1 µM. Frondoside B was less potent (EC(50) ~2.5 µM). …”
Publicado 2016
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677por Karanikas, Michail, Esempidis, Agis, Chasan, Zeinep Tzoutze Memet, Deftereou, Theodora, Antonopoulou, Maria, Bozali, Ferdi, Amarantidis, Kyriakos, Man, Yan-Gao“…Pancreatic cancer is considered one of the most lethal malignances. …”
Publicado 2016
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678por Crane, Christopher H.“…The role of radiation in locally advanced unresectable pancreatic cancer (LAPC) is controversial. Randomized trials evaluating standard doses of chemoradiation have not shown a significant benefit from the use of consolidative radiation. …”
Publicado 2016
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679“…BACKGROUND: Pancreatic cancer is one of the most lethal cancers worldwide, due to the lack of efficient therapy and difficulty in early diagnosis. …”
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680por Schlomann, Uwe, Koller, Garrit, Conrad, Catharina, Ferdous, Taheera, Golfi, Panagiota, Garcia, Adolfo Molejon, Höfling, Sabrina, Parsons, Maddy, Costa, Patricia, Soper, Robin, Bossard, Maud, Hagemann, Thorsten, Roshani, Rozita, Sewald, Norbert, Ketchem, Randal R., Moss, Marcia L., Rasmussen, Fred H., Miller, Miles A., Lauffenburger, Douglas A., Tuveson, David A., Nimsky, Christopher, Bartsch, Jörg W.“…Thus, our data integrate ADAM8 in pancreatic cancer signalling and validate ADAM8 as a target for PDAC therapy.…”
Publicado 2015
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